The endoplasmic reticulum membrane protein Sec62 as potential therapeutic target in SEC62 overexpressing tumors
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The endoplasmic reticulum membrane protein Sec62 as potential therapeutic target in SEC62 overexpressing tumors
Authors
Keywords
-
Journal
Frontiers in Physiology
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-10-03
DOI
10.3389/fphys.2022.1014271
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sec62 promotes gastric cancer metastasis through mediating UPR-induced autophagy activation
- (2022) Song Su et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The broad range di- and trinucleotide exchanger SLC35B1 displays asymmetrical affinities for ATP transport across the ER membrane
- (2022) Pablo J. Schwarzbaum et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hallmarks of Cancer: New Dimensions
- (2022) Douglas Hanahan Cancer Discovery
- PKC Inhibits Sec61 Translocon-Mediated Sarcoplasmic Reticulum Ca2+ Leak in Smooth Muscle Cells
- (2022) Adan Dagnino-Acosta et al. Frontiers in Physiology
- Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import
- (2022) Sven Lang et al. Frontiers in Physiology
- Antagonizing Sec62 function in intracellular Ca2+ homeostasis represents a novel therapeutic strategy for head and neck cancer
- (2022) Sandrina Körner et al. Frontiers in Physiology
- SEC62 and SEC63 Expression in Hepatocellular Carcinoma and Tumor-Surrounding Liver Tissue
- (2021) Markus Casper et al. Visceral Medicine
- Sec62 promotes stemness and chemoresistance of human colorectal cancer through activating Wnt/β-catenin pathway
- (2021) Xiaofeng Liu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- SEC61G is upregulated and required for tumor progression in human kidney cancer
- (2021) Hui Meng et al. Molecular Medicine Reports
- Expression of SEC62 Oncogene in Benign, Malignant and Borderline Melanocytic Tumors—Unmasking the Wolf in Sheep’s Clothing?
- (2021) Cornelia S. L. Müller et al. Cancers
- Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex
- (2021) Mark Sicking et al. Cells
- Sec62 promotes pro-angiogenesis of hepatocellular carcinoma cells under hypoxia
- (2021) Yongbin Meng et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Cancer associated mutations in Sec61γ alter the permeability of the ER translocase
- (2021) Christopher M. Witham et al. PLoS Genetics
- Identification of signal peptide features for substrate specificity in human Sec62/Sec63‐dependent ER protein import
- (2020) Stefan Schorr et al. FEBS Journal
- ER-phagy: Eating the Factory
- (2020) Maurizio Molinari MOLECULAR CELL
- A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
- (2020) Xia Li et al. Cell Reports
- Sec62/Ki67 and p16/Ki67 dual-staining immunocytochemistry in vulvar cytology for the identification of vulvar intraepithelial neoplasia and vulvar cancer: a pilot study
- (2019) Ferenc Zoltan Takacs et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- The signal peptide plus a cluster of positive charges in prion protein dictate chaperone-mediated Sec61 channel gating
- (2019) Anke Ziska et al. Biology Open
- Identification of 3q oncogene SEC62 as a marker for distant metastasis and poor clinical outcome in invasive ductal breast cancer
- (2019) Ferenc Zoltan Takacs et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Identification of SEC61G as a Novel Prognostic Marker for Predicting Survival and Response to Therapies in Patients with Glioblastoma
- (2019) Bo Liu et al. MEDICAL SCIENCE MONITOR
- ER import of small human presecretory proteins: components and mechanisms
- (2019) Sarah Haßdenteufel et al. FEBS LETTERS
- Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2+
- (2019) Jing Yong et al. eLife
- Etiology-Specific Analysis of Hepatocellular Carcinoma Transcriptome Reveals Genetic Dysregulation in Pathways Implicated in Immunotherapy Efficacy
- (2019) Wei Tse Li et al. Cancers
- MiR-4429 prevented gastric cancer progression through targeting METTL3 to inhibit m6A-caused stabilization of SEC62
- (2019) Huabo He et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
- (2019) Marisa Loi et al. Nature Communications
- Sec62 promotes early recurrence of hepatocellular carcinoma through activating integrinα/CAV1 signalling
- (2019) Juan Du et al. Oncogenesis
- Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier
- (2018) Sarah Haßdenteufel et al. Cell Reports
- AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
- (2018) Marie-Christine Klein et al. Nature Communications
- Sec62/Ki67 dual staining in cervical cytology specimens: a new marker for high-grade dysplasia
- (2018) Ferenc Zoltan Takacs et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Expression of 3q oncogene SEC62 in atypical fibroxanthoma‑immunohistochemical analysis of 41 cases and correlation with clinical, viral and histopathologic features
- (2018) Cornelia M�ller et al. Oncology Letters
- The Sec61 translocon limits IRE1α signaling during the unfolded protein response
- (2017) Arunkumar Sundaram et al. eLife
- An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases
- (2017) Sven Lang et al. Frontiers in Physiology
- Identification of SEC62 as a potential marker for 3q amplification and cellular migration in dysplastic cervical lesions
- (2016) Maximilian Linxweiler et al. BMC CANCER
- Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours
- (2016) D Mahalingam et al. BRITISH JOURNAL OF CANCER
- Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
- (2016) Fiorenza Fumagalli et al. NATURE CELL BIOLOGY
- Five Questions (with their Answers) on ER-Associated Degradation
- (2016) Giorgia Brambilla Pisoni et al. TRAFFIC
- Initial evidence for Sec62 as a prognostic marker in advanced head and neck squamous cell carcinoma
- (2016) SILKE WEMMERT et al. Oncology Letters
- Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas
- (2016) Florian Bochen et al. Oncotarget
- Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum
- (2015) Stefan Schorr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting thapsigargin towards tumors
- (2015) Nhu Thi Quynh Doan et al. STEROIDS
- Structure of the native Sec61 protein-conducting channel
- (2015) Stefan Pfeffer et al. Nature Communications
- Calcium Efflux From the Endoplasmic Reticulum Leads to β-Cell Death
- (2014) Takashi Hara et al. ENDOCRINOLOGY
- Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells
- (2013) Maximilian Linxweiler et al. BMC CANCER
- Hepatocellular carcinoma as extracolonic manifestation of Lynch syndrome indicatesSEC63as potential target gene in hepatocarcinogenesis
- (2013) Markus Casper et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Systematic Interrogation of 3q26 Identifies TLOC1 and SKIL as Cancer Drivers
- (2013) D. Hagerstrand et al. Cancer Discovery
- Trifluoperazine, an Antipsychotic Agent, Inhibits Cancer Stem Cell Growth and Overcomes Drug Resistance of Lung Cancer
- (2012) Chi-Tai Yeh et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- CK2 phosphorylation of human Sec63 regulates its interaction with Sec62
- (2012) Emmanuel Ampofo et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER
- (2012) Nico Schäuble et al. EMBO JOURNAL
- Different effects of Sec61 , Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells
- (2012) S. Lang et al. JOURNAL OF CELL SCIENCE
- Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response
- (2012) Jaya Sangodkar et al. JOURNAL OF CLINICAL INVESTIGATION
- Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation
- (2012) Asvin K. K. Lakkaraju et al. MOLECULAR BIOLOGY OF THE CELL
- Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection
- (2012) Li Weng et al. Molecular Cancer
- Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy
- (2012) S. R. Denmeade et al. Science Translational Medicine
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Sec62 Bridges the Gap from 3q Amplification to Molecular Cell Biology in Non–Small Cell Lung Cancer
- (2011) Maximilian Linxweiler et al. AMERICAN JOURNAL OF PATHOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Sec61 complexes form ubiquitous ER Ca2+leak channels
- (2011) Sven Lang et al. Channels
- Identification of SEC61β and its autoantibody as biomarkers for colorectal cancer
- (2011) Chung-Wei Fan et al. CLINICA CHIMICA ACTA
- An interaction between human Sec63 and nucleoredoxin may provide the missing link between theSEC63gene and polycystic liver disease
- (2011) Linda Müller et al. FEBS LETTERS
- Sec62 protein level is crucial for the ER stress tolerance of prostate cancer
- (2011) Markus Greiner et al. PROSTATE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Interaction of calmodulin with Sec61α limits Ca2+leakage from the endoplasmic reticulum
- (2010) Frank Erdmann et al. EMBO JOURNAL
- Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry
- (2010) Jinn-Shiun Chen et al. FEBS Journal
- Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells
- (2010) Markus Greiner et al. INTERNATIONAL JOURNAL OF CANCER
- Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans
- (2010) Linda Müller et al. MOLECULAR BIOLOGY OF THE CELL
- Glioblastoma Proto-oncogene SEC61 Is Required for Tumor Cell Survival and Response to Endoplasmic Reticulum Stress
- (2009) Z. Lu et al. CANCER RESEARCH
- Functions and pathologies of BiP and its interaction partners
- (2009) J. Dudek et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Genome-wide analysis of DNA copy number alterations and gene expression in gastric cancer
- (2008) Y Tsukamoto et al. JOURNAL OF PATHOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started