Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers
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Title
Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers
Authors
Keywords
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Journal
Biomolecules
Volume 12, Issue 11, Pages 1581
Publisher
MDPI AG
Online
2022-10-30
DOI
10.3390/biom12111581
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- (2022) Qi Liu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2022) Zhipeng Li et al. Nature Chemical Biology
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- (2022) Yangjing Zhao et al. Cancers
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- (2022) Yijia Yang et al. Antioxidants
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- (2022) Kamari Weaver et al. Biomedicines
- The Role of Selenoproteins SELENOM and SELENOT in the Regulation of Apoptosis, ER Stress, and Calcium Homeostasis in the A-172 Human Glioblastoma Cell Line
- (2022) Elena G. Varlamova et al. Biology-Basel
- Thioredoxin Signaling Pathways in Cancer
- (2022) Junmin Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6
- (2022) Didac Santesmasses et al. Biomolecules
- Advances in Research on the Toxicological Effects of Selenium
- (2021) Qizhuang Lv et al. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
- Colonic epithelial-derived Selenoprotein P is the source for antioxidant-mediated protection in colitis-associated cancer
- (2021) Sarah P. Short et al. GASTROENTEROLOGY
- A pan-cancer study of selenoprotein genes as promising targets for cancer therapy
- (2021) Wentao Wu et al. BMC Medical Genomics
- Obesity, Type 2 Diabetes, and Cancer Risk
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- (2021) Namgyu Lee et al. Antioxidants
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- A novel cystathionine γ-lyase inhibitor, I194496, inhibits the growth and metastasis of human TNBC via downregulating multiple signaling pathways
- (2021) Ya Liu et al. Scientific Reports
- Cystathionine Gamma-Lyase Is Increased in Testicular Seminomas, Embryonal, and Yolk Sac Tumors
- (2021) EKIN OZLUK et al. ANTICANCER RESEARCH
- The Hidden Role of Hydrogen Sulfide Metabolism in Cancer
- (2021) Rong-Hsuan Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- THE MAIN CYTOTOXIC EFFECTS OF METHYLSELENINIC ACID ON VARIOUS CANCER CELLS
- (2021) Elena G. Varlamova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanisms of the Cytotoxic Effect of Selenium Nanoparticles in Different Human Cancer Cell Lines
- (2021) Elena G. Varlamova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of Thioredoxin Reductase by Santamarine Conferring Anticancer Effect in HeLa Cells
- (2021) Junmin Zhang et al. Frontiers in Molecular Biosciences
- Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
- (2021) Rannapaula Lawrynhuk Urbano Ferreira et al. Frontiers in Nutrition
- Metabolism of Tracer 75Se Selenium From Inorganic and Organic Selenocompounds Into Selenoproteins in Rats, and the Missing 75Se Metabolites
- (2021) Jacqueline K. Evenson et al. Frontiers in Nutrition
- Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer
- (2021) Marina Delgobo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity
- (2021) Jessica A. Canter et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Selenotranscriptome Network in Non-alcoholic Fatty Liver Disease
- (2021) Kaitlin Day et al. Frontiers in Nutrition
- Accessing the transcriptional status of selenoproteins in skin cancer-derived cell lines
- (2020) Assis Ecker et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Involvement of glutathione peroxidases in the occurrence and development of breast cancers
- (2020) Man-Li Zhang et al. Journal of Translational Medicine
- Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer
- (2020) Caroline Chang et al. Cancers
- Expression of ER-resident selenoproteins and activation of cancer cells apoptosis mechanisms under ER-stress conditions caused by methylseleninic acid
- (2020) M.V. Goltyaev et al. GENE
- Role of Glutathione in Cancer: From Mechanisms to Therapies
- (2020) Luke Kennedy et al. Biomolecules
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- (2019) Zahra Ghanbari Movahed et al. BIOMEDICINE & PHARMACOTHERAPY
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- Targeting the Thioredoxin System as a Strategy for Cancer Therapy
- (2019) Mianli Bian et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2019) Herena Y. Ha et al. BIOLOGICAL TRACE ELEMENT RESEARCH
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- (2019) Lupeng Wang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
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- (2019) Yi‐Hsiang Wang et al. EMBO REPORTS
- Selenium intake, status, and health: a complex relationship
- (2019) Margaret P Rayman Hormones-International Journal of Endocrinology and Metabolism
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- Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines
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- (2018) Needa A. Virani et al. CANCER LETTERS
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- Selenium and GPX4, a vital symbiosis
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- The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
- (2018) Heike Miess et al. ONCOGENE
- Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition
- (2018) Qiang He et al. Oxidative Medicine and Cellular Longevity
- Cystathionine β-Synthase in Physiology and Cancer
- (2018) Haoran Zhu et al. Biomed Research International
- Role of GPX4 in ferroptosis and its pharmacological implication
- (2018) Tobias M. Seibt et al. FREE RADICAL BIOLOGY AND MEDICINE
- Metabolic Syndrome and the Risk of Breast Cancer and Subtypes by Race, Menopause and BMI
- (2018) Daniel Dibaba et al. Cancers
- Induction of Oxidative Stress via Inhibition of Thioredoxin Reductase 1 is an Effective Therapeutic Approach for Hepatocellular Carcinoma
- (2018) Derek Lee et al. HEPATOLOGY
- Burden of cancer attributable to obesity, type 2 diabetes and associated risk factors
- (2018) Alejandro López-Suárez METABOLISM-CLINICAL AND EXPERIMENTAL
- I157172, a novel inhibitor of cystathionine γ-lyase, inhibits growth and migration of breast cancer cells via SIRT1-mediated deacetylation of STAT3
- (2018) Lupeng Wang et al. ONCOLOGY REPORTS
- GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation
- (2018) Qingcai Meng et al. Cell Death & Disease
- Expression of Selenoprotein Genes and Association with Selenium Status in Colorectal Adenoma and Colorectal Cancer
- (2018) David Hughes et al. Nutrients
- PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway
- (2018) Lin Tuo et al. Frontiers in Oncology
- Inhibition of TrxR2 suppressed NSCLC cell proliferation, metabolism and induced cell apoptosis through decreasing antioxidant activity
- (2017) Lina Bu et al. LIFE SCIENCES
- A pathology atlas of the human cancer transcriptome
- (2017) Mathias Uhlen et al. SCIENCE
- Targeting the Thioredoxin System for Cancer Therapy
- (2017) Junmin Zhang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway
- (2017) Jing You et al. Oncotarget
- Glutathione peroxidases as oncotargets
- (2017) Yang Jiao et al. Oncotarget
- TXNRD1 Is an Unfavorable Prognostic Factor for Patients with Hepatocellular Carcinoma
- (2017) Binsheng Fu et al. Biomed Research International
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- (2017) Claudia Tonelli et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2016) Loubna Boukhzar et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2016) Elena Buzzetti et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- A study on the structural features of SELK, an over-expressed protein in hepatocellular carcinoma, by molecular dynamics simulations in a lipid–water system
- (2016) Andrea Polo et al. Molecular BioSystems
- Up Regulation of cystathione γ lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol–Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats
- (2016) Ashfaq Ahmad et al. PLoS One
- Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis
- (2015) Juliane Hellfritsch et al. ANTIOXIDANTS & REDOX SIGNALING
- The Association Between Serum Levels of Selenium, Copper, and Magnesium with Thyroid Cancer: a Meta-analysis
- (2015) Fei Shen et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Role of cystathionine β-synthase in human breast Cancer
- (2015) Suvajit Sen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Adult Weight Gain and Adiposity-Related Cancers: A Dose-Response Meta-Analysis of Prospective Observational Studies
- (2015) NaNa Keum et al. JNCI-Journal of the National Cancer Institute
- Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition
- (2015) Míriam Tarrado-Castellarnau et al. PHARMACOLOGICAL RESEARCH
- Adult Weight Gain and Adiposity-Related Cancers: A Dose-Response Meta-Analysis of Prospective Observational Studies
- (2015) NaNa Keum et al. JNCI-Journal of the National Cancer Institute
- The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways
- (2015) Petra A. Tsuji et al. PLoS One
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Hepatic metabolite profiles in mice with a suboptimal selenium status
- (2014) Kerstin E. Geillinger et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults
- (2014) Krishnan Bhaskaran et al. LANCET
- Hydrogen sulfide (H2S)/cystathionine γ-lyase (CSE) pathway contributes to the proliferation of hepatoma cells
- (2014) Yan Pan et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Selenoproteins: Molecular Pathways and Physiological Roles
- (2014) Vyacheslav M. Labunskyy et al. PHYSIOLOGICAL REVIEWS
- Regulation of the pentose phosphate pathway in cancer
- (2014) Peng Jiang et al. Protein & Cell
- Nox1 causes ileocolitis in mice deficient in glutathione peroxidase-1 and -2
- (2013) Robert S. Esworthy et al. FREE RADICAL BIOLOGY AND MEDICINE
- Role of Glutathione in Cancer Progression and Chemoresistance
- (2013) Nicola Traverso et al. Oxidative Medicine and Cellular Longevity
- Correction: A Low Selenium Level Is Associated with Lung and Laryngeal Cancers
- (2013) Katrzyna Jaworska et al. PLoS One
- Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance
- (2013) Sanjib Bhattacharyya et al. PLoS One
- Tumor-derived hydrogen sulfide, produced by cystathionine- -synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer
- (2013) C. Szabo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2012) Regina Brigelius-Flohé et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Glutathione levels in human tumors
- (2012) Michael P. Gamcsik et al. BIOMARKERS
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Metabolic Syndrome and Risk of Cancer: A systematic review and meta-analysis
- (2012) K. Esposito et al. DIABETES CARE
- β-Catenin Regulates Deiodinase Levels and Thyroid Hormone Signaling in Colon Cancer Cells
- (2012) Monica Dentice et al. GASTROENTEROLOGY
- Long Isoform Mouse Selenoprotein P (Sepp1) Supplies Rat Myoblast L8 Cells with Selenium via Endocytosis Mediated by Heparin Binding Properties and Apolipoprotein E Receptor-2 (ApoER2)
- (2012) Suguru Kurokawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selenium and human health
- (2012) Margaret P Rayman LANCET
- Disruption of the Selenocysteine Lyase-Mediated Selenium Recycling Pathway Leads to Metabolic Syndrome in Mice
- (2012) L. A. Seale et al. MOLECULAR AND CELLULAR BIOLOGY
- Characterization of Hydrogen Sulfide and Its Synthases, Cystathionine β-Synthase and Cystathionine γ-Lyase, in Human Prostatic Tissue and Cells
- (2012) Hui Guo et al. UROLOGY
- Molecular cloning, chromosomal localization and expression profiling of porcine selenoprotein M gene
- (2011) Ji-Chang Zhou et al. Genes & Genomics
- Vitamin E and the Risk of Prostate Cancer
- (2011) Eric A. Klein et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mammalian Selenocysteine Lyase Is Involved in Selenoprotein Biosynthesis
- (2011) Suguru KUROKAWA et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Antioxidant and Anticancer Properties and Mechanisms of Inorganic Selenium, Oxo-Sulfur, and Oxo-Selenium Compounds
- (2010) Ria R. Ramoutar et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- System xc−and Thioredoxin Reductase 1 Cooperatively Rescue Glutathione Deficiency
- (2010) Pankaj Kumar Mandal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Redox Regulation of Cell Survival by the Thioredoxin Superfamily: An Implication of Redox Gene Therapy in the Heart
- (2009) Md. Kaimul Ahsan et al. ANTIOXIDANTS & REDOX SIGNALING
- Selenium Status and the Risk of Esophageal and Gastric Cancer Subtypes: The Netherlands Cohort Study
- (2009) Jessie Steevens et al. GASTROENTEROLOGY
- Extracellular thiol-assisted selenium uptake dependent on the xc- cystine transporter explains the cancer-specific cytotoxicity of selenite
- (2009) E. Olm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum Selenium Levels and All-Cause, Cancer, and Cardiovascular Mortality Among US Adults
- (2008) Joachim Bleys ARCHIVES OF INTERNAL MEDICINE
- Increased levels of superoxide and H2O2mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation
- (2008) Nùkhet Aykin-Burns et al. BIOCHEMICAL JOURNAL
- Selenium status highly regulates selenoprotein mRNA levels for only a subset of the selenoproteins in the selenoproteome
- (2008) Roger A. Sunde et al. BIOSCIENCE REPORTS
- Food-chain selenium and human health: spotlight on speciation
- (2008) Margaret P. Rayman et al. BRITISH JOURNAL OF NUTRITION
- Glutathione peroxidase family - an evolutionary overview
- (2008) Rogerio Margis et al. FEBS Journal
- Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
- (2008) Andrew G Renehan et al. LANCET
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