Imaging and serum biomarkers reflecting the functional efficacy of extended erythropoietin treatment in rats following infantile traumatic brain injury

Evaluation of gait impairment in mice subjected to craniotomy and traumatic brain injury

(2015) M. Sashindranath et al.   BEHAVIOURAL BRAIN RESEARCH

Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats

(2015) Xiaohuan Gu et al.   EXPERIMENTAL NEUROLOGY

Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo

(2015) S. Sivakumaran et al.   JOURNAL OF NEUROSCIENCE

Closed Head Injury in an Age-Related Alzheimer Mouse Model Leads to an Altered Neuroinflammatory Response and Persistent Cognitive Impairment

(2015) S. J. Webster et al.   JOURNAL OF NEUROSCIENCE

Incidence of seizures on continuous EEG monitoring following traumatic brain injury in children

(2015) Brent R. O’Neill et al.   Journal of Neurosurgery-Pediatrics

Acute Temporal Profiles of Serum Levels of UCH-L1 and GFAP and Relationships to Neuronal and Astroglial Pathology following Traumatic Brain Injury in Rats

(2015) Xian-jian Huang et al.   JOURNAL OF NEUROTRAUMA

Systematic Review of Clinical Studies Examining Biomarkers of Brain Injury in Athletes after Sports-Related Concussion

(2015) Linda Papa et al.   JOURNAL OF NEUROTRAUMA

Measurement of the Glial Fibrillary Acidic Protein and Its Breakdown Products GFAP-BDP Biomarker for the Detection of Traumatic Brain Injury Compared to Computed Tomography and Magnetic Resonance Imaging

(2015) Paul J. McMahon et al.   JOURNAL OF NEUROTRAUMA

A New Rabbit Model of Pediatric Traumatic Brain Injury

(2015) Zhi Zhang et al.   JOURNAL OF NEUROTRAUMA

Safety of Early High-Dose Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants

(2015) Jean-Claude Fauchère et al.   JOURNAL OF PEDIATRICS

Prenatal Hypoxia–Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone

(2015) Lauren L. Jantzie et al.   Frontiers in Cellular Neuroscience

Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain

(2015) A Winkelmann et al.   Cell Death & Disease

Tract shape modeling detects changes associated with preterm birth and neuroprotective treatment effects

(2015) Devasuda Anblagan et al.   NeuroImage-Clinical

White matter disruption in moderate/severe pediatric traumatic brain injury: Advanced tract-based analyses

(2015) Emily L. Dennis et al.   NeuroImage-Clinical

Blood Biomarkers in Moderate-To-Severe Traumatic Brain Injury: Potential Utility of a Multi-Marker Approach in Characterizing Outcome

(2015) Alex P. Di Battista et al.   Frontiers in Neurology

Oligodendrocyte Birth and Death following Traumatic Brain Injury in Adult Mice

(2015) Krista A. Dent et al.   PLoS One

Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury

(2014) Michelle E. Schober et al.   BRAIN RESEARCH

Postnatal Erythropoietin Mitigates Impaired Cerebral Cortical Development Following Subplate Loss from Prenatal Hypoxia–Ischemia

(2014) Lauren L. Jantzie et al.   CEREBRAL CORTEX

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy

(2014) Susan L. Campbell et al.   GLIA

Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury

(2014) Claudia S. Robertson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association Between Early Administration of High-Dose Erythropoietin in Preterm Infants and Brain MRI Abnormality at Term-Equivalent Age

(2014) Russia Ha-Vinh Leuchter et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Recombinant Human Erythropoietin to Target Cognitive Dysfunction in Bipolar Disorder

(2014) Kamilla W. Miskowiak et al.   JOURNAL OF CLINICAL PSYCHIATRY

NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice

(2014) Jie Xu et al.   Journal of Neuroinflammation

Complex pattern of interaction between in utero hypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function

(2014) Lauren L Jantzie et al.   Journal of Neuroinflammation

The efficacy of erythropoietin in treating experimental traumatic brain injury: a systematic review of controlled trials in animal models

(2014) Weijun Peng et al.   JOURNAL OF NEUROSURGERY

Sex differences in the effect of progesterone after controlled cortical impact in adolescent mice: a preliminary study

(2014) Rebekah Mannix et al.   JOURNAL OF NEUROSURGERY

Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury

(2014) L.L. Jantzie et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Epidemiology of Blunt Head Trauma in Children in U.S. Emergency Departments

(2014) Kimberly S. Quayle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Disability-Adjusted Life-Year Burden of Abusive Head Trauma at Ages 0–4

(2014) Ted R. Miller et al.   PEDIATRICS

Cognitive Outcomes of Preterm Infants Randomized to Darbepoetin, Erythropoietin, or Placebo

(2014) R. K. Ohls et al.   PEDIATRICS

K-Cl cotransporter KCC2—a moonlighting protein in excitatory and inhibitory synapse development and function

(2014) Peter Blaesse et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products

(2014) Zhiqun Zhang et al.   PLoS One

Sociosexual and Communication Deficits after Traumatic Injury to the Developing Murine Brain

(2014) Bridgette D. Semple et al.   PLoS One

Cortical GABAergic excitation contributes to epileptic activities around human glioma

(2014) J. Pallud et al.   Science Translational Medicine

Beneficial effect of amyloid beta after controlled cortical impact

(2013) Rebekah C. Mannix et al.   BRAIN INJURY

Diffusion tensor imaging of hippocampal network plasticity

(2013) Alejandra Sierra et al.   Brain Structure & Function

Biomarkers for the Clinical Differential Diagnosis in Traumatic Brain Injury-A Systematic Review

(2013) Shoji Yokobori et al.   CNS Neuroscience & Therapeutics

Traumatic Injury to the Immature Frontal Lobe: A New Murine Model of Long-Term Motor Impairment in the Absence of Psychosocial or Cognitive Deficits

(2013) Chien-Yi Chen et al.   DEVELOPMENTAL NEUROSCIENCE

Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor

(2013) Sarah C Hellewell et al.   Journal of Neuroinflammation

Erythropoietin Improved Cognitive Function and Decreased Hippocampal Caspase Activity in Rat Pups after Traumatic Brain Injury

(2013) Michelle E. Schober et al.   JOURNAL OF NEUROTRAUMA

Acute Biomarkers of Traumatic Brain Injury: Relationship between Plasma Levels of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein

(2013) Ramon Diaz-Arrastia et al.   JOURNAL OF NEUROTRAUMA

Recombinant Human Erythropoietin for Treating Treatment-Resistant Depression: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial

(2013) Kamilla W Miskowiak et al.   NEUROPSYCHOPHARMACOLOGY

Erythropoietin signaling promotes oligodendrocyte development following prenatal systemic hypoxic–ischemic brain injury

(2013) Lauren L. Jantzie et al.   PEDIATRIC RESEARCH

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature rat

(2012) P. David Adelson et al.   CHILDS NERVOUS SYSTEM

Posttraumatic seizures in children with severe traumatic brain injury

(2012) Jorge I. Arango et al.   CHILDS NERVOUS SYSTEM

N-Methyl-d-aspartate Receptor- and Calpain-mediated Proteolytic Cleavage of K+-Cl−Cotransporter-2 Impairs Spinal Chloride Homeostasis in Neuropathic Pain

(2012) Hong-Yi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-Dependent Cleavage of the K-Cl Cotransporter KCC2 Mediated by Calcium-Activated Protease Calpain

(2012) M. Puskarjov et al.   JOURNAL OF NEUROSCIENCE

Persistence of Disability 24 to 36 Months after Pediatric Traumatic Brain Injury: A Cohort Study

(2012) Frederick P. Rivara et al.   JOURNAL OF NEUROTRAUMA

Outcomes of extremely low birth weight infants given early high-dose erythropoietin

(2012) R M McAdams et al.   Journal of Perinatology

Erythropoietin for Neuroprotection in Neonatal Encephalopathy: Safety and Pharmacokinetics

(2012) Y. W. Wu et al.   PEDIATRICS

Etiological analysis of presumed perinatal stroke

(2011) Canan Kocaman et al.   BRAIN & DEVELOPMENT

Dose-dependent neurorestorative effects of delayed treatment of traumatic brain injury with recombinant human erythropoietin in rats

(2011) Yuling Meng et al.   JOURNAL OF NEUROSURGERY

Detrimental Effect of Genetic Inhibition of B-Site App-Cleaving Enzyme 1 on Functional Outcome after Controlled Cortical Impact in Young Adult Mice

(2011) Rebekah C. Mannix et al.   JOURNAL OF NEUROTRAUMA

Serum Concentrations of Ubiquitin C-Terminal Hydrolase-L1 and αII-Spectrin Breakdown Product 145 kDa Correlate with Outcome after Pediatric TBI

(2011) Rachel P. Berger et al.   JOURNAL OF NEUROTRAUMA

Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival

(2011) Christophe Pellegrino et al.   JOURNAL OF PHYSIOLOGY-LONDON

Age-Dependent Effect of Apolipoprotein E4 on Functional Outcome after Controlled Cortical Impact in Mice

(2010) Rebekah C Mannix et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Loss of Cation-Chloride Cotransporter Expression in Preterm Infants With White Matter Lesions: Implications for the Pathogenesis of Epilepsy

(2010) Shenandoah Robinson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Effects of posttraumatic carbamylated erythropoietin therapy on reducing lesion volume and hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome in rats following traumatic brain injury

(2010) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Prevention of growing skull fractures

(2010) Robert A. Sanford   Journal of Neurosurgery-Pediatrics

Postnatal erythropoietin treatment mitigates neural cell loss after systemic prenatal hypoxic-ischemic injury

(2010) Marcus Mazur et al.   Journal of Neurosurgery-Pediatrics

Traumatic Television Tip-Overs in the Pediatric Patient Population

(2010) John Daniel Rutkoski et al.   JOURNAL OF SURGICAL RESEARCH

Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury

(2010) Pascale Boulenguez et al.   NATURE MEDICINE

Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury

(2010) Bridgette D. Semple et al.   NEUROBIOLOGY OF DISEASE

Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum*

(2010) Douglas D. Fraser et al.   Pediatric Critical Care Medicine

Fractures and Traumatic Brain Injuries: Abuse Versus Accidents in a US Database of Hospitalized Children

(2010) J. M. Leventhal et al.   PEDIATRICS

Recent trends in television tip over-related injuries among children aged 0-9 years

(2009) K J Murray et al.   INJURY PREVENTION

Delayed administration of erythropoietin reducing hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome following traumatic brain injury in rats: comparison of treatment with single and triple dose

(2009) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Imaging biomarkers of outcome in the developing preterm brain

(2009) Laura R Ment et al.   LANCET NEUROLOGY

Prevalence of traumatic brain injury among children, adolescents and young adults: Prospective evidence from a birth cohort

(2008) A. McKinlay et al.   BRAIN INJURY

An Approach to Using Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants

(2008) J.-C. Fauchere et al.   PEDIATRICS

A Phase I/II Trial of High-Dose Erythropoietin in Extremely Low Birth Weight Infants: Pharmacokinetics and Safety

(2008) S. E. Juul et al.   PEDIATRICS

α-Chemokines Regulate Proliferation, Neurogenesis, and Dopaminergic Differentiation of Ventral Midbrain Precursors and Neurospheres

(2008) Linda C. Edman et al.   STEM CELLS