Investigation of the ionic conditions in SiRNA-mediated delivery through its carriers in the cell membrane: a molecular dynamic simulation

Design and simulation of the liposomal model by using a coarse-grained molecular dynamics approach towards drug delivery goals

(2022) Jalil Parchekani et al.   Scientific Reports

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

(2021) Rita E. Chen et al.   NATURE MEDICINE

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization

(2021) Pengfei Wang et al.   Cell Host & Microbe

Cations Regulate Membrane Attachment and Functionality of DNA Nanostructures

(2021) Diana Morzy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

siRNA Therapeutics for the Therapy of COVID-19 and Other Coronaviruses

(2021) Muhammad Imran Sajid et al.   MOLECULAR PHARMACEUTICS

A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19

(2021) Adi Idris et al.   MOLECULAR THERAPY

A review of the tortuous path of nonviral gene delivery and recent progress

(2021) Divya Sharma et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Microfluidic investigation of the effect of graphene oxide on mechanical properties of cell and actin cytoskeleton networks: experimental and theoretical approaches

(2021) Mohammad Ghorbani et al.   Scientific Reports

siRNA as a potential therapy for COVID-19

(2021) Ahmad Aljaberi et al.   Current Drug Delivery

Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs

(2021) Yuta Suzuki et al.   Drug Metabolism and Pharmacokinetics

Nanoparticle‐mediated double‐stranded RNA delivery system: A promising approach for sustainable pest management

(2020) Shuo Yan et al.   Insect Science

Overcoming Barriers for siRNA Therapeutics: From Bench to Bedside

(2020) Muhammad Imran Sajid et al.   Pharmaceuticals

Magnesium Contact Ions Stabilize the Tertiary Structure of Transfer RNA: Electrostatics Mapped by Two-Dimensional Infrared Spectra and Theoretical Simulations

(2020) Jakob Schauss et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Insight into the Mechanism of Carrier-Mediated Delivery of siRNA in the Cell Membrane Using MD Simulation

(2020) Ipsita Basu et al.   LANGMUIR

Toward Understanding Liposome-Based siRNA Delivery Vectors: Atomic-Scale Insight into siRNA–Lipid Interactions

(2018) Alexandra Yu. Antipina et al.   LANGMUIR

Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

(2018) Ryota Yamagami et al.   Nature Communications

Improving siRNA Delivery In Vivo Through Lipid Conjugation

(2018) Maire F. Osborn et al.   Nucleic Acid Therapeutics

Steered molecular dynamics simulations reveal a self-protecting configuration of nanoparticles during membrane penetration

(2018) Yousef Nademi et al.   Nanoscale

Advances in siRNA delivery in cancer therapy

(2017) Aishwarya Singh et al.   Artificial Cells Nanomedicine and Biotechnology

Overcoming the Challenges of siRNA Delivery: Nanoparticle Strategies

(2017) Neda Shajari et al.   Current Drug Delivery

RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?

(2016) Maggie L. Bobbin et al.   Annual Review of Pharmacology and Toxicology

Self-organization of nucleic acids in lipid constructs

(2016) Minjee Kang et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

From the RNA world to the clinic

(2016) B. A. Sullenger et al.   SCIENCE

Preclinical and clinical development of siRNA-based therapeutics

(2015) Gulnihal Ozcan et al.   ADVANCED DRUG DELIVERY REVIEWS

The General AMBER Force Field (GAFF) Can Accurately Predict Thermodynamic and Transport Properties of Many Ionic Liquids

(2015) K. G. Sprenger et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Liposomal siRNA nanocarriers for cancer therapy

(2014) Bulent Ozpolat et al.   ADVANCED DRUG DELIVERY REVIEWS

CHARMM-GUIMembrane Buildertoward realistic biological membrane simulations

(2014) Emilia L. Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Calcium-mediated binding of DNA to 1,2-distearoyl-sn-glycero-3-phosphocholine-containing mixed lipid monolayers

(2014) Aleksandra P. Dabkowska et al.   Soft Matter

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells

(2013) K. Adamala et al.   SCIENCE

A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy

(2012) Yang Ding et al.   BIOMATERIALS

Transport of siRNA through Lipid Membranes Driven by Nanosecond Electric Pulses: An Experimental and Computational Study

(2012) Marie Breton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human tRNASec associates with HeLa membranes, cell lipid liposomes, and synthetic lipid bilayers

(2012) T. Janas et al.   RNA

Recent Advances in Nonviral Vectors for Gene Delivery

(2011) Xia Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Effect of Polymer Structure on Micelles Formed between siRNA and Cationic Block Copolymer Comprising Thiols and Amidines

(2011) R. James Christie et al.   BIOMACROMOLECULES

Investigation of siRNA-Loaded Polyethylenimine-Coated Human Serum Albumin Nanoparticle Complexes for the Treatment of Breast Cancer

(2011) Sana Abbasi et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Anionic polymers for decreased toxicity and enhanced in vivo delivery of siRNA complexed with cationic liposomes

(2011) Anne Schlegel et al.   JOURNAL OF CONTROLLED RELEASE

Microfluidic approaches for gene delivery and gene therapy

(2011) Jungkyu Kim et al.   LAB ON A CHIP

Phase Separation on a Phospholipid Membrane Inducing a Characteristic Localization of DNA Accompanied by Its Structural Transition

(2010) Ayako Kato et al.   Journal of Physical Chemistry Letters

Elimination Pathways of Systemically Delivered siRNA

(2010) Yuanyu Huang et al.   MOLECULAR THERAPY

siRNA delivery systems for cancer treatment

(2009) Yu-Kyoung Oh et al.   ADVANCED DRUG DELIVERY REVIEWS

Binding of DNA to Zwitterionic Lipid Layers Mediated by Divalent Cations

(2009) Demmelash H. Mengistu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

DNA Binding to Zwitterionic Model Membranes

(2009) Marie-Louise Ainalem et al.   LANGMUIR

Web 3DNA--a web server for the analysis, reconstruction, and visualization of three-dimensional nucleic-acid structures

(2009) G. Zheng et al.   NUCLEIC ACIDS RESEARCH

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS