Astaxanthin Inhibits Matrix Metalloproteinase Expression by Suppressing PI3K/AKT/mTOR Activation in Helicobacter pylori-Infected Gastric Epithelial Cells

Matrix Metalloproteinases in Helicobacter pylori–Associated Gastritis and Gastric Cancer

(2022) Olga Sokolova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta

(2022) Marco Kirchenwitz et al.   Cells

β-Carotene Inhibits Expression of Matrix Metalloproteinase-10 and Invasion in Helicobacter pylori-Infected Gastric Epithelial Cells

(2021) Suji Bae et al.   MOLECULES

Actin-Like Protein 8 Promotes the Progression of Triple-Negative Breast Cancer via Activating PI3K/AKT/mTOR Pathway

(2021) Shaoxia Fan et al.   OncoTargets and Therapy

Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours

(2020) Fei Xu et al.   Cell and Bioscience

Effect of Astaxanthin on Activation of Autophagy and Inhibition of Apoptosis in Helicobacter pylori-Infected Gastric Epithelial Cell Line AGS

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Helicobacter pylori–induced matrix metallopeptidase-10 promotes gastric bacterial colonization and gastritis

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A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential

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PI3K-AKT-mTOR and NFκB Pathways in Ovarian Cancer: Implications for Targeted Therapeutics

(2019) Alia Ghoneum et al.   Cancers

Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways

(2019) Wu et al.   Marine Drugs

The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma

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Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

(2018) Paula Díaz et al.   Frontiers in Microbiology

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

(2018) Nikos Koundouros et al.   Frontiers in Oncology

Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy

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Astaxanthin: A mechanistic review on its biological activities and health benefits

(2018) Sajad Fakhri et al.   PHARMACOLOGICAL RESEARCH

Astaxanthin Inhibits Mitochondrial Dysfunction and Interleukin-8 Expression in Helicobacter pylori-Infected Gastric Epithelial Cells

(2018) Suhn Kim et al.   Nutrients

Targeted disruption of PI3K/Akt/mTOR signaling pathway, via PI3K inhibitors, promotes growth inhibitory effects in oral cancer cells

(2018) Sadhna Aggarwal et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis

(2018) Chen Shen et al.   JOURNAL OF IMMUNOLOGY

Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1α to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells

(2017) Jimena Canales et al.   Frontiers in Cellular and Infection Microbiology

HelicobacterpyloriActivates Matrix Metalloproteinase 10 in Gastric Epithelial Cells via EGFR and ERK-mediated Pathways

(2016) Angela M. Costa et al.   JOURNAL OF INFECTIOUS DISEASES

Helicobacter pyloriinduces Snail expression through ROS-mediated activation of Erk and inactivation of GSK-3β in human gastric cancer cells

(2016) Hoang-Kieu-Chi Ngo et al.   MOLECULAR CARCINOGENESIS

Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathway

(2016) WEI ZHAO et al.   Molecular Medicine Reports

Apocynin inhibits Toll-like receptor-4-mediated activation of NF-κB by suppressing the Akt and mTOR pathways

(2016) Yoon Jeong Nam et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Lipoxin A4Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer

(2016) Liang Zong et al.   Oxidative Medicine and Cellular Longevity

Multiple Mechanisms of Anti-Cancer Effects Exerted by Astaxanthin

(2015) Li Zhang et al.   Marine Drugs

Prognostic Significance of Matrix Metalloproteinase-7 in Gastric Cancer Survival: A Meta-Analysis

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Jak1/Stat3 Is an Upstream Signaling of NF-κB Activation inHelicobacter pylori-Induced IL-8 Production in Gastric Epithelial AGS Cells

(2015) Boram Cha et al.   YONSEI MEDICAL JOURNAL

Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells

(2015) Heather G. Hambright et al.   Oncotarget

The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

Astaxanthin reduces matrix metalloproteinase expression in human chondrocytes

(2014) Wei-Ping Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of the PI3K/Akt/mTOR/p70S6K Pathway is Involved in S100A4-induced Viability and Migration in Colorectal Cancer Cells

(2014) Haiyan Wang et al.   International Journal of Medical Sciences

Helicobacter pylori infection promotes the invasion and metastasis of gastric cancer through increasing the expression of matrix metalloproteinase-1 and matrix metalloproteinase-10

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Helicobacter pylori CagA promotes Snail-mediated epithelial–mesenchymal transition by reducing GSK-3 activity

(2014) Da-Gyum Lee et al.   Nature Communications

Targeted Regulation of PI3K/Akt/mTOR/NF-κB Signaling by Indole Compounds and their Derivatives: Mechanistic Details and Biological Implications for Cancer Therapy

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Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells

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Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

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Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

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Biological role of matrix metalloproteinases: a critical balance

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Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

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Helicobacter pylori: a ROS-inducing bacterial species in the stomach

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Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds

(2010) Wasaporn Chanput et al.   Food & Function

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

(2009) Andrea Köhrmann et al.   BMC CANCER

Elevated Serum Matrix Metalloproteinase-3 and -7 in H. pylori-Related Gastric Cancer Can Be Biomarkers Correlating with a Poor Survival

(2009) Yi-Chun Yeh et al.   DIGESTIVE DISEASES AND SCIENCES

Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9

(2009) Jing-song Chen et al.   HEPATOLOGY RESEARCH

SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IκBα kinase activation

(2008) Gautam Sethi et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of Gastric Carcinogenesis by Helicobacter pylori Virulence Factors

(2008) A. T. Franco et al.   CANCER RESEARCH

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT