Polymorphism of Kynurenine Pathway-Related Genes, Kynurenic Acid, and Psychopathological Symptoms in HIV

Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications

(2015) Suzi Hong et al.   BRAIN BEHAVIOR AND IMMUNITY

Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression

(2015) Naghmeh Nikkheslat et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered Monoamine and Acylcarnitine Metabolites in HIV-Positive and HIV-Negative Subjects With Depression

(2015) Edana Cassol et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Independent and Co-morbid HIV Infection and Meth Use Disorders on Oxidative Stress Markers in the Cerebrospinal Fluid and Depressive Symptoms

(2015) Jun Panee et al.   Journal of Neuroimmune Pharmacology

Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes

(2015) Isabella Caroline da Silva Dias et al.   MOLECULAR NEUROBIOLOGY

Levels in neurotransmitter precursor amino acids correlate with mental health in patients with breast cancer

(2015) K. Hüfner et al.   PSYCHONEUROENDOCRINOLOGY

The kynurenine pathway and neurodegenerative disease

(2015) Daniel C. Maddison et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

(2015) Mina Elahy et al.   Immunity & Ageing

Disturbed Amino Acid Metabolism in HIV: Association with Neuropsychiatric Symptoms

(2015) Johanna M. Gostner et al.   Frontiers in Psychiatry

Oxidative/Nitrosative Stress and Immuno-inflammatory Pathways in Depression: Treatment Implications

(2014) George Anderson et al.   CURRENT PHARMACEUTICAL DESIGN

The kynurenine pathway is involved in bacterial meningitis

(2014) Leonam G Coutinho et al.   Journal of Neuroinflammation

Kynurenines in CNS disease: regulation by inflammatory cytokines

(2014) Brian M. Campbell et al.   Frontiers in Neuroscience

Serotonin – Kynurenine Hypothesis of Depression: Historical Overview and Recent Developments

(2013) Gregory Oxenkrug   CURRENT DRUG TARGETS

Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine

(2013) Raffaella Molteni et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

d-cycloserine lowers kynurenic acid formation—New mechanism of action

(2013) Halina Baran et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Reversal of the Kynurenine Pathway of Tryptophan Catabolism May Improve Depression in ART-Treated HIV-Infected Ugandans

(2013) Priscilla Martinez et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1 and with increased CSF KYNA level and reduced KMO expression

(2013) C Lavebratt et al.   MOLECULAR PSYCHIATRY

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

(2012) Michael Maes et al.   BMC Medicine

A novel kynurenic acid analog (SZR104) inhibits pentylenetetrazole-induced epileptiform seizures. An electrophysiological study

(2012) Ildikó Demeter et al.   JOURNAL OF NEURAL TRANSMISSION

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Diagnostic classifications in depression and somatization should include biomarkers, such as disorders in the tryptophan catabolite (TRYCAT) pathway

(2012) Michael Maes et al.   PSYCHIATRY RESEARCH

Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis

(2011) Fladjule Rejane Soares de Souza et al.   BMC Medical Genetics

Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder

(2011) M. Elizabeth Sublette et al.   BRAIN BEHAVIOR AND IMMUNITY

The possible role of the kynurenine pathway in anhedonia in adolescents

(2011) Vilma Gabbay et al.   JOURNAL OF NEURAL TRANSMISSION

Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls

(2011) Maria Holtze   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

(2011) Patricia A Zunszain et al.   NEUROPSYCHOPHARMACOLOGY

On the antioxidant properties of kynurenic acid: Free radical scavenging activity and inhibition of oxidative stress

(2011) R. Lugo-Huitrón et al.   NEUROTOXICOLOGY AND TERATOLOGY

The kynurenine pathway in major depression: Haplotype analysis of three related functional candidate genes

(2011) Stephan Claes et al.   PSYCHIATRY RESEARCH

The possible role of the kynurenine pathway in adolescent depression with melancholic features

(2010) Vilma Gabbay et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression

(2010) Michael Maes   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The psychological status of HIV-positive people and their psychosocial experiences in eastern China

(2009) C Jin et al.   HIV MEDICINE

The kynurenate analog SZR-72 prevents the nitroglycerol-induced increase of c-fos immunoreactivity in the rat caudal trigeminal nucleus: Comparative studies of the effects of SZR-72 and kynurenic acid

(2008) E. Knyihar-Csillik et al.   NEUROSCIENCE RESEARCH

HIV and depression: 2008 review and update

(2008) Judith G. Rabkin   Current HIV/AIDS Reports

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE