Affinity Maturation of the Anti–Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis

Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension

(2018) Lisa K. Blum et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T cell-dependent affinity maturation and innate immune pathways differentially drive autoreactive B cell responses in rheumatoid arthritis

(2018) Daniel R. Lu et al.   Arthritis & Rheumatology

Affinity Maturation Drives Epitope Spreading and Generation of Pro-inflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis

(2018) Serra E. Elliott et al.   Arthritis & Rheumatology

VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans

(2017) Nitya Nair et al.   Science Translational Medicine

Autoantibodies From Single Circulating Plasmablasts React With Citrullinated Antigens andPorphyromonas gingivalisin Rheumatoid Arthritis

(2016) Song Li et al.   Arthritis & Rheumatology

Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis

(2016) Jennifer D. Kinslow et al.   Arthritis & Rheumatology

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data: Table 1.

(2015) Namita T. Gupta et al.   BIOINFORMATICS

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination

(2014) Yann-Chong Tan et al.   CLINICAL IMMUNOLOGY

Citrullinated Autoantigens: From Diagnostic Markers to Pathogenetic Mechanisms

(2014) Sylviane Muller et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis

(2014) Yann-Chong Tan et al.   Arthritis & Rheumatology

Systematic Review: Accuracy of Anti–Citrullinated Peptide Antibodies for Diagnosing Rheumatoid Arthritis

(2013) Penny F. Whiting   ANNALS OF INTERNAL MEDICINE

Fine specificity of anti-citrullinated peptide antibodies discloses a heterogeneous antibody population in rheumatoid arthritis

(2013) J. D. Goules et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface

(2012) Giovanni Di Zenzo et al.   JOURNAL OF CLINICAL INVESTIGATION

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

(2012) Jeremy Sokolove et al.   PLoS One

Cross-reactivity of a human IgG1anticitrullinated fibrinogen monoclonal antibody to a citrullinated profilaggrin peptide

(2012) Nicole Hartwig Trier et al.   PROTEIN SCIENCE

Central B-Cell Tolerance: Where Selection Begins

(2012) R. Pelanda et al.   Cold Spring Harbor Perspectives in Biology

Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis

(2011) Lotte A. van de Stadt et al.   ARTHRITIS AND RHEUMATISM

Anti-CCP antibodies: the past, the present and the future

(2011) Walther J. van Venrooij et al.   Nature Reviews Rheumatology

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

(2010) A. Ioan-Facsinay et al.   ANNALS OF THE RHEUMATIC DISEASES

Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity

(2010) Wenzhong Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Progression of joint damage in early rheumatoid arthritis: Association with HLA–DRB1, rheumatoid factor, and anti–citrullinated protein antibodies in relation to different treatment strategies

(2008) J. K. de Vries-Bouwstra et al.   ARTHRITIS AND RHEUMATISM

IgTree©: Creating Immunoglobulin variable region gene lineage trees

(2008) Michal Barak et al.   JOURNAL OF IMMUNOLOGICAL METHODS