N-heterocyclic carbene-catalyzed atroposelective synthesis of axially chiral 5-aryl 2-pyrones from enals

Asymmetric Carbene‐Catalyzed Oxidation of Functionalized Aldimines as 1,4‐Dipoles

(2021) Guanjie Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hexadehydro-Diels–Alder Reaction: Benzyne Generation via Cycloisomerization of Tethered Triynes

(2021) Lucas L. Fluegel et al.   CHEMICAL REVIEWS

N‐Heterocyclic Carbene‐Catalyzed Atroposelective Annulation for Access to Thiazine Derivatives with C‐N Axial Chirality

(2021) Tingting Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

o-Silylaryl Triflates: A Journey of Kobayashi Aryne Precursors

(2021) Jiarong Shi et al.   CHEMICAL REVIEWS

NHC‐Catalyzed Desymmetrization of N‐Aryl Maleimides Leading to the Atroposelective Synthesis of N‐Aryl Succinimides

(2021) Soumen Barik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Axially Chiral Benzothiophene/Benzofuran‐Fused Biaryls by N‐Heterocyclic Carbene Catalyzed Arene Formation

(2021) Chun‐Lin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atroposelective Synthesis of Axially Chiral 4-Aryl α-Carbolines via N-Heterocyclic Carbene Catalysis

(2021) Rui Ma et al.   ORGANIC LETTERS

Carbene-Catalyzed Atroposelective Annulation and Desymmetrization of Urazoles

(2021) Jiamiao Jin et al.   ORGANIC LETTERS

Carbene‐Catalyzed Asymmetric Construction of Atropisomers

(2021) Runjiang Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2-Pyrones with Alkynes

(2021) Meng-Meng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbene-catalyzed activation of cyclopropylcarbaldehydes for mannich reaction and δ-lactam formation: remote enantioselecitvity control and dynamic kinetic asymmetric transformation

(2021) Jie Lv et al.   Science China-Chemistry

Asymmetric synthesis of atropisomers snabled by N-Heterocyclic carbene satalysis

(2021) Jie Feng et al.   TETRAHEDRON

N-heterocyclic carbene-catalyzed arene formation reactions

(2021) Tingting Li et al.   Science China-Chemistry

Recent Progress toward the Construction of Axially Chiral Molecules Catalyzed by an N-heterocyclic Carbene

(2021) Jiaming Wang et al.   ACS Catalysis

Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids

(2020) Guanjie Wang et al.   Nature Communications

Bifunctional N-Heterocyclic Carbenes Derived from l-Pyroglutamic Acid and Their Applications in Enantioselective Organocatalysis

(2020) Xiang-Yu Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

N ‐Heterocyclic carbene organocatalysis: activation modes and typical reactive intermediates

(2020) Xingkuan Chen et al.   CHINESE JOURNAL OF CHEMISTRY

Enantioselective Synthesis of cis‐Decalin Derivatives by the Inverse‐Electron‐Demand Diels–Alder Reaction of 2‐Pyrones

(2020) Quan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene-Based Catalysis Enabling Cross-Coupling Reactions

(2020) Hirohisa Ohmiya   ACS Catalysis

N-heterocyclic carbene-catalyzed radical reactions

(2020) Kun-Quan Chen et al.   Science China-Chemistry

NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles

(2019) Santigopal Mondal et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cyclic Alkyne Approach to Heteroatom-Containing Polycyclic Aromatic Hydrocarbon Scaffolds

(2019) Evan Darzi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modular Synthesis of Unsymmetrical Doubly-ring-fused Benzene Derivatives Based on a Sequential Ring Construction Strategy Using Oxadiazinones as a Platform Molecule

(2019) Tomohiro Meguro et al.   CHEMISTRY LETTERS

NHC-Catalyzed Atroposelective Acylation of Phenols: Access to Enantiopure NOBIN Analogs by Desymmetrization

(2019) Shenci Lu et al.   ORGANIC LETTERS

NHC-catalyzed atropoenantioselective synthesis of axially chiral biaryl amino alcohols via a cooperative strategy

(2019) Gongming Yang et al.   Nature Communications

A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki–Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers

(2019) Di Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atroposelective Arene Formation by Carbene-Catalyzed Formal [4+2] Cycloaddition

(2019) Ke Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uncovering the Neglected Similarities of Arynes and Donor-Acceptor Cyclopropanes

(2019) Daniel B. Werz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalysis via Azolium Dienolates: An Efficient Strategy for Remote Enantioselective Functionalizations

(2018) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to Enantioenriched Organosilanes from Enals and β-Silyl Enones: Carbene Organocatalysis

(2018) Yuxia Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in molecular rearrangements involving aryne intermediates

(2018) Tony Roy et al.   CHEMICAL COMMUNICATIONS

Binaphthyl–Bipyridyl Cyclic Dyads as a Chiroptical Switch

(2018) Kazuto Takaishi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective [3+3] atroposelective annulation catalyzed by N-heterocyclic carbenes

(2018) Changgui Zhao et al.   Nature Communications

Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi

(2017) Andre Gustavo Tempone et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Employing Arynes in Diels–Alder Reactions and Transition-Metal-Free Multicomponent Coupling and Arylation Reactions

(2016) Sachin Suresh Bhojgude et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of biaryls using aryne intermediates

(2016) José-Antonio García-López et al.   CHEMICAL SOCIETY REVIEWS

A chemically powered unidirectional rotary molecular motor based on a palladium redox cycle

(2016) Beatrice S. L. Collins et al.   Nature Chemistry

Artificial Molecular Machines

(2015) Sundus Erbas-Cakmak et al.   CHEMICAL REVIEWS

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Stronger Brønsted Acids: Recent Progress

(2015) Takahiko Akiyama et al.   CHEMICAL REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

N-Heterocyclic carbene catalysed redox isomerisation of esters to functionalised benzaldehydes

(2015) Lisa Candish et al.   Chemical Science

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective Acylation

(2014) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral phosphines in nucleophilic organocatalysis

(2014) Yumei Xiao et al.   Beilstein Journal of Organic Chemistry

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

NHC Organocatalytic Formal LUMO Activation of α,β-Unsaturated Esters for Reaction with Enamides

(2013) Jiajia Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Catalysis with N-Heterocyclic Carbenes under Oxidative Conditions

(2013) Suman De Sarkar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Annulation of Modified Enals with Enolizable Aldehydes

(2013) Santhivardhana Reddy Yetra et al.   ORGANIC LETTERS

Enantioselective, NHC-Catalyzed Annulations of Trisubstituted Enals and CyclicN-Sulfonylimines via α,β-Unsaturated Acyl Azoliums

(2012) Alberto G. Kravina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed Ireland–Coates Claisen Rearrangement: Synthesis of Functionalized β-Lactones

(2012) Lisa Candish et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A computational study of the origin of stereoinduction in NHC-catalyzed annulation reactions of α,β-unsaturated acyl azoliums

(2012) Eirik Lyngvi et al.   Chemical Science

Chiral N-Heterocyclic Carbene-Catalyzed Annulations of Enals and Ynals with Stable Enols: A Highly Enantioselective Coates–Claisen Rearrangement

(2012) Jessada Mahatthananchai et al.   ACS Catalysis

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structures, Reactivities, and Antibiotic Properties of the Marinopyrroles A−F

(2010) Chambers C. Hughes et al.   JOURNAL OF ORGANIC CHEMISTRY

An Enantioselective Claisen Rearrangement Catalyzed by N-Heterocyclic Carbenes

(2010) Juthanat Kaeobamrung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS