ABC Transporters and Drug Efflux at the Blood-Brain Barrier

Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer

(2009) Hilda A. Namanja et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Brain Accumulation of Dasatinib Is Restricted by P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) and Can Be Enhanced by Elacridar Treatment

(2009) J. S. Lagas et al.   CLINICAL CANCER RESEARCH

Breast Cancer Resistance Protein Interacts with Various Compounds in Vitro, but Plays a Minor Role in Substrate Efflux at the Blood-Brain Barrier

(2009) R. Zhao et al.   DRUG METABOLISM AND DISPOSITION

In vitro-in vivo Extrapolation of Transporter-mediated Clearance in the Liver and Kidney

(2009) Hiroyuki Kusuhara et al.   Drug Metabolism and Pharmacokinetics

P-Glycoprotein and Breast Cancer Resistance Protein Restrict Apical-to-Basolateral Permeability of Human Brain Endothelium to Amyloid-β

(2009) Leon M Tai et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential effects of γ-secretase and BACE1 inhibition on brain Aβ levelsin vitroandin vivo

(2009) Anders Brandt Elvang et al.   JOURNAL OF NEUROCHEMISTRY

ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood-Brain Barrier for A 1-40 Peptides

(2009) H. Xiong et al.   JOURNAL OF NEUROSCIENCE

ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS

(2009) M. Daood et al.   NEUROPEDIATRICS

Inhibition of P-glycoprotein function by procyanidine on blood-brain barrier

(2009) Ling He et al.   PHYTOTHERAPY RESEARCH

Competitive Substrates for P-Glycoprotein and Organic Anion Protein Transporters Differentially Reduce Blood Organ Transport of Fentanyl and Loperamide: Pharmacokinetics and Pharmacodynamics in Sprague-Dawley Rats

(2008) Iman A. Elkiweri et al.   ANESTHESIA AND ANALGESIA

Transport of Diclofenac by Breast Cancer Resistance Protein (ABCG2) and Stimulation of Multidrug Resistance Protein 2 (ABCC2)-Mediated Drug Transport by Diclofenac and Benzbromarone

(2008) J. S. Lagas et al.   DRUG METABOLISM AND DISPOSITION

Coordinated Nuclear Receptor Regulation of the Efflux Transporter, Mrp2, and the Phase-Ii Metabolizing Enzyme, GSTπ, at the Blood—Brain Barrier

(2008) Björn Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces

(2008) Silvia Gazzin et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

(2008) Woojin Scott Kim et al.   JOURNAL OF NEUROCHEMISTRY

Changes in dipole membrane potential at the mouse blood-brain barrier enhance the transport of99mTechnetium Sestamibi more than inhibiting Abcb1, Abcc1, or Abcg2

(2008) Julie Cattelotte et al.   JOURNAL OF NEUROCHEMISTRY

P-Glycoprotein Efflux and Other Factors Limit Brain Amyloid   Reduction by  -Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitors in Mice

(2008) J. E. Meredith et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration

(2008) M. Huls et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model

(2008) Babak Nazer et al.   NEUROBIOLOGY OF DISEASE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Subcellular localization of transporters along the rat blood–brain barrier and blood–cerebral-spinal fluid barrier by in vivo biotinylation

(2008) L.M. Roberts et al.   NEUROSCIENCE

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

(2008) Junichi Kamiie et al.   PHARMACEUTICAL RESEARCH

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

(2008) D. S. Miller et al.   PHARMACOLOGICAL REVIEWS

Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules

(2008) F RUSSEL et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Human ABC transporters ABCG2 (BCRP) and ABCG4

(2008) S. Koshiba et al.   XENOBIOTICA

MRP class of human ATP binding cassette (ABC) transporters: historical background and new research directions

(2008) Y. Toyoda et al.   XENOBIOTICA

Antibody-based approaches in Alzheimer’s research: safety, pharmacokinetics, metabolism, and analytical tools

(2007) Peter Lichtlen et al.   JOURNAL OF NEUROCHEMISTRY