Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum

Protein Transport into the Human Endoplasmic Reticulum

(2015) Johanna Dudek et al.   JOURNAL OF MOLECULAR BIOLOGY

Absence of BiP Co-chaperone DNAJC3 Causes Diabetes Mellitus and Multisystemic Neurodegeneration

(2014) Matthis Synofzik et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Myopathy in Marinesco–Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology

(2013) Andreas Roos et al.   ACTA NEUROPATHOLOGICA

Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells

(2013) Maximilian Linxweiler et al.   BMC CANCER

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation

(2013) Jeffrey M. Williams et al.   MOLECULAR BIOLOGY OF THE CELL

Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects

(2013) Jill M. Fritz et al.   MOLECULAR BIOLOGY OF THE CELL

BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER

(2012) Nico Schäuble et al.   EMBO JOURNAL

Different effects of Sec61 , Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells

(2012) S. Lang et al.   JOURNAL OF CELL SCIENCE

TRC40 can deliver short secretory proteins to the Sec61 translocon

(2012) N. Johnson et al.   JOURNAL OF CELL SCIENCE

Sec62 Bridges the Gap from 3q Amplification to Molecular Cell Biology in Non–Small Cell Lung Cancer

(2011) Maximilian Linxweiler et al.   AMERICAN JOURNAL OF PATHOLOGY

Sec61 complexes form ubiquitous ER Ca2+leak channels

(2011) Sven Lang et al.   Channels

Receptor for Activated C Kinase 1 (RACK1) Inhibits Function of Transient Receptor Potential (TRP)-type Channel Pkd2L1 through Physical Interaction

(2011) Jungwoo Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation

(2011) Sorin V Fedeles et al.   NATURE GENETICS

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

(2011) Moritz Marcinowski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Overexpression of GRP78 protects glial cells from endoplasmic reticulum stress

(2011) Kaori Suyama et al.   NEUROSCIENCE LETTERS

Protein translocation across the ER membrane

(2010) Richard Zimmermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Signaling cell death from the endoplasmic reticulum stress response

(2010) Gordon C Shore et al.   CURRENT OPINION IN CELL BIOLOGY

Interaction of calmodulin with Sec61α limits Ca2+leakage from the endoplasmic reticulum

(2010) Frank Erdmann et al.   EMBO JOURNAL

Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells

(2010) Markus Greiner et al.   INTERNATIONAL JOURNAL OF CANCER

Organization of the Sec61 Translocon, Studied by High Resolution Native Electrophoresis

(2010) Kurt Dejgaard et al.   JOURNAL OF PROTEOME RESEARCH

A Point Mutation in Sec61 1 Leads to Diabetes and Hepatosteatosis in Mice

(2009) D. J. Lloyd et al.   DIABETES

TRPC5 Is a Ca2+-activated Channel Functionally Coupled to Ca2+-selective Ion Channels

(2009) Stefan Alfred Gross et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7

(2009) René P. Zahedi et al.   PROTEOMICS

Life and death of a BiP substrate

(2009) Joel H. Otero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3

(2008) Kseniya Petrova et al.   EMBO JOURNAL

Conformational transition of Sec machinery inferred from bacterial SecYE structures

(2008) Tomoya Tsukazaki et al.   NATURE

BiP mutants that are unable to interact with endoplasmic reticulum DnaJ proteins provide insights into interdomain interactions in BiP

(2008) W. Awad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA