Conoid extrusion regulates glideosome assembly to control motility and invasion in Apicomplexa

Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation

(2022) Lorenzo Brusini et al.   JOURNAL OF CELL BIOLOGY

An apical protein, Pcr2, is required for persistent movement by the human parasite Toxoplasma gondii

(2022) Jonathan Munera Lopez et al.   PLoS Pathogens

Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid

(2021) Eloïse Bertiaux et al.   PLOS BIOLOGY

Molecular characterization of the conoid complex in Toxoplasma reveals its conservation in all apicomplexans, including Plasmodium species

(2021) Ludek Koreny et al.   PLOS BIOLOGY

Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems

(2021) Ellie I. James et al.   CHEMICAL REVIEWS

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems

(2021) Shrawan Kumar Mageswaran et al.   Nature Communications

Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion

(2021) Gaëlle Lentini et al.   Nature Communications

Revisiting the Role of Toxoplasma gondii ERK7 in the Maintenance and Stability of the Apical Complex

(2021) Nicolas Dos Santos Pacheco et al.   mBio

IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

(2020) Bui Quang Minh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Coupling Polar Adhesion with Traction, Spring and Torque Forces Allows High Speed Helical Migration of the Protozoan Parasite Toxoplasma

(2020) Georgios Pavlou et al.   ACS Nano

Evolution, Composition, Assembly, and Function of the Conoid in Apicomplexa

(2020) Nicolas Dos Santos Pacheco et al.   TRENDS IN PARASITOLOGY

Essential function of the alveolin network in the subpellicular microtubules and conoid assembly in Toxoplasma gondii

(2020) Nicolò Tosetti et al.   eLife

A Comprehensive Subcellular Atlas of the Toxoplasma Proteome via hyperLOPIT Provides Spatial Context for Protein Functions

(2020) Konstantin Barylyuk et al.   Cell Host & Microbe

The Biology of the Intestinal Intracellular Parasite Cryptosporidium

(2020) Amandine Guérin et al.   Cell Host & Microbe

Phylogenomics identifies a new major subgroup of apicomplexans, Marosporida class. nov., with extreme apicoplast genome reduction

(2020) Varsha Mathur et al.   Genome Biology and Evolution

Biogenesis and discharge of the rhoptries: Key organelles for entry and hijack of host cells by the Apicomplexa

(2020) Rouaa Ben Chaabene et al.   MOLECULAR MICROBIOLOGY

Phosphatidic acid governs natural egress in Toxoplasma gondii via a guanylate cyclase receptor platform

(2019) Hugo Bisio et al.   Nature Microbiology

Biogenesis and secretion of micronemes in Toxoplasma gondii

(2019) David J. Dubois et al.   CELLULAR MICROBIOLOGY

Three F-actin assembly centers regulate organelle inheritance, cell-cell communication and motility in Toxoplasma gondii

(2019) Nicolò Tosetti et al.   eLife

Centrin2 from the human parasite Toxoplasma gondii is required for its invasion and intracellular replication

(2019) Jacqueline M. Leung et al.   JOURNAL OF CELL SCIENCE

The roles of Centrin 2 and Dynein Light Chain 8a in apical secretory organelles discharge of Toxoplasma gondii

(2019) Gaëlle Lentini et al.   TRAFFIC

Multiple Independent Origins of Apicomplexan-Like Parasites

(2019) Varsha Mathur et al.   CURRENT BIOLOGY

Apicomplexan-like parasites are polyphyletic and widely but selectively dependent on cryptic plastid organelles

(2019) Jan Janouškovec et al.   eLife

Toxoplasma Parasite Twisting Motion Mechanically Induces Host Cell Membrane Fission to Complete Invasion within a Protective Vacuole

(2018) Georgios Pavlou et al.   Cell Host & Microbe

Metal binding properties, stability and reactivity of zinc fingers

(2018) Katarzyna Kluska et al.   COORDINATION CHEMISTRY REVIEWS

Toxoplasma gondii TFP1 is an essential transporter family protein critical for microneme maturation and exocytosis

(2018) Pierre-Mehdi Hammoudi et al.   MOLECULAR MICROBIOLOGY

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

(2018) Min Zhang et al.   SCIENCE

Calcium signaling and the lytic cycle of the Apicomplexan parasite Toxoplasma gondii

(2018) Miryam Andrea Hortua Triana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A systematic review on modelling approaches for economic losses studies caused by parasites and their associated diseases in cattle

(2018) Muhammad Rashid et al.   PARASITOLOGY

Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites

(2018) Hanwei Fang et al.   Nature Communications

Loss of a doublecortin (DCX)-domain protein causes structural defects in a tubulin-based organelle of Toxoplasma gondii and impairs host-cell invasion

(2017) Eiji Nagayasu et al.   MOLECULAR BIOLOGY OF THE CELL

Stability and function of a putative microtubule-organizing center in the human parasite Toxoplasma gondii

(2017) Jacqueline M. Leung et al.   MOLECULAR BIOLOGY OF THE CELL

Gliding motility powers invasion and egress in Apicomplexa

(2017) Karine Frénal et al.   NATURE REVIEWS MICROBIOLOGY

Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii

(2017) Kevin M. Brown et al.   mBio

A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii

(2017) Shaojun Long et al.   Nature Communications

Malaria

(2017) Margaret A. Phillips et al.   Nature Reviews Disease Primers

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

(2016) Saima M. Sidik et al.   CELL

An Apicomplexan Actin-Binding Protein Serves as a Connector and Lipid Sensor to Coordinate Motility and Invasion

(2016) Damien Jacot et al.   Cell Host & Microbe

SAS6-like protein in Plasmodium indicates that conoid-associated apical complex proteins persist in invasive stages within the mosquito vector

(2016) Richard J. Wall et al.   Scientific Reports

The Conoid Associated Motor MyoH Is Indispensable for Toxoplasma gondii Entry and Exit from Host Cells

(2016) Arnault Graindorge et al.   PLoS Pathogens

Identification of Potent Phosphodiesterase Inhibitors that Demonstrate Cyclic Nucleotide-Dependent Functions in Apicomplexan Parasites

(2015) Brittany L. Howard et al.   ACS Chemical Biology

Plasticity between MyoC- and MyoA-Glideosomes: An Example of Functional Compensation in Toxoplasma gondii Invasion

(2014) Karine Frénal et al.   PLoS Pathogens

Electron tomography ofPlasmodium falciparummerozoites reveals core cellular events that underpin erythrocyte invasion

(2013) Eric Hanssen et al.   CELLULAR MICROBIOLOGY

A SAS-6-Like Protein Suggests that the Toxoplasma Conoid Complex Evolved from Flagellar Components

(2013) Jessica Cruz de Leon et al.   EUKARYOTIC CELL

Identification of functional modules of AKMT, a novel lysine methyltransferase regulating the motility of Toxoplasma gondii

(2013) Senthilkumar Sivagurunathan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A Plasmodium Calcium-Dependent Protein Kinase Controls Zygote Development and Transmission by Translationally Activating Repressed mRNAs

(2012) Sarah Sebastian et al.   Cell Host & Microbe

Evolution of apicomplexan secretory organelles

(2012) Marc-Jan Gubbels et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility

(2011) Eliane C. Laurentino et al.   CELLULAR MICROBIOLOGY

phytools: an R package for phylogenetic comparative biology (and other things)

(2011) Liam J. Revell   Methods in Ecology and Evolution

The Motility of a Human Parasite, Toxoplasma gondii, Is Regulated by a Novel Lysine Methyltransferase

(2011) Aoife T. Heaslip et al.   PLoS Pathogens

A Systematic Screen to Discover and Analyze Apicoplast Proteins Identifies a Conserved and Essential Protein Import Factor

(2011) Lilach Sheiner et al.   PLoS Pathogens

RNG1 is a late marker of the apical polar ring in Toxoplasma gondii

(2010) Johnson Q. Tran et al.   Cytoskeleton

Concerted Action of Two Formins in Gliding Motility and Host Cell Invasion by Toxoplasma gondii

(2010) Wassim Daher et al.   PLoS Pathogens

A Novel Family of Toxoplasma IMC Proteins Displays a Hierarchical Organization and Functions in Coordinating Parasite Division

(2010) Josh R. Beck et al.   PLoS Pathogens

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Induction and regulation of conoid extrusion inToxoplasma gondii

(2009) M. González Del Carmen et al.   CELLULAR MICROBIOLOGY

TgICMAP1 Is a Novel Microtubule Binding Protein in Toxoplasma gondii

(2009) Aoife T. Heaslip et al.   PLoS One

A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite

(2009) Robert W. Moon et al.   PLoS Pathogens

Export of a Toxoplasma gondii Rhoptry Neck Protein Complex at the Host Cell Membrane to Form the Moving Junction during Invasion

(2009) Sébastien Besteiro et al.   PLoS Pathogens

A Malaria Parasite Formin Regulates Actin Polymerization and Localizes to the Parasite-Erythrocyte Moving Junction during Invasion

(2008) Jake Baum et al.   Cell Host & Microbe

Toxoplasma Profilin Is Essential for Host Cell Invasion and TLR11-Dependent Induction of an Interleukin-12 Response

(2008) Fabienne Plattner et al.   Cell Host & Microbe