Journal
LAB ON A CHIP
Volume 11, Issue 23, Pages 3941-3948Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1lc20766k
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Funding
- Department of Bioengineering at the University of Washington
- Perkins Coie Award for Discovery
- Canada Research Chairs program
- National Research Foundation of Korea [M10536090001-05N3609-00110, 2011-0021117]
- Ministry of Education, Science and Technology
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Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and optimization of multiple processes and techniques used in gene transfection and the production of gene and drug transporters. Traditional non-viral gene transfection methods, such as electroporation, microinjection and optical gene transfection, are improved from the use of innovative microfluidic systems. Additionally, microfluidic systems have also made the production of many viral and non-viral vectors controlled, automated, and reproducible. In summary, the development and application of microfluidic systems are producing increased efficiency in gene delivery and promise improved gene therapy results.
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