Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus
Authors
Keywords
-
Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-07
DOI
10.1038/s41467-021-23361-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Endothelial dysfunction and arterial stiffness in patients with systemic lupus erythematosus: A systematic review and meta-analysis
- (2020) Claudia Mendoza-Pinto et al. ATHEROSCLEROSIS
- A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus
- (2020) Sonja Hartmann et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Safety and Tolerability of Omalizumab, A Randomized Clinical Trial of Humanized anti-IgE Monoclonal Antibody in Systemic Lupus Erythematosus (STOP LUPUS )
- (2019) Sarfaraz Hasni et al. Arthritis & Rheumatology
- Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus
- (2019) Richard Furie et al. JOURNAL OF CLINICAL INVESTIGATION
- Successful treatment of arthritis and rash with tofacitinib in systemic lupus erythematosus: the experience from a single centre
- (2019) Hanxiao You et al. ANNALS OF THE RHEUMATIC DISEASES
- Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
- (2019) Lina Odqvist et al. ANNALS OF THE RHEUMATIC DISEASES
- Tofacitinib inhibits ox-LDL-induced adhesion of THP-1 monocytes to endothelial cells
- (2019) Xiaoyang Yang et al. Artificial Cells Nanomedicine and Biotechnology
- Pathogenic and Therapeutic Relevance of JAK/STAT Signaling in Systemic Lupus Erythematosus: Integration of Distinct Inflammatory Pathways and the Prospect of Their Inhibition with an Oral Agent
- (2019) Alessia Alunno et al. Cells
- High throughput pSTAT signaling profiling by fluorescent cell barcoding and computational analysis
- (2019) Wanxia Li Tsai et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Deadliest catch
- (2019) Rishi R. Goel et al. CURRENT OPINION IN RHEUMATOLOGY
- Trial of Anifrolumab in Active Systemic Lupus Erythematosus
- (2019) Eric F. Morand et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cardiovascular disease in systemic lupus erythematosus
- (2018) Yudong Liu et al. CURRENT OPINION IN RHEUMATOLOGY
- Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 2 trial
- (2018) Daniel J Wallace et al. LANCET
- Cardiovascular disease in systemic lupus erythematosus: A comprehensive update
- (2017) Mayra Giannelou et al. JOURNAL OF AUTOIMMUNITY
- Reference values of cardio-ankle vascular index in a random sample of a white population
- (2017) Peter Wohlfahrt et al. JOURNAL OF HYPERTENSION
- STAT4 Regulates the CD8+Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-ResistantLdlr−/−Mice
- (2017) Parésa L. Taghavie-Moghadam et al. JOURNAL OF IMMUNOLOGY
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Endothelial dysfunction in early systemic lupus erythematosus patients and controls without previous cardiovascular events
- (2017) Mara Taraborelli et al. ARTHRITIS CARE & RESEARCH
- Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus
- (2017) Richard Furie et al. Arthritis & Rheumatology
- Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription factor 3 activity
- (2016) Carolyne K Smith et al. ANNALS OF THE RHEUMATIC DISEASES
- Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
- (2016) Christian Lood et al. NATURE MEDICINE
- Arterial stiffness and peripheral arterial disease in patients with systemic lupus erythematosus
- (2016) Konstantinos Tziomalos et al. RHEUMATOLOGY INTERNATIONAL
- Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction
- (2016) Yasuko Furumoto et al. Arthritis & Rheumatology
- A pilot study to determine the optimal timing of the Physician Global Assessment (PGA) in patients with systemic lupus erythematosus
- (2015) Cynthia Aranow IMMUNOLOGIC RESEARCH
- The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis
- (2015) Hui-Hsin Chang et al. Arthritis & Rheumatology
- Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2
- (2014) Carmelo Carmona-Rivera et al. ANNALS OF THE RHEUMATIC DISEASES
- Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis
- (2014) Jason S. Knight et al. CIRCULATION RESEARCH
- Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN- in Lupus Patients In Vivo
- (2014) S. N. Kariuki et al. JOURNAL OF IMMUNOLOGY
- Neutrophil cell surface receptors and their intracellular signal transduction pathways
- (2013) Krisztina Futosi et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
- (2013) Jason S. Knight et al. JOURNAL OF CLINICAL INVESTIGATION
- JAKs and STATs in Immunity, Immunodeficiency, and Cancer
- (2013) John J. O'Shea et al. NEW ENGLAND JOURNAL OF MEDICINE
- Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis
- (2012) Seth G. Thacker et al. ARTHRITIS AND RHEUMATISM
- Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis
- (2012) Nehal N. Mehta et al. ATHEROSCLEROSIS
- Systemic Lupus Erythematosus
- (2011) George C. Tsokos NEW ENGLAND JOURNAL OF MEDICINE
- Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus
- (2011) G. S. Garcia-Romo et al. Science Translational Medicine
- An assessment of disease flare in patients with systemic lupus erythematosus: a comparison of BILAG 2004 and the flare version of SELENA
- (2010) D. A. Isenberg et al. ANNALS OF THE RHEUMATIC DISEASES
- A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs
- (2010) M. F. Denny et al. JOURNAL OF IMMUNOLOGY
- A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus
- (2009) E. Svenungsson et al. ANNALS OF THE RHEUMATIC DISEASES
- Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus
- (2009) Maureen McMahon et al. ARTHRITIS AND RHEUMATISM
- Specificity of the STAT4 Genetic Association for Severe Disease Manifestations of Systemic Lupus Erythematosus
- (2008) Kimberly E. Taylor et al. PLoS Genetics
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now