Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum

A dysbiotic microbiome promotes head and neck squamous cell carcinoma

(2022) Daniel N. Frank et al.   ONCOGENE

Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice

(2021) Rabia Moentadj et al.   ANNALS OF THE RHEUMATIC DISEASES

Individuals at risk for rheumatoid arthritis harbor differential intestinal bacteriophage communities with distinct metabolic potential

(2021) Mihnea R. Mangalea et al.   Cell Host & Microbe

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis

(2021) Vinod K. Gupta et al.   Genome Medicine

Identification of Novel, Immunogenic HLA‐DR‐Presented Prevotella copri Peptides in Patients with Rheumatoid Arthritis

(2021) Annalisa Pianta et al.   Arthritis & Rheumatology

Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data

(2020) Jasmine Chong et al.   Nature Protocols

The importance of differences; On environment and its interactions with genes and immunity in the causation of rheumatoid arthritis

(2020) L. Klareskog et al.   JOURNAL OF INTERNAL MEDICINE

Functional and Genomic Variation between Human-Derived Isolates of Lachnospiraceae Reveals Inter- and Intra-Species Diversity

(2020) Matthew T. Sorbara et al.   Cell Host & Microbe

Dysbiosis in the oral microbiomes of anti-CCP positive individuals at risk of developing rheumatoid arthritis

(2020) Zijian Cheng et al.   ANNALS OF THE RHEUMATIC DISEASES

Affinity Maturation of the Anti–Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis

(2019) Sarah Kongpachith et al.   Arthritis & Rheumatology

Prevotella copri in individuals at risk for rheumatoid arthritis

(2019) Deshire Alpizar-Rodriguez et al.   ANNALS OF THE RHEUMATIC DISEASES

Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection

(2019) Sam X. Li et al.   PLoS Pathogens

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

(2019) Mark Asquith et al.   Arthritis & Rheumatology

Timing of elevations of autoantibody isotypes in rheumatoid arthritis prior to disease diagnosis

(2019) Lindsay B. Kelmenson et al.   Arthritis & Rheumatology

T cell-dependent affinity maturation and innate immune pathways differentially drive autoreactive B cell responses in rheumatoid arthritis

(2018) Daniel R. Lu et al.   Arthritis & Rheumatology

Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis

(2018) M. Kristen Demoruelle et al.   Arthritis & Rheumatology

Affinity Maturation Drives Epitope Spreading and Generation of Pro-inflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis

(2018) Serra E. Elliott et al.   Arthritis & Rheumatology

Modulation of Inflammatory Arthritis in Mice by Gut Microbiota Through Mucosal Inflammation and Autoantibody Generation

(2018) Widian K. Jubair et al.   Arthritis & Rheumatology

Attenuation of Rheumatoid Inflammation by Sodium Butyrate Through Reciprocal Targeting of HDAC2 in Osteoclasts and HDAC8 in T Cells

(2018) Da Som Kim et al.   Frontiers in Immunology

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

(2018) V. Michael Holers et al.   Nature Reviews Rheumatology

Human plasma cell derived monoclonal antibodies to post-translationally modified proteins recognize amino acid motifs rather than specific proteins

(2018) Johanna Steen et al.   Arthritis & Rheumatology

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

(2018) Taylor K. Soderborg et al.   Nature Communications

An exploration of Prevotella-rich microbiomes in HIV and men who have sex with men

(2018) Abigail J. S. Armstrong et al.   Microbiome

Fight them or feed them: how the intestinal mucus layer manages the gut microbiota

(2018) Bjoern O Schroeder   Gastroenterology Report

Two rheumatoid arthritis–specific autoantigens correlate microbial immunity with autoimmune responses in joints

(2017) Annalisa Pianta et al.   JOURNAL OF CLINICAL INVESTIGATION

Bacteroidales recruit IL-6-producing intraepithelial lymphocytes in the colon to promote barrier integrity

(2017) K A Kuhn et al.   Mucosal Immunology

Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis

(2017) Mark Asquith et al.   Arthritis & Rheumatology

Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients

(2017) M. Kristen Demoruelle et al.   Arthritis & Rheumatology

Evidence of the Immune Relevance of Prevotella copri , a Gut Microbe, in Patients With Rheumatoid Arthritis

(2017) Annalisa Pianta et al.   Arthritis & Rheumatology

Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

(2016) M. F. Konig et al.   Science Translational Medicine

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

(2016) Jun Chen et al.   Genome Medicine

Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis

(2016) Jennifer D. Kinslow et al.   Arthritis & Rheumatology

Perturbed Mucosal Immunity and Dysbiosis Accompany Clinical Disease in a Rat Model of Spondyloarthritis

(2016) Mark J. Asquith et al.   Arthritis & Rheumatology

Role of the Gut Microbiome in Modulating Arthritis Progression in Mice

(2016) Xiaofei Liu et al.   Scientific Reports

Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis

(2015) Priscilla F Kerkman et al.   ANNALS OF THE RHEUMATIC DISEASES

Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs

(2015) Elisa Corsiero et al.   ANNALS OF THE RHEUMATIC DISEASES

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

(2015) Malin E.V. Johansson et al.   Cell Host & Microbe

The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

(2015) Xuan Zhang et al.   NATURE MEDICINE

The IL-23–IL-17 axis in inflammatory arthritis

(2015) Erik Lubberts   Nature Reviews Rheumatology

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome

(2015) Sara Omenetti et al.   Frontiers in Immunology

Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APCMin/+ Mice

(2015) Joshua S. Son et al.   PLoS One

Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine

(2015) Daniel N. Frank et al.   PLoS One

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination

(2014) Yann-Chong Tan et al.   CLINICAL IMMUNOLOGY

A Phylogenomic View of Ecological Specialization in the Lachnospiraceae, a Family of Digestive Tract-Associated Bacteria

(2014) Conor J. Meehan et al.   Genome Biology and Evolution

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

(2014) Yi Yang et al.   NATURE

Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis

(2014) Yann-Chong Tan et al.   Arthritis & Rheumatology

Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease

(2014) Jose U. Scher et al.   Arthritis & Rheumatology

Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data

(2013) C. E. Robertson et al.   BIOINFORMATICS

Induction of Diabetes in the RIP-B7.1 Mouse Model Is Critically Dependent on TLR3 and MyD88 Pathways and Is Associated With Alterations in the Intestinal Microbiome

(2013) A. K. Alkanani et al.   DIABETES

Peripheral education of the immune system by the colonic microbiota

(2013) Kristine A. Kuhn et al.   SEMINARS IN IMMUNOLOGY

Periodontal disease, Porphyromonas gingivalis, and rheumatoid arthritis: what triggers autoimmunity and clinical disease?

(2013) Jose U Scher et al.   ARTHRITIS RESEARCH & THERAPY

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

(2012) Danielle M Gerlag et al.   ANNALS OF THE RHEUMATIC DISEASES

SINA: Accurate high-throughput multiple sequence alignment of ribosomal RNA genes

(2012) Elmar Pruesse et al.   BIOINFORMATICS

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

(2012) Jeremy Sokolove et al.   PLoS One

Isolated Lymphoid Follicles are Dynamic Reservoirs for the Induction of Intestinal IgA

(2012) Kathryn A. Knoop et al.   Frontiers in Immunology

Antibodies against cyclic citrullinated peptides of IgG, IgA and IgM isotype and rheumatoid factor of IgM and IgA isotype are increased in unaffected members of multicase rheumatoid arthritis families from northern Sweden

(2011) Lisbeth Ärlestig et al.   ANNALS OF THE RHEUMATIC DISEASES

Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data

(2011) T. Carver et al.   BIOINFORMATICS

The Th17/Treg imbalance and cytokine environment in peripheral blood of patients with rheumatoid arthritis

(2011) Wenhong Wang et al.   RHEUMATOLOGY INTERNATIONAL

Spatial organization of intestinal microbiota in the mouse ascending colon

(2010) Gerardo M Nava et al.   ISME Journal

Th17 cells can provide B cell help in autoantibody induced arthritis

(2010) Cynthia L. Hickman-Brecks et al.   JOURNAL OF AUTOIMMUNITY

Periodontitis in RA—the citrullinated enolase connection

(2010) Karin Lundberg et al.   Nature Reviews Rheumatology

A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA

(2009) Jason R. Kolfenbach et al.   ARTHRITIS AND RHEUMATISM

ABySS: A parallel assembler for short read sequence data

(2009) J. T. Simpson et al.   GENOME RESEARCH