Smp24, a Scorpion-Venom Peptide, Exhibits Potent Antitumor Effects against Hepatoma HepG2 Cells via Multi-Mechanisms In Vivo and In Vitro

Scorpion Venom Antimicrobial Peptides Induce Caspase-1 Dependant Pyroptotic Cell Death

(2022) Ranwa A. Elrayess et al.   Frontiers in Pharmacology

Scorpion Peptide Smp24 Exhibits a Potent Antitumor Effect on Human Lung Cancer Cells by Damaging the Membrane and Cytoskeleton In Vivo and In Vitro

(2022) Ruiyin Guo et al.   Toxins

The Strong Anti-Tumor Effect of Smp24 in Lung Adenocarcinoma A549 Cells Depends on Its Induction of Mitochondrial Dysfunctions and ROS Accumulation

(2022) Ruiyin Guo et al.   Toxins

LvHemB1, a novel cationic antimicrobial peptide derived from the hemocyanin of Litopenaeus vannamei, induces cancer cell death by targeting mitochondrial voltage-dependent anion channel 1

(2021) Shangjie Liu et al.   CELL BIOLOGY AND TOXICOLOGY

Autophagy-related signaling pathways are involved in cancer (Review)

(2021) Caixia Chen et al.   Experimental and Therapeutic Medicine

Ginkgolic acid induces apoptosis and autophagy of endometrial carcinoma cells via inhibiting PI3K/Akt/mTOR pathway in vivo and in vitro

(2021) L Zhou et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Antitumor Effects of Scorpion Peptide Smp43 through Mitochondrial Dysfunction and Membrane Disruption on Hepatocellular Carcinoma

(2021) Jinwei Chai et al.   JOURNAL OF NATURAL PRODUCTS

Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress

(2021) Xiaohe Hao et al.   ONCOGENE

Novel Peptide Therapeutic Approaches for Cancer Treatment

(2021) Caroline M. Li et al.   Cells

Regulation of Mitochondrial Function by the Actin Cytoskeleton

(2021) María Illescas et al.   Frontiers in Cell and Developmental Biology

Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities

(2020) Anna Lucia Tornesello et al.   MOLECULES

Quercetin inhibits growth of hepatocellular carcinoma by apoptosis induction in part via autophagy stimulation in mice

(2019) Yi Ji et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

PI3K/Akt/mTOR inhibitors in cancer: At the bench and bedside

(2019) Ali S. Alzahrani   SEMINARS IN CANCER BIOLOGY

Antimicrobial peptides as novel therapeutics for non-small cell lung cancer

(2019) Nitesh K. Kunda   DRUG DISCOVERY TODAY

Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways

(2019) Dhanasekhar Reddy et al.   Biomolecules

Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients

(2019) Jean M. Mulcahy Levy et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

(2018) Jiali Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide

(2018) Bin Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MSP-4, an Antimicrobial Peptide, Induces Apoptosis via Activation of Extrinsic Fas/FasL- and Intrinsic Mitochondria-Mediated Pathways in One Osteosarcoma Cell Line

(2018) Hsiao-Mei Kuo et al.   Marine Drugs

N-myristoylation of Antimicrobial Peptide CM4 Enhances Its Anticancer Activity by Interacting With Cell Membrane and Targeting Mitochondria in Breast Cancer Cells

(2018) Caiyun Li et al.   Frontiers in Pharmacology

Treating autoimmune disorders with venom-derived peptides

(2017) Bingzheng Shen et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus

(2016) Patrick L. Harrison et al.   TOXICON

Isolation of a novel bio-peptide from walnut residual protein inducing apoptosis and autophagy on cancer cells

(2015) Sihui Ma et al.   BMC Complementary and Alternative Medicine

Zyxin Antagonizes the FERM Protein Expanded to Couple F-Actin and Yorkie-Dependent Organ Growth

(2015) Pedro Gaspar et al.   CURRENT BIOLOGY

Melanoma cell surface-expressed phosphatidylserine as a therapeutic target for cationic anticancer peptide, temporin-1CEa

(2015) Che Wang et al.   JOURNAL OF DRUG TARGETING

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines

(2015) Michael I. Koukourakis et al.   PLoS One

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

The Membrane-Lytic Peptides K8L9 and Melittin Enter Cancer Cells via Receptor Endocytosis following Subcytotoxic Exposure

(2014) Masayuki Kohno et al.   CHEMISTRY & BIOLOGY

Mitochondria-mediated apoptosis in mammals

(2014) Shunbin Xiong et al.   Protein & Cell

Scorpion venom peptides with no disulfide bridges: A review

(2013) Ammar Almaaytah et al.   PEPTIDES

FK-16 Derived from the Anticancer Peptide LL-37 Induces Caspase-Independent Apoptosis and Autophagic Cell Death in Colon Cancer Cells

(2013) Shun X. Ren et al.   PLoS One

From antimicrobial to anticancer peptides. A review

(2013) Diana Gaspar et al.   Frontiers in Microbiology

Role of the Crosstalk between Autophagy and Apoptosis in Cancer

(2013) Minfei Su et al.   Journal of Oncology

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mitochondrial Regulation of Cell Cycle and Proliferation

(2011) Valeria Gabriela Antico Arciuch et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

(2011) P. H. Reddy et al.   Current Alzheimer Research

Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells

(2010) Yang Sun et al.   CANCER LETTERS

The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells

(2009) Bodil Fadnes et al.   BMC CANCER

Cationic amphiphilic peptides with cancer-selective toxicity

(2009) Frank Schweizer   EUROPEAN JOURNAL OF PHARMACOLOGY

Mediation, Modulation, and Consequences of Membrane-Cytoskeleton Interactions

(2008) Gary J. Doherty et al.   Annual Review of Biophysics

Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide

(2008) Hyun Soo Lee et al.   CANCER LETTERS

Studies on anticancer activities of antimicrobial peptides

(2007) David W. Hoskin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES