Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants
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Title
Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants
Authors
Keywords
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Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-09-16
DOI
10.1038/s41467-022-33122-1
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Note: Only part of the references are listed.- Multienzyme One‐Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids
- (2021) Fabiana Subrizi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Copper–Oxygen Dynamics in the Tyrosinase Mechanism
- (2020) Nobutaka Fujieda et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
- (2020) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Design and use of de novo cascades for new benzylisoquinoline alkaloid biosynthesis
- (2019) Helen Claire Hailes et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Acceptance and Kinetic Resolution of α-Methyl-Substituted Aldehydes by Norcoclaurine Synthases
- (2019) Rebecca Roddan et al. ACS Catalysis
- Biocatalytic versatility of engineered and wild-type tyrosinase from R. solanacearum for the synthesis of 4-halocatechols
- (2018) Reeta Davis et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues
- (2018) Jianxiong Zhao et al. CHEMICAL COMMUNICATIONS
- SWISS-MODEL: homology modelling of protein structures and complexes
- (2018) Andrew Waterhouse et al. NUCLEIC ACIDS RESEARCH
- Structural dynamics of the transaminase active site revealed by the crystal structure of a co-factor free omega-transaminase from Vibrio fluvialis JS17
- (2018) Young-Cheul Shin et al. Scientific Reports
- Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways
- (2017) Han-bin Chen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Functional and structural characterisation of a bacterialO-methyltransferase and factors determining regioselectivity
- (2017) Jutta Siegrist et al. FEBS LETTERS
- Isotope effects in mechanistic studies of l-tyrosine halogen derivatives hydroxylation catalyzed by tyrosinase
- (2017) Małgorzata Pająk et al. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
- Family portraits: the enzymes behind benzylisoquinoline alkaloid diversity
- (2017) Mehran Dastmalchi et al. PHYTOCHEMISTRY REVIEWS
- Berberine inhibits the proliferation and migration of breast cancer ZR-75-30 cells by targeting Ephrin-B2
- (2017) Weina Ma et al. PHYTOMEDICINE
- Enzyme catalysed Pictet-Spengler formation of chiral 1,1’-disubstituted- and spiro-tetrahydroisoquinolines
- (2017) Benjamin R. Lichman et al. Nature Communications
- Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
- (2016) Akira Nakagawa et al. Nature Communications
- Multidomain Assembler (MDA) Generates Models of Large Multidomain Proteins
- (2015) Samuel Hertig et al. BIOPHYSICAL JOURNAL
- Regiocomplementary O-Methylation of Catechols by Using Three-Enzyme Cascades
- (2015) Jutta Siegrist et al. CHEMBIOCHEM
- ‘Dopamine-first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile
- (2015) Benjamin R. Lichman et al. FEBS Journal
- De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast
- (2015) Isis J. Trenchard et al. METABOLIC ENGINEERING
- An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose
- (2015) William C DeLoache et al. Nature Chemical Biology
- RRDistMaps: a UCSF Chimera tool for viewing and comparing protein distance maps
- (2014) J. E. Chen et al. BIOINFORMATICS
- Asymmetric synthesis of tetrahydroisoquinolines by enzymatic Pictet–Spengler reaction
- (2014) Masakatsu Nishihachijo et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Facile one-pot synthesis of tetrahydroisoquinolines from amino acids via hypochlorite-mediated decarboxylation and Pictet–Spengler condensation
- (2014) Justin J. Maresh et al. TETRAHEDRON LETTERS
- The mechanism of copper uptake by tyrosinase from Bacillus megaterium
- (2013) Margarita Kanteev et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Benzylisoquinoline Alkaloid Metabolism: A Century of Discovery and a Brave New World
- (2013) Jillian M. Hagel et al. PLANT AND CELL PHYSIOLOGY
- The Catalytic Potential ofCoptis japonicaNCS2 Revealed - Development and Utilisation of a Fluorescamine-Based Assay
- (2012) Thomas Pesnot et al. ADVANCED SYNTHESIS & CATALYSIS
- Transaminases for the synthesis of enantiopure beta-amino acids
- (2012) Jens Rudat et al. AMB Express
- A bacterial platform for fermentative production of plant alkaloids
- (2011) Akira Nakagawa et al. Nature Communications
- Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols
- (2010) Stefano M. Marino et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- First Structures of an Active Bacterial Tyrosinase Reveal Copper Plasticity
- (2010) Mor Sendovski et al. JOURNAL OF MOLECULAR BIOLOGY
- Calcium-Promoted Pictet-Spengler Reactions of Ketones and Aldehydes
- (2010) Matthew J. Vanden Eynden et al. JOURNAL OF ORGANIC CHEMISTRY
- Molecular and biochemical characterization of a distinct tyrosinase involved in melanin production from Aeromonas media
- (2008) Xia Wan et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae
- (2008) Kristy M Hawkins et al. Nature Chemical Biology
- Microbial production of plant benzylisoquinoline alkaloids
- (2008) H. Minami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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