Drug conjugate-based anticancer therapy - Current status and perspectives
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Title
Drug conjugate-based anticancer therapy - Current status and perspectives
Authors
Keywords
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Journal
CANCER LETTERS
Volume 552, Issue -, Pages 215969
Publisher
Elsevier BV
Online
2022-10-22
DOI
10.1016/j.canlet.2022.215969
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Note: Only part of the references are listed.- Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases
- (2022) Debu Tripathy et al. JAMA Oncology
- Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy
- (2022) Dina V. Hingorani et al. Nature Communications
- Peptide–Drug Conjugates with Different Linkers for Cancer Therapy
- (2021) Mona Alas et al. JOURNAL OF MEDICINAL CHEMISTRY
- Brain penetrating peptides and peptide–drug conjugates to overcome the blood–brain barrier and target CNS diseases
- (2021) Xue Zhou et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Unlocking the potential of antibody–drug conjugates for cancer therapy
- (2021) Joshua Z. Drago et al. Nature Reviews Clinical Oncology
- Recent Advances and Trends in Chemical CPP–Drug Conjugation Techniques
- (2021) Félix Gayraud et al. MOLECULES
- Polypeptides–Drug Conjugates for Anticancer Therapy
- (2021) Yu Zhang et al. Advanced Healthcare Materials
- A Simple and Efficient Method to Generate Dual Site-Specific Conjugation ADCs with Cysteine Residue and an Unnatural Amino Acid
- (2021) Lin Zhang et al. BIOCONJUGATE CHEMISTRY
- First-in-Human, Phase 1 Dose-Escalation Study of Biparatopic Anti-HER2 Antibody–Drug Conjugate MEDI4276 in Patients with HER2-positive Advanced Breast or Gastric Cancer
- (2021) Mark D. Pegram et al. MOLECULAR CANCER THERAPEUTICS
- A Biparatopic Antibody–Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade
- (2021) John O. DaSilva et al. MOLECULAR CANCER THERAPEUTICS
- The promising role of antibody drug conjugate in cancer therapy: Combining targeting ability with cytotoxicity effectively
- (2021) Wen‐Qian Li et al. Cancer Medicine
- Advances and Limitations of Antibody Drug Conjugates for Cancer
- (2021) Candice Maria Mckertish et al. Biomedicines
- Reduction-Sensitive Dextran–Paclitaxel Polymer–Drug Conjugate: Synthesis, Self-Assembly into Nanoparticles, and In Vitro Anticancer Efficacy
- (2021) Sidra Kanwal et al. BIOCONJUGATE CHEMISTRY
- Development of bifunctional anti-PD-L1 antibody MMAE conjugate with cytotoxicity and immunostimulation
- (2021) Dian Xiao et al. BIOORGANIC CHEMISTRY
- Immune Modulating Antibody–Drug Conjugate (IM-ADC) for Cancer Immunotherapy
- (2021) Lei He et al. JOURNAL OF MEDICINAL CHEMISTRY
- Peptide–drug conjugate-based novel molecular drug delivery system in cancer
- (2021) Yi-Shen Zhu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Recent advances and challenges of bispecific antibodies in solid tumors
- (2021) Yuze Wu et al. Experimental Hematology & Oncology
- ANG1005, a brain penetrating peptide-drug conjugate, shows activity in patients with breast cancer with leptomeningeal carcinomatosis and recurrent brain metastases
- (2020) Priya Kumthekar et al. CLINICAL CANCER RESEARCH
- Role of Sheet-Edge Interactions in β-sheet Self-Assembling Peptide Hydrogels
- (2020) Jacek K. Wychowaniec et al. BIOMACROMOLECULES
- Trastuzumab Deruxtecan: First Approval
- (2020) Susan J. Keam DRUGS
- Use of a non-invasive brain penetrating peptide-drug conjugate strategy to improve the delivery of opioid pain relief medications to the brain
- (2020) Emilie Eiselt et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Tumor-Cell-Surface Adherable Peptide-Drug Conjugate Prodrug Nanoparticles Inhibit Tumor Metastasis and Augment Treatment Efficacy
- (2020) Chen Qian et al. NANO LETTERS
- Recent advances of antibody drug conjugates for clinical applications
- (2020) Pengxuan Zhao et al. Acta Pharmaceutica Sinica B
- Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors
- (2020) Dina V. Hingorani et al. BIOMATERIALS
- Peptide-Drug Conjugates and Their Targets in Advanced Cancer Therapies
- (2020) Paul Hoppenz et al. Frontiers in Chemistry
- Phage Display-Based Homing Peptide-Daunomycin Conjugates for Selective Drug Targeting to PANC-1 Pancreatic Cancer
- (2020) Levente E. Dókus et al. Pharmaceutics
- Belantamab Mafodotin: First Approval
- (2020) Anthony Markham DRUGS
- Discovery of novel cell-penetrating and tumor-targeting peptide-drug conjugate (PDC) for programmable delivery of paclitaxel and cancer treatment
- (2020) Xin Deng et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent Advances in Cell Penetrating Peptide-Based Anticancer Therapies
- (2019) Justine Habault et al. MOLECULES
- The Role of Organic Synthesis in the Emergence and Development of Antibody-Drug Conjugates as Targeted Cancer Therapies
- (2019) Kyriacos C. Nicolaou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Peptide–Drug Conjugate-Based Nanocombination Actualizes Breast Cancer Treatment by Maytansinoid and Photothermia with the Assistance of Fluorescent and Photoacoustic Images
- (2019) Yanan Sun et al. NANO LETTERS
- The Analysis of Key Factors Related to ADCs Structural Design
- (2019) Haichao Tang et al. Frontiers in Pharmacology
- Innovative Linker Strategies for Tumor‐Targeted Drug Conjugates
- (2019) Alberto Dal Corso et al. CHEMISTRY-A EUROPEAN JOURNAL
- Targeting Triple Negative Breast Cancer Cells with Novel Cytotoxic Peptide–Doxorubicin Conjugates
- (2019) Elmira Ziaei et al. BIOCONJUGATE CHEMISTRY
- 177Lu-DOTATATE for the treatment of gastroenteropancreatic neuroendocrine tumors
- (2019) Satya Das et al. Expert Review of Gastroenterology & Hepatology
- A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects
- (2019) Jackson K. Burton et al. AAPS Journal
- Tumor-Targeting Peptides: Ligands for Molecular Imaging and Therapy
- (2018) Ning Zhao et al. Anti-Cancer Agents in Medicinal Chemistry
- Peptide chemistry toolbox – Transforming natural peptides into peptide therapeutics
- (2018) Miloš Erak et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody
- (2018) Vaheh Oganesyan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures
- (2018) Xueguang Lu et al. Nano Research
- Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia
- (2018) Jeffrey Baron et al. Expert Review of Clinical Pharmacology
- Type of pH sensitive linker reveals different time-dependent intracellular localization, in vitro and in vivo efficiency in alpha-fetoprotein receptor targeted doxorubicin conjugate
- (2018) M. Mollaev et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Polymeric Nanocarriers for the Delivery of Antimalarials
- (2018) Zandile Mhlwatika et al. MOLECULES
- Polymer–drug conjugate therapeutics: advances, insights and prospects
- (2018) Iriny Ekladious et al. NATURE REVIEWS DRUG DISCOVERY
- Development and evaluation of β-galactosidase-sensitive antibody-drug conjugates
- (2017) Sergii Kolodych et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent advances of bispecific antibodies in solid tumors
- (2017) Shengnan Yu et al. Journal of Hematology & Oncology
- Routes for Drug Translocation Across the Blood-Brain Barrier: Exploiting Peptides as Delivery Vectors
- (2017) Mie Kristensen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Bispecific Antibodies and Antibody–Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs
- (2017) Julian Andreev et al. MOLECULAR CANCER THERAPEUTICS
- Strategies and challenges for the next generation of antibody–drug conjugates
- (2017) Alain Beck et al. NATURE REVIEWS DRUG DISCOVERY
- Cell-Penetrating Peptides: From Basic Research to Clinics
- (2017) Giulia Guidotti et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Novel Phosphate Modified Cathepsin B Linkers: Improving Aqueous Solubility and Enhancing Payload Scope of ADCs
- (2016) Jeffrey C. Kern et al. BIOCONJUGATE CHEMISTRY
- Antibody-drug conjugates—an emerging class of cancer treatment
- (2016) Nikolaos Diamantis et al. BRITISH JOURNAL OF CANCER
- A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
- (2016) John Y. Li et al. CANCER CELL
- Blood–brain barrier shuttle peptides: an emerging paradigm for brain delivery
- (2016) Benjamí Oller-Salvia et al. CHEMICAL SOCIETY REVIEWS
- Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications
- (2016) Anisha A. D’souza et al. Expert Opinion on Drug Delivery
- The function of activatable cell-penetrating peptides in human intrahepatic bile duct epithelial cells
- (2016) Kui Tu et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Efficient Payload Delivery by a Bispecific Antibody-Drug Conjugate Targeting HER2 and CD63
- (2016) B. E. C. G. de Goeij et al. MOLECULAR CANCER THERAPEUTICS
- Advances in Antibody Design
- (2015) Kathryn E. Tiller et al. Annual Review of Biomedical Engineering
- Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial
- (2015) Craig H Moskowitz et al. LANCET
- Etirinotecan pegol (NKTR-102) versus treatment of physician's choice in women with advanced breast cancer previously treated with an anthracycline, a taxane, and capecitabine (BEACON): a randomised, open-label, multicentre, phase 3 trial
- (2015) Edith A Perez et al. LANCET ONCOLOGY
- Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index
- (2015) Robert P Lyon et al. NATURE BIOTECHNOLOGY
- Immunogenicity of Antibody Drug Conjugates: Bioanalytical Methods and Monitoring Strategy for a Novel Therapeutic Modality
- (2014) M. Benjamin Hock et al. AAPS Journal
- β-Glucuronidase-responsive prodrugs for selective cancer chemotherapy: An update
- (2014) Isabelle Tranoy-Opalinski et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Dual Targeting of Integrin v 3 and Matrix Metalloproteinase-2 for Optical Imaging of Tumors and Chemotherapeutic Delivery
- (2014) J. L. Crisp et al. MOLECULAR CANCER THERAPEUTICS
- IgG Subclasses and Allotypes: From Structure to Effector Functions
- (2014) Gestur Vidarsson et al. Frontiers in Immunology
- Recent advances in amino acid N-carboxyanhydrides and synthetic polypeptides: chemistry, self-assembly and biological applications
- (2013) Hua Lu et al. CHEMICAL COMMUNICATIONS
- Cathepsin B as a cancer target
- (2013) Christopher S Gondi et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Peptides and peptide conjugates: therapeutics on the upward path
- (2012) Verena M Ahrens et al. Future Medicinal Chemistry
- Targeted drug delivery for cancer therapy: the other side of antibodies
- (2012) Michael A Firer et al. Journal of Hematology & Oncology
- Two Hundred Years of Cancer Research
- (2012) Vincent T. DeVita et al. NEW ENGLAND JOURNAL OF MEDICINE
- Peptides for cell-selective drug delivery
- (2012) Nina Svensen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy
- (2011) Gonçalo J. L. Bernardes et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
- (2010) Katrin Knop et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tumor Delivery and In Vivo Processing of Disulfide-Linked and Thioether-Linked Antibody−Maytansinoid Conjugates
- (2009) Hans K. Erickson et al. BIOCONJUGATE CHEMISTRY
- Glutathione: Overview of its protective roles, measurement, and biosynthesis
- (2008) Henry Jay Forman et al. MOLECULAR ASPECTS OF MEDICINE
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
- (2008) Jagath R Junutula et al. NATURE BIOTECHNOLOGY
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