Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways

Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell–Cell Adhesion

(2019) Andrea Dalle Vedove et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway

(2018) Tsung-Chang Tsai et al.   Marine Drugs

Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca2+ and activating the FAK/Rho GTPases signaling pathways in vitro

(2018) Yingchi Zhang et al.   Stem Cell Research & Therapy

The Interdependent Activation of Son-of-Sevenless and Ras

(2018) Pradeep Bandaru et al.   Cold Spring Harbor Perspectives in Medicine

ARHGAP42 promotes cell migration and invasion involving PI3K/Akt signaling pathway in nasopharyngeal carcinoma

(2018) Qian Hu et al.   Cancer Medicine

Bornyl cis-4-Hydroxycinnamate Suppresses Cell Metastasis of Melanoma through FAK/PI3K/Akt/mTOR and MAPK Signaling Pathways and Inhibition of the Epithelial-to-Mesenchymal Transition

(2018) Tzu-Yen Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sinulariolide Suppresses Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase through the PI3K/AKT/mTOR Signaling Pathway in Human Bladder Cancer Cells

(2017) Te-Chih Cheng et al.   Marine Drugs

Sinulariolide suppresses LPS-induced phenotypic and functional maturation of dendritic cells

(2017) Ting-Wen Chung et al.   Molecular Medicine Reports

Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-κB signal pathway

(2016) SHAOQIN CHEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Anticancer Effects of Sinulariolide-Conjugated Hyaluronan Nanoparticles on Lung Adenocarcinoma Cells

(2016) Kuan Hsiao et al.   MOLECULES

Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways

(2015) Yu-Jen Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation

(2014) Mayumi Fujita et al.   FEBS LETTERS

Aberrant expression of B7-H3 in gastric adenocarcinoma promotes cancer cell metastasis

(2014) WEI DAI et al.   ONCOLOGY REPORTS

Expression Profiling Using a cDNA Array and Immunohistochemistry for the Extracellular Matrix Genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in Colorectal Carcinoma Progression and Dissemination

(2014) Suzana Angelica Silva Lustosa et al.   TheScientificWorldJOURNAL

Crosstalk between Beta-Catenin and Snail in the Induction of Epithelial to Mesenchymal Transition in Hepatocarcinoma: Role of the ERK1/2 Pathway

(2013) Nathalie Zucchini-Pascal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

E-cadherin-integrin crosstalk in cancer invasion and metastasis

(2013) M. Canel et al.   JOURNAL OF CELL SCIENCE

Proteomic Investigation of the Sinulariolide-Treated Melanoma Cells A375: Effects on the Cell Apoptosis through Mitochondrial-Related Pathway and Activation of Caspase Cascade

(2013) Hsing-Hui Li et al.   Marine Drugs

Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway

(2013) Yi-Jen Chen et al.   MOLECULES

Role of mTOR Signaling in Tumor Cell Motility, Invasion and Metastasis

(2012) Shile Huang et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Induction of Apoptosis by Sinulariolide from Soft Coral through Mitochondrial-Related and p38MAPK Pathways on Human Bladder Carcinoma Cells

(2012) Choo-Aun Neoh et al.   Marine Drugs

Antimetastatic Effects of Norcantharidin on Hepatocellular Carcinoma by Transcriptional Inhibition of MMP-9 through Modulation of NF-kB Activity

(2012) Chao-Bin Yeh et al.   PLoS One

Monoamine oxidase A variants are associated with heavy betel quid use

(2011) Ping-Ho Chen et al.   ADDICTION BIOLOGY

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression

(2011) Brigitte Bauvois   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Inhibition of MT1-MMP activity using functional antibody fragments selected against its hemopexin domain

(2011) B. Basu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

(2011) D B Badgwell et al.   ONCOGENE

Proteolytic networks in cancer

(2011) Steven D. Mason et al.   TRENDS IN CELL BIOLOGY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Modulators of the urokinase-type plasminogen activation system for cancer

(2010) Ralf Hildenbrand et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

(2010) Chrisostomi Gialeli et al.   FEBS Journal

Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases

(2010) Shun-Fa Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

p38delta/MAPK13 as a diagnostic marker for cholangiocarcinoma and its involvement in cell motility and invasion

(2009) Felicia Li-Sher Tan et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways

(2008) T. T. Onder et al.   CANCER RESEARCH

Grb2 signaling in cell motility and cancer

(2008) Alessio Giubellino et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Validation of staging systems for gastric cancer

(2008) Keishi Yamashita et al.   Gastric Cancer

S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial

(2008) Wasaburo Koizumi et al.   LANCET ONCOLOGY