Acute liver failure impairs function and expression of breast cancer-resistant protein (BCRP) at rat blood-brain barrier partly via ammonia-ROS-ERK1/2 activation

Antiviral therapy for chronic hepatitis B viral infection in adults: A systematic review and meta-analysis

(2015) Anna S.F. Lok et al.   HEPATOLOGY

Effect of cyclosporin on distribution of methotrexate into the brain of rats

(2015) Naofumi OGUSHI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Hippocampus and cerebral cortex present a different autophagic response after oxygen and glucose deprivation in anex vivorat brain slice model

(2015) Diego Pérez-Rodríguez et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The antiepileptic drug lamotrigine is a substrate of mouse and human breast cancer resistance protein (ABCG2)

(2015) Kerstin Römermann et al.   NEUROPHARMACOLOGY

Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress

(2015) Susan A. Austin et al.   PLoS One

Hyperammonemia enhances the function and expression of P-glycoprotein and Mrp2 at the blood-brain barrier through NF-κB

(2014) Ji Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Cerebral effects of ammonia in liver disease: current hypotheses

(2014) Peter Ott et al.   METABOLIC BRAIN DISEASE

Antiapoptotic Actions of Methyl Gallate on Neonatal Rat Cardiac Myocytes Exposed to H2O2

(2014) Sandhya Khurana et al.   Oxidative Medicine and Cellular Longevity

Insulin suppresses the expression and function of breast cancer resistance protein in primary cultures of rat brain microvessel endothelial cells

(2014) Liu Xiang Liu et al.   Pharmacological Reports

ROS and RNS induced apoptosis through p53 and iNOS mediated pathway by a dibasic hydroxamic acid molecule in leukemia cells

(2013) Kaushik Banerjee et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy

(2013) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROCHEMISTRY

Comparative proteome analysis reveals differential regulation of glycolytic and antioxidant enzymes in cortex and hippocampus exposed to short-term hypobaric hypoxia

(2013) Narendra Kumar Sharma et al.   Journal of Proteomics

Aging Induces Tissue-Specific Changes in Cholesterol Metabolism in Rat Brain and Liver

(2013) Kosara Smiljanic et al.   LIPIDS

Ammonia-induced Na,K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling

(2013) Hongliang Dai et al.   NEUROCHEMISTRY INTERNATIONAL

P-glycoprotein and multidrug resistance-associated protein 2 are oppositely altered in brain of rats with thioacetamide-induced acute liver failure

(2012) Shi Jin et al.   LIVER INTERNATIONAL

Oxidative Stress and Blood–Brain Barrier Dysfunction Under Particular Consideration of Matrix Metalloproteinases

(2011) Christine Lehner et al.   ANTIOXIDANTS & REDOX SIGNALING

Microglia activation in hepatic encephalopathy in rats and humans

(2011) Irina Zemtsova et al.   HEPATOLOGY

Neurological complications of acute liver failure: Pathophysiological basis of current management and emerging therapies

(2011) Liliane Mpabanzi et al.   NEUROCHEMISTRY INTERNATIONAL

ABC Transporters and Drug Efflux at the Blood-Brain Barrier

(2011) Shanshan Shen et al.   REVIEWS IN THE NEUROSCIENCES

Role of Breast Cancer Resistance Protein in the Adaptive Response to Cholestasis

(2010) A. Mennone et al.   DRUG METABOLISM AND DISPOSITION

Hyperammonemia Induces Neuroinflammation That Contributes to Cognitive Impairment in Rats With Hepatic Encephalopathy

(2010) Regina Rodrigo et al.   GASTROENTEROLOGY

Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalopathy

(2010) Boris Görg et al.   HEPATOLOGY

Proinflammatory Cytokines Enhance Estrogen-dependent Expression of the Multidrug Transporter GeneABCG2through Estrogen Receptor and NFκB Cooperativity at Adjacent Response Elements

(2010) Madhumita Pradhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute liver failure

(2010) William Bernal et al.   LANCET

Functionally Overlapping Roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the Elimination of Methotrexate and Its Main Toxic Metabolite 7-Hydroxymethotrexate In vivo

(2009) M. L.H. Vlaming et al.   CLINICAL CANCER RESEARCH

The Effect of Breast Cancer Resistance Protein and P-Glycoprotein on the Brain Penetration of Flavopiridol, Imatinib Mesylate (Gleevec), Prazosin, and 2-Methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic Acid (PF-407288) in Mice

(2009) L. Zhou et al.   DRUG METABOLISM AND DISPOSITION

Experimental models of hepatic encephalopathy: ISHEN guidelines

(2009) Roger F. Butterworth et al.   LIVER INTERNATIONAL

Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human

(2009) Mark S. Warren et al.   PHARMACOLOGICAL RESEARCH

ABCG2: A perspective

(2008) Robert W. Robey et al.   ADVANCED DRUG DELIVERY REVIEWS

Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds

(2008) J. Enokizono et al.   DRUG METABOLISM AND DISPOSITION

Ammonia induces RNA oxidation in cultured astrocytes and brainin vivo

(2008) Boris Görg et al.   HEPATOLOGY

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier

(2008) Sandrine Dauchy et al.   JOURNAL OF NEUROCHEMISTRY

Signaling factors in the mechanism of ammonia neurotoxicity

(2008) M. D. Norenberg et al.   METABOLIC BRAIN DISEASE

Human ABC transporters ABCG2 (BCRP) and ABCG4

(2008) S. Koshiba et al.   XENOBIOTICA