Kinesin-2 motors differentially impact biogenesis of extracellular vesicle subpopulations shed from sensory cilia

Isolation, profiling, and tracking of extracellular vesicle cargo in Caenorhabditis elegans

(2022) Inna A. Nikonorova et al.   CURRENT BIOLOGY

Emerging Roles of Extracellular Vesicles in the Central Nervous System: Physiology, Pathology, and Therapeutic Perspectives

(2021) Yadaly Gassama et al.   Frontiers in Cellular Neuroscience

Conserved role of ATP synthase in mammalian cilia

(2021) Wenjun Lin et al.   EXPERIMENTAL CELL RESEARCH

Role of ATP in Extracellular Vesicle Biogenesis and Dynamics

(2021) Marta Lombardi et al.   Frontiers in Pharmacology

Sensory cilia act as a specialized venue for regulated extracellular vesicle biogenesis and signaling

(2021) Juan Wang et al.   CURRENT BIOLOGY

Ectocytosis prevents accumulation of ciliary cargo in C. elegans sensory neurons

(2021) Adria Razzauti et al.   eLife

Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles

(2021) Ann-Kathrin Volz et al.   Nature Communications

Structure and activation mechanism of the BBSome membrane protein trafficking complex

(2020) Sandeep K Singh et al.   eLife

Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding

(2020) Jyothi S Akella et al.   eLife

Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy

(2020) Jack Taylor et al.   Journal of Extracellular Vesicles

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Release and targeting of polycystin-2-carrying ciliary extracellular vesicles

(2020) Juan Wang et al.   CURRENT BIOLOGY

Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies

(2020) Kanae Demura et al.   Science Advances

Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging

(2020) Joshua C. Russell et al.   GeroScience

Ciliary Tip Signaling Compartment Is Formed and Maintained by Intraflagellar Transport

(2020) Servaas N. van der Burght et al.   CURRENT BIOLOGY

A Rapid, SuperSelective Method for Detection of Single Nucleotide Variants in Caenorhabditis elegans

(2020) Denis Touroutine et al.   GENETICS

Interpreting the pathogenicity of Joubert syndrome missense variants in Caenorhabditis elegans

(2020) Karen I. Lange et al.   Disease Models & Mechanisms

Cooperation of the IFT-A complex with the IFT-B complex is required for ciliary retrograde protein trafficking and GPCR import

(2020) Takuya Kobayashi et al.   MOLECULAR BIOLOGY OF THE CELL

Direct visualization of cAMP signaling in primary cilia reveals up-regulation of ciliary GPCR activity following Hedgehog activation

(2019) Jason Y. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes

(2018) Zhongming Ma et al.   NEURON

Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery

(2017) Bram Prevo et al.   FEBS Journal

Ethanol Stimulates Locomotion via a Gαs-Signaling Pathway in IL2 Neurons inCaenorhabditis elegans

(2017) James R. Johnson et al.   GENETICS

Plasma membrane-derived extracellular microvesicles mediate non-canonical intercellular NOTCH signaling

(2017) Qiyu Wang et al.   Nature Communications

Ethanol Stimulates Locomotion via a Gαs-Signaling Pathway in IL2 Neurons inCaenorhabditis elegans

(2017) James R. Johnson et al.   GENETICS

The CALHM1 P86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer's Disease: a Meta-Analysis Study

(2017) Jean-Charles Lambert et al.   JOURNAL OF ALZHEIMERS DISEASE

Ciliary Extracellular Vesicles: Txt Msg Organelles

(2016) Juan Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice

(2016) Valérie Vingtdeux et al.   Scientific Reports

PROS-1/Prospero Is a Major Regulator of the Glia-Specific Secretome Controlling Sensory-Neuron Shape and Function in C. elegans

(2016) Sean W. Wallace et al.   Cell Reports

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

(2016) Chunmei Li et al.   PLOS BIOLOGY

Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis

(2015) Juan Wang et al.   CURRENT BIOLOGY

Formation of the transition zone by Mks5/Rpgrip1L establishes a ciliary zone of exclusion (CIZE) that compartmentalises ciliary signalling proteins and controls PIP2 ciliary abundance

(2015) V. L. Jensen et al.   EMBO JOURNAL

Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis

(2015) Julie E. Maguire et al.   MOLECULAR BIOLOGY OF THE CELL

Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia

(2015) Bram Prevo et al.   NATURE CELL BIOLOGY

C. elegans Ciliated Sensory Neurons Release Extracellular Vesicles that Function in Animal Communication

(2014) Juan Wang et al.   CURRENT BIOLOGY

Diverse Cell Type-Specific Mechanisms Localize G Protein-Coupled Receptors to Caenorhabditis elegans Sensory Cilia

(2014) Andrea G. Brear et al.   GENETICS

Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon

(2014) Christian Frøkjær-Jensen et al.   NATURE METHODS

Compartments within a compartment

(2014) Oliver E Blacque et al.   Organogenesis

A high-resolution morphological and ultrastructural map of anterior sensory cilia and glia in Caenorhabditis elegans

(2014) David B Doroquez et al.   eLife

Regulated Membrane Protein Entry into Flagella Is Facilitated by Cytoplasmic Microtubules and Does Not Require IFT

(2013) Olivier Belzile et al.   CURRENT BIOLOGY

The Cilium Secretes Bioactive Ectosomes

(2013) Christopher R. Wood et al.   CURRENT BIOLOGY

CLHM-1 is a Functionally Conserved and Conditionally Toxic Ca2+-Permeable Ion Channel in Caenorhabditis elegans

(2013) J. E. Tanis et al.   JOURNAL OF NEUROSCIENCE

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

(2013) Akiyuki Taruno et al.   NATURE

Primary cilia are specialized calcium signalling organelles

(2013) Markus Delling et al.   NATURE

Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia

(2013) Alexander V. Loktev et al.   Cell Reports

Endocytosis Genes Facilitate Protein and Membrane Transport in C. elegans Sensory Cilia

(2012) Oktay I. Kaplan et al.   CURRENT BIOLOGY

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

(2012) Z. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin-3 KLP-6 Regulates Intraflagellar Transport in Male-Specific Cilia of Caenorhabditis elegans

(2011) Natalia S. Morsci et al.   CURRENT BIOLOGY

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL