Gut microbiome and microbial metabolites in NAFLD and after bariatric surgery: Correlation and causality

Microbiome-based therapeutics

(2022) Matthew T. Sorbara et al.   NATURE REVIEWS MICROBIOLOGY

Laparoscopic sleeve gastrectomy for morbid obesity improves gut microbiota balance, increases colonic mucosal-associated invariant T cells and decreases circulating regulatory T cells

(2022) Naoki Fukuda et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Compensatory intestinal antibody response against pro-inflammatory microbiota after bariatric surgery

(2022) Torsten P.M. Scheithauer et al.   Gut Microbes

Integrated metagenomics and metabolomics analysis illustrates the systemic impact of the gut microbiota on host metabolism after bariatric surgery

(2022) Yeyoung Han et al.   DIABETES OBESITY & METABOLISM

Roux-en-Y gastric bypass and sleeve gastrectomy induce substantial and persistent changes in microbial communities and metabolic pathways

(2022) Jerry T. Dang et al.   Gut Microbes

Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity

(2022) Julia Münzker et al.   Microbiome

A microbial metabolite remodels the gut-liver axis following bariatric surgery

(2021) Snehal N. Chaudhari et al.   Cell Host & Microbe

Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma

(2021) Jason Behary et al.   Nature Communications

Gastric Bypass Increases Circulating Bile Acids and Activates Hepatic Farnesoid X Receptor (FXR) but Requires Intact Peroxisome Proliferator Activator Receptor Alpha (PPARα) Signaling to Significantly Reduce Liver Fat Content

(2021) Guilherme S. Mazzini et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Mechanisms and disease consequences of nonalcoholic fatty liver disease

(2021) Rohit Loomba et al.   CELL

Association of metabolic–bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants

(2021) Nicholas L Syn et al.   LANCET

Gastric Bypass Compared with Sleeve Gastrectomy for Nonalcoholic Fatty Liver Disease: a Systematic Review and Meta-analysis

(2021) Miller Barreto de Brito e Silva et al.   OBESITY SURGERY

Factors Related to Weight Loss Maintenance in the Medium–Long Term after Bariatric Surgery: A Review

(2021) Isabel Cornejo-Pareja et al.   Journal of Clinical Medicine

Chains of evidence from correlations to causal molecules in microbiome-linked diseases

(2021) Snehal N. Chaudhari et al.   Nature Chemical Biology

Bariatric Surgery and Liver Disease: General Considerations and Role of the Gut–Liver Axis

(2021) Maria Cerreto et al.   Nutrients

Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype

(2021) Jia V. Li et al.   Microbiome

Projection of Gut Microbiome Pre- and Post-Bariatric Surgery To Predict Surgery Outcome

(2021) Meirav Ben Izhak et al.   mSystems

Gut Microbiome and Metabolites in Patients with NAFLD and after Bariatric Surgery: A Comprehensive Review

(2021) Jacqueline Hoozemans et al.   Metabolites

Role of ANGPTL8 in NAFLD Improvement after Bariatric Surgery in Experimental and Human Obesity

(2021) Carolina M. Perdomo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The fecal mycobiome in non-alcoholic fatty liver disease

(2021) Münevver Demir et al.   JOURNAL OF HEPATOLOGY

Gut Microbiota Metabolism of Bile Acids Could Contribute to the Bariatric Surgery Improvements in Extreme Obesity

(2021) Luis Ocaña-Wilhelmi et al.   Metabolites

L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling

(2020) Mari Lilith Lund et al.   DIABETES

Diet change affects intestinal microbiota restoration and improves vertical sleeve gastrectomy outcome in diet-induced obese rats

(2020) Joana Rossell et al.   EUROPEAN JOURNAL OF NUTRITION

NAFLD 2020: The State of the Disease

(2020) Thomas G. Cotter et al.   GASTROENTEROLOGY

Endotoxin Producers Overgrowing in Human Gut Microbiota as the Causative Agents for Nonalcoholic Fatty Liver Disease

(2020) Na Fei et al.   mBio

Adipokines and Endotoxemia Correlate with Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease (NAFLD)

(2020) Anika Nier et al.   Nutrients

Lactobacillus and Pediococcus ameliorate progression of non-alcoholic fatty liver disease through modulation of the gut microbiome

(2020) Na Young Lee et al.   Gut Microbes

Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability

(2020) Laura Craven et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Bariatric Surgery is Associated With Decreased Progression of Nonalcoholic Fatty Liver Disease to Cirrhosis

(2020) Keith M. Wirth et al.   ANNALS OF SURGERY

Endogenous ethanol produced by intestinal bacteria induces mitochondrial dysfunction in nonalcoholic fatty liver disease

(2020) Xiao Chen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Bile acids associate with specific gut microbiota, low‐level alcohol consumption and liver fibrosis in patients with non‐alcoholic fatty liver disease

(2020) Leon A. Adams et al.   LIVER INTERNATIONAL

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

(2020) Judith Aron-Wisnewsky et al.   Nature Reviews Gastroenterology & Hepatology

Is bariatric surgery resolving NAFLD via microbiota-mediated bile acid ratio reversal? A comprehensive review

(2020) Eider Talavera-Urquijo et al.   Surgery for Obesity and Related Diseases

Impact of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy on gut microbiota: a metagenomic comparative analysis

(2020) William Farin et al.   Surgery for Obesity and Related Diseases

Gut microbiota differs a decade after bariatric surgery relative to a nonsurgical comparison group

(2020) Jacob G. Mabey et al.   Surgery for Obesity and Related Diseases

Temporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery

(2020) Zehra Esra Ilhan et al.   npj Biofilms and Microbiomes

Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis

(2020) Guillaume Lassailly et al.   GASTROENTEROLOGY

Roux-en-Y gastric bypass surgery changes fungal and bacterial microbiota in morbidly obese patients—A pilot study

(2020) Robert E. Steinert et al.   PLoS One

Duodenal-jejunal bypass improves nonalcoholic fatty liver disease independently of weight loss in rodents with diet-induced obesity

(2020) Giulia Angelini et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal permeability in human nonalcoholic fatty liver disease: A systematic review and meta‐analysis

(2020) Toon J. I. De Munck et al.   LIVER INTERNATIONAL

Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

(2020) Giljae Lee et al.   Nature Communications

AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review

(2020) Zobair M. Younossi et al.   GASTROENTEROLOGY

A body weight loss- and health-promoting gut microbiota is established after bariatric surgery in individuals with severe obesity

(2020) Sergio Sanchez-Carrillo et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

(2020) Daniel Q. Huang et al.   Nature Reviews Gastroenterology & Hepatology

The role of the gut microbiome and its metabolites in metabolic diseases

(2020) Jiayu Wu et al.   Protein & Cell

Weight Loss After Bariatric Surgery Predicts an Improvement in the Non-alcoholic Fatty Liver Disease (NAFLD) Fibrosis Score

(2019) Shanwen Charleen Yeo et al.   OBESITY SURGERY

The Role of the Gut Microbiota in Sustained Weight Loss Following Roux-en-Y Gastric Bypass Surgery

(2019) Farnaz Fouladi et al.   OBESITY SURGERY

Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

(2019) Lulu Sun et al.   Acta Pharmaceutica Sinica B

A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease

(2019) Cyrielle Caussy et al.   Nature Communications

Altered gut microbiome after bariatric surgery and its association with metabolic benefits: A systematic review

(2019) Naomi K. Davies et al.   Surgery for Obesity and Related Diseases

Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects

(2019) Yeojun Yun et al.   PLoS One

Metabolic improvement in obese patients after duodenal–jejunal exclusion is associated with intestinal microbiota composition changes

(2019) C. de Jonge et al.   INTERNATIONAL JOURNAL OF OBESITY

Trimethylamine N ‐Oxide Aggravates Liver Steatosis through Modulation of Bile Acid Metabolism and Inhibition of Farnesoid X Receptor Signaling in Nonalcoholic Fatty Liver Disease

(2019) Xuying Tan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Changes in Gut Microbiome after Bariatric Surgery Versus Medical Weight Loss in a Pilot Randomized Trial

(2019) Clare J. Lee et al.   OBESITY SURGERY

Longitudinal changes of microbiome composition and microbial metabolomics after surgical weight loss in individuals with obesity

(2019) Nan Shen et al.   Surgery for Obesity and Related Diseases

Gut Microbiota and Risk of Persistent Nonalcoholic Fatty Liver Diseases

(2019) Han-Na Kim et al.   Journal of Clinical Medicine

Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation

(2019) Dong Hun Lee et al.   Cell Communication and Signaling

Lean NAFLD : A Distinct Entity Shaped by Differential Metabolic Adaptation

(2019) Fei Chen et al.   HEPATOLOGY

Circulating microbiota-derived metabolites: a “liquid biopsy?

(2019) Gemma Aragonès et al.   INTERNATIONAL JOURNAL OF OBESITY

Gut microbiota adaptation after weight loss by Roux-en-Y gastric bypass or sleeve gastrectomy bariatric surgeries

(2019) Lidia Sánchez-Alcoholado et al.   Surgery for Obesity and Related Diseases

The gut-liver axis in liver disease: pathophysiological basis for therapy

(2019) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Differential Effects of Typical Korean Versus American-Style Diets on Gut Microbial Composition and Metabolic Profile in Healthy Overweight Koreans: A Randomized Crossover Trial

(2019) Ji-Hee Shin et al.   Nutrients

Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

(2019) Mattea Müller et al.   Scientific Reports

New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery

(2019) Giulia Angelini et al.   Scientific Reports

Increased liver localization of lipopolysaccharides in human and experimental non‐alcoholic fatty liver disease

(2019) Guido Carpino et al.   HEPATOLOGY

Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy

(2018) Cyrus Jahansouz et al.   ANNALS OF SURGERY

Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018

(2018) Joseph JY Sung et al.   GUT

Dietary fiber increases the butyrate-producing bacteria and improves growth performance of weaned piglets

(2018) Jinbiao Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016–2030

(2018) Chris Estes et al.   JOURNAL OF HEPATOLOGY

Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: A prospective pilot study

(2018) S.M.B. Duarte et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

(2018) Christoph A. Thaiss et al.   SCIENCE

Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-Analysis

(2018) Yung Lee et al.   Clinical Gastroenterology and Hepatology

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

Pioglitazone Reduces Hepatocellular Carcinoma Development in Two Rodent Models of Cirrhosis

(2018) Shen Li et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome

(2018) Luigi Barrea et al.   Nutrients

The Role of GLP-1 in the Metabolic Success of Bariatric Surgery

(2017) Chelsea R Hutch et al.   ENDOCRINOLOGY

Modulation of the gut microbiome: a systematic review of the effect of bariatric surgery

(2017) Yan Guo et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

(2017) Na Jiao et al.   GUT

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids

(2017) Puneet Puri et al.   HEPATOLOGY

Distinctive microbiomes and metabolites linked with weight loss after gastric bypass, but not gastric banding

(2017) Zehra Esra Ilhan et al.   ISME Journal

Treatment of NAFLD with diet, physical activity and exercise

(2017) Manuel Romero-Gómez et al.   JOURNAL OF HEPATOLOGY

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

Hepatic farnesoid X receptor protein level and circulating fibroblast growth factor 19 concentration in children with NAFLD

(2017) Valerio Nobili et al.   LIVER INTERNATIONAL

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

(2017) Ruixin Liu et al.   NATURE MEDICINE

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Microbiota-derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo

(2017) M. Jennis et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Bariatric Surgery as an Efficient Treatment for Non-Alcoholic Fatty Liver Disease in a Prospective Study with 1-Year Follow-up

(2017) Felix Nickel et al.   OBESITY SURGERY

Bile acid profiles over 5 years after gastric bypass and duodenal switch: results from a randomized clinical trial

(2017) Hilde Risstad et al.   Surgery for Obesity and Related Diseases

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

(2017) Da Zhou et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease: is universal screening appropriate?

(2016) Christopher D. Byrne et al.   DIABETOLOGIA

The Gut Bacteria-Driven Obesity Development

(2016) Debora Compare et al.   DIGESTIVE DISEASES

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

The Gut Microbiota

(2016) Kristina B. Martinez et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Microbiota-induced obesity requires farnesoid X receptor

(2016) Ava Parséus et al.   GUT

The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach

(2016) Federica Del Chierico et al.   HEPATOLOGY

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

Gut microbiota-associated bile acid deconjugation accelerates hepatic steatosis in ob/ob mice

(2016) M.-Y. Park et al.   JOURNAL OF APPLIED MICROBIOLOGY

Systematic transcriptome analysis reveals elevated expression of alcohol-metabolizing genes in NAFLD livers

(2016) Ruixin Zhu et al.   JOURNAL OF PATHOLOGY

Trimethylamine-N-oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A randomized controlled trial

(2016) Clara E. Cho et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

Bariatric surgery for obesity and metabolic disorders: state of the art

(2016) Ninh T. Nguyen et al.   Nature Reviews Gastroenterology & Hepatology

Differential Changes in Gut Microbiota After Gastric Bypass and Sleeve Gastrectomy Bariatric Surgery Vary According to Diabetes Remission

(2016) Rinki Murphy et al.   OBESITY SURGERY

Nuclear Receptor Modulation for the Treatment of Nonalcoholic Fatty Liver Disease

(2016) Claudia Fuchs et al.   SEMINARS IN LIVER DISEASE

Gut microbiota and metabolic syndrome

(2016) Davide Festi et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults

(2016) Yu-ming Chen et al.   Scientific Reports

A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet

(2016) Gabsik Yang et al.   Scientific Reports

Altered Fecal Microbiota Correlates with Liver Biochemistry in Nonobese Patients with Non-alcoholic Fatty Liver Disease

(2016) Baohong Wang et al.   Scientific Reports

Microbiology Meets Big Data: The Case of Gut Microbiota–Derived Trimethylamine

(2015) Gwen Falony et al.   Annual Review of Microbiology

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

(2015) Valentina Tremaroli et al.   Cell Metabolism

FXR Agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease

(2015) Rotonya M. Carr et al.   Current Atherosclerosis Reports

Bariatric Surgery Reduces Features of Nonalcoholic Steatohepatitis in Morbidly Obese Patients

(2015) Guillaume Lassailly et al.   GASTROENTEROLOGY

Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

(2015) Anna Janina Engstler et al.   GUT

Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes

(2015) R Dutia et al.   INTERNATIONAL JOURNAL OF OBESITY

Changes in Bile Acid Profile After Laparoscopic Sleeve Gastrectomy are Associated with Improvements in Metabolic Profile and Fatty Liver Disease

(2015) Ajay P. Belgaumkar et al.   OBESITY SURGERY

Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria

(2015) Ana Martínez-del Campo et al.   mBio

Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease

(2015) Weiwei Jiang et al.   Scientific Reports

Activation of farnesoid X receptor (FXR) protects against fructose-induced liver steatosis via inflammatory inhibition and ADRP reduction

(2014) Xijun Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease

(2014) Kouichi Miura   WORLD JOURNAL OF GASTROENTEROLOGY

Fecal Microbiome and Volatile Organic Compound Metabolome in Obese Humans With Nonalcoholic Fatty Liver Disease

(2013) Maitreyi Raman et al.   Clinical Gastroenterology and Hepatology

Bile acids and gut peptide secretion after bariatric surgery: A 1-year prospective randomized pilot trial

(2013) Robert E. Steinert et al.   Obesity

Differential Effects of Laparoscopic Sleeve Gastrectomy and Laparoscopic Gastric Bypass on Appetite, Circulating Acyl-ghrelin, Peptide YY3-36 and Active GLP-1 Levels in Non-diabetic Humans

(2013) Ahmed Yousseif et al.   OBESITY SURGERY

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity

(2013) A. P. Liou et al.   Science Translational Medicine

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content

(2012) Mohamed Bellahcene et al.   BRITISH JOURNAL OF NUTRITION

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

GLP-1 Response to a Mixed Meal: What Happens 10 Years after Roux-en-Y Gastric Bypass (RYGB)?

(2012) Moahad S. Dar et al.   OBESITY SURGERY

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

Nonalcoholic fatty liver disease

(2011) Marcin Krawczyk et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

(2011) Matthew J. Potthoff et al.   Cell Metabolism

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

(2011) Karen D. Corbin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Alterations of Hormonally Active Fibroblast Growth Factors after Roux-en-Y Gastric Bypass Surgery

(2011) Peter L.M. Jansen et al.   DIGESTIVE DISEASES

Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine- and choline-deficient diet

(2011) Vyacheslav U. Buko et al.   HEPATOLOGY RESEARCH

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure

(2011) Mitsuhiro Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis

(2011) Gianluca Svegliati-Baroni et al.   LIVER INTERNATIONAL

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance after Roux-en-Y gastric bypass surgery in patients with morbid obesity and type 2 diabetes mellitus

(2011) Scott V. Monte et al.   SURGERY

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Role of Alcohol Metabolism in Non-Alcoholic Steatohepatitis

(2010) Susan S. Baker et al.   PLoS One

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Kupffer cells promote hepatic steatosis via interleukin-1β-dependent suppression of peroxisome proliferator-activated receptor α activity

(2009) Rinke Stienstra et al.   HEPATOLOGY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Surgical treatment of obesity

(2008) Mariëlle J F Bult et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA