An interaction between human Sec63 and nucleoredoxin may provide the missing link between theSEC63gene and polycystic liver disease

Molecular Advances in Autosomal Dominant Polycystic Kidney Disease

(2010) Anna Rachel Gallagher et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Secondary and tertiary structure modeling reveals effects of novel mutations in polycystic liver disease genes PRKCSH and SEC63

(2010) E Waanders et al.   CLINICAL GENETICS

Nucleoredoxin Sustains Wnt/β-Catenin Signaling by Retaining a Pool of Inactive Dishevelled Protein

(2010) Yosuke Funato et al.   CURRENT BIOLOGY

Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans

(2010) Linda Müller et al.   MOLECULAR BIOLOGY OF THE CELL

TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum

(2009) Tomasz Wegierski et al.   EMBO JOURNAL

Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase

(2009) Vladimir Pena et al.   MOLECULAR CELL

Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2

(2009) Lingdi Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cysts of PRKCSH mutated polycystic liver disease patients lack hepatocystin but express Sec63p

(2008) Esmé Waanders et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Polycystin-2 is regulated by endoplasmic reticulum-associated degradation

(2008) G. Liang et al.   HUMAN MOLECULAR GENETICS

Disrupted cell adhesion but not proliferation mediates cyst formation in polycystic liver disease

(2008) Esmé Waanders et al.   MODERN PATHOLOGY