BDNF isoforms: a round trip ticket between neurogenesis and serotonin?

Mice lacking the serotonin 5-HT 2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants

(2016) Silvina Laura Diaz et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

MMP-9 in translation: from molecule to brain physiology, pathology, and therapy

(2016) Behnam Vafadari et al.   JOURNAL OF NEUROCHEMISTRY

Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin

(2015) Golo Kronenberg et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

A role for the BDNF gene Val66Met polymorphism in schizophrenia? A comprehensive review

(2015) Michael Notaras et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neurogenesis in the Adult Hippocampus

(2015) Gerd Kempermann et al.   Cold Spring Harbor Perspectives in Biology

Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus

(2015) Yuki Imoto et al.   Molecular Brain

Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus

(2014) Wenyu Cao et al.   BEHAVIOURAL BRAIN RESEARCH

MAPK signaling correlates with the antidepressant effects of ketamine

(2014) Gislaine Z. Réus et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: Insights in depression

(2014) Z.M. Ignácio et al.   NEUROSCIENCE

Association between serum levels of glial cell-line derived neurotrophic factor and attention deficits in schizophrenia

(2014) Tomihisa Niitsu et al.   NEUROSCIENCE LETTERS

Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients

(2014) Reiji Yoshimura et al.   Annals of General Psychiatry

proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus

(2014) Jianmin Yang et al.   Cell Reports

Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin

(2013) Silvina L. Diaz et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Upregulation of blood proBDNF and its receptors in major depression

(2013) Li Zhou et al.   JOURNAL OF AFFECTIVE DISORDERS

Serotonin Is Required for Exercise-Induced Adult Hippocampal Neurogenesis

(2013) F. Klempin et al.   JOURNAL OF NEUROSCIENCE

BDNF and memory processing

(2013) Pedro Bekinschtein et al.   NEUROPHARMACOLOGY

Rapid Anxiolytic Effects of a 5-HT4 Receptor Agonist Are Mediated by a Neurogenesis-Independent Mechanism

(2013) Indira Mendez-David et al.   NEUROPSYCHOPHARMACOLOGY

Effects of repeated 5-HT6 receptor stimulation on BDNF gene expression and cell survival

(2013) Georgina de Foubert et al.   NEUROSCIENCE LETTERS

Reactive Oxygen Species Are Required for 5-HT-Induced Transactivation of Neuronal Platelet-Derived Growth Factor and TrkB Receptors, but Not for ERK1/2 Activation

(2013) Jeff S. Kruk et al.   PLoS One

Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction

(2013) Agustin Anastasia et al.   Nature Communications

The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine

(2013) B D Sachs et al.   Translational Psychiatry

Sex-specific and region-specific changes in BDNF–TrkB signalling in the hippocampus of 5-HT1A receptor and BDNF single and double mutant mice

(2012) YeeWen Candace Wu et al.   BRAIN RESEARCH

Truncated TrkB: Beyond a dominant negative receptor

(2012) Barbara M. Fenner   CYTOKINE & GROWTH FACTOR REVIEWS

Electroconvulsive seizure, but not imipramine, rapidly up-regulates pro-BDNF and t-PA, leading to mature BDNF production, in the rat hippocampus

(2012) Masahiro Segawa et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons

(2012) Sandra Dieni et al.   JOURNAL OF CELL BIOLOGY

BDNF Promotes Differentiation and Maturation of Adult-born Neurons through GABAergic Transmission

(2012) E. G. Waterhouse et al.   JOURNAL OF NEUROSCIENCE

Altered serum content of brain-derived neurotrophic factor isoforms in multiple sclerosis

(2012) Enrico Tongiorgi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation

(2012) S Migliarini et al.   MOLECULAR PSYCHIATRY

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

(2012) Juan Song et al.   NATURE

The impact of the frequency of moderate exercise on memory and brain-derived neurotrophic factor signaling in young adult and middle-aged rats

(2012) M.S. Costa et al.   NEUROSCIENCE

The Responsiveness of TrkB to BDNF and Antidepressant Drugs Is Differentially Regulated during Mouse Development

(2012) Antonio Di Lieto et al.   PLoS One

Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder

(2012) Taisuke Yoshida et al.   PLoS One

Multiple Approaches to Investigate the Transport and Activity-Dependent Release of BDNF and Their Application in Neurogenetic Disorders

(2012) David Hartmann et al.   NEURAL PLASTICITY

Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus

(2011) H. Mizoguchi et al.   JOURNAL OF NEUROSCIENCE

Prenatal stress alters hippocampal synaptic plasticity in young rat offspring through preventing the proteolytic conversion of pro-brain-derived neurotrophic factor (BDNF) to mature BDNF

(2011) Che-Ming Yeh et al.   JOURNAL OF PHYSIOLOGY-LONDON

5-HT2B receptors are required for serotonin-selective antidepressant actions

(2011) S L Diaz et al.   MOLECULAR PSYCHIATRY

Implication of 5-HT2B receptors in the serotonin syndrome

(2011) Silvina Laura Diaz et al.   NEUROPHARMACOLOGY

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

(2011) David Petrik et al.   NEUROPHARMACOLOGY

Exercise influences hippocampal plasticity by modulating brain-derived neurotrophic factor processing

(2011) Q. Ding et al.   NEUROSCIENCE

The antidepressive effect of the physical exercise correlates with increased levels of mature BDNF, and proBDNF proteolytic cleavage-related genes, p11 and tPA

(2011) C.R. Sartori et al.   NEUROSCIENCE

Hippocampal Deletion of BDNF Gene Attenuates Gamma Oscillations in Area CA1 by Up-Regulating 5-HT3 Receptor

(2011) Ying Huang et al.   PLoS One

Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells

(2011) J. L. Swift et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BDNF-TrkB signalling in fear learning: from genetics to neural networks

(2011) Grabiele Musumeci et al.   REVIEWS IN THE NEUROSCIENCES

Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT2C receptor knockout mice

(2010) Rachel A. Hill et al.   HIPPOCAMPUS

Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment

(2010) Marianne H. Larsen et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)

(2010) A. G. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma BDNF and tPA are associated with late-onset geriatric depression

(2010) Yanyan Shi et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Brain-derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions

(2010) Kenji Hashimoto   PSYCHIATRY AND CLINICAL NEUROSCIENCES

The 5-HT7 receptor is involved in allocentric spatial memory information processing

(2009) Gor Sarkisyan et al.   BEHAVIOURAL BRAIN RESEARCH

Early raise of BDNF in hippocampus suggests induction of posttranscriptional mechanisms by antidepressants

(2009) Laura Musazzi et al.   BMC NEUROSCIENCE

Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation

(2009) Grace Sophia Griesbach et al.   BRAIN RESEARCH

Role of Brain-Derived Neurotrophic Factor in the Aetiology of Depression

(2009) Eero Castrén et al.   CNS DRUGS

A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain

(2009) Daniela Popa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review

(2009) Alain M. Gardier et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Adult-Born Hippocampal Neurons Are More Numerous, Faster Maturing, and More Involved in Behavior in Rats than in Mice

(2009) J. S. Snyder et al.   JOURNAL OF NEUROSCIENCE

Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update

(2009) Volkmar Leßmann et al.   NEUROSCIENCE RESEARCH

Control of extracellular cleavage of ProBDNF by high frequency neuronal activity

(2009) G. Nagappan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The When and Where of BDNF and the Antidepressant Response

(2008) Jing-Wen Wang et al.   BIOLOGICAL PSYCHIATRY

Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

(2008) Srijan Sen et al.   BIOLOGICAL PSYCHIATRY

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

Efficient copackaging and cotransport yields postsynaptic colocalization of neuromodulators associated with synaptic plasticity

(2008) J.E. Lochner et al.   Developmental Neurobiology

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

(2008) André Russowsky Brunoni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment

(2008) Yun Li et al.   NEURON

Acute Stress Responsiveness of the Neurotrophin BDNF in the Rat Hippocampus is Modulated by Chronic Treatment with the Antidepressant Duloxetine

(2008) Raffaella Molteni et al.   NEUROPSYCHOPHARMACOLOGY

S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

(2008) Anne Dekeyne et al.   PSYCHOPHARMACOLOGY

Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy

(2007) Megumi Adachi et al.   BIOLOGICAL PSYCHIATRY

Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: Studies in adult mice hippocampus

(2007) Thierry Deltheil et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR