Carbene-Catalyzed Atroposelective Annulation and Desymmetrization of Urazoles

N‐Heterocyclic Carbene‐Catalyzed Atroposelective Annulation for Access to Thiazine Derivatives with C‐N Axial Chirality

(2021) Tingting Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC‐Catalyzed Desymmetrization of N‐Aryl Maleimides Leading to the Atroposelective Synthesis of N‐Aryl Succinimides

(2021) Soumen Barik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Axially Chiral Benzothiophene/Benzofuran‐Fused Biaryls by N‐Heterocyclic Carbene Catalyzed Arene Formation

(2021) Chun‐Lin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereochemistry and Recent Applications of Axially Chiral Organic Molecules.

(2020) Michele Mancinelli et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Organocatalyzed Arene Formation: Application in Atroposelective Synthesis of Polysubstituted Benzenes

(2020) Ke Xu et al.   SYNLETT

Asymmetric Synthesis of Axially Chiral Phosphamides via Atroposelective N-Allylic Alkylation

(2020) Guo-Hui Yang et al.   ACS Catalysis

N‐Heterocyclic Carbene‐Catalyzed Activation of Ynals for the Construction of Functional Pyridines

(2020) Jia‐Hui Li et al.   Asian Journal of Organic Chemistry

Enantioselective Synthesis of Atropisomers with Multiple Stereogenic Axes

(2020) Xiaoze Bao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N ‐Heterocyclic carbene organocatalysis: activation modes and typical reactive intermediates

(2020) Xingkuan Chen et al.   CHINESE JOURNAL OF CHEMISTRY

Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry

(2020) Chiara Brullo et al.   MOLECULES

Isothiourea-Catalyzed Atroposelective N-Acylation of Sulfonamides

(2020) Jun-Yang Ong et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Methodologies towards the Synthesis of Atropisomeric N-Heterocycles

(2020) Vasco Corti et al.   SYNTHESIS-STUTTGART

Atroposelective Access to Oxindole-Based Axially Chiral Styrenes via the Strategy of Catalytic Kinetic Resolution

(2020) Chun Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Atroposelective Oxidative C–H/C–H Cross-Coupling Reaction of 1-Aryl Isoquinoline Derivatives with Electron-Rich Heteroarenes

(2020) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis

(2019) Evijola Llabani et al.   Nature Chemistry

Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

(2019) Shenci Lu et al.   Nature Communications

Atroposelective Arene Formation by Carbene-Catalyzed Formal [4+2] Cycloaddition

(2019) Ke Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent encounters with atropisomerism in drug discovery

(2018) Peter W. Glunz   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Heterocyclic carbene-catalyzed annulation of ynals with amidines: access to 1,2,6-trisubstituted pyrimidin-4-ones

(2018) Yangxi Xie et al.   CHEMICAL COMMUNICATIONS

A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

(2018) Kathleen J. R. Murauski et al.   CHEMICAL SOCIETY REVIEWS

A Bird's Eye View of Atropisomers Featuring a Five-Membered Ring

(2018) Damien Bonne et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) β Inhibitor

(2018) Jayaraman Chandrasekhar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective [3+3] atroposelective annulation catalyzed by N-heterocyclic carbenes

(2018) Changgui Zhao et al.   Nature Communications

Catalyst-Controlled Stereoselective Synthesis of Atropisomers

(2018) Bouthayna Zilate et al.   ACS Catalysis

N-Heterocyclic Carbene-Catalyzed in situ Activation of Alkynyl Acids for C-S Bond Formation: Access to Imidazo[2,1-b][1,3]thiazinones

(2018) Ding Du et al.   ADVANCED SYNTHESIS & CATALYSIS

Atroposelective Catalytic Asymmetric Allylic Alkylation Reaction for Axially Chiral Anilides with Achiral Morita–Baylis–Hillman Carbonates

(2018) Shou-Lei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Access to All-Carbon Spirocycles through a Carbene and Thiourea Cocatalytic Desymmetrization Cascade Reaction

(2018) Shitian Zhuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unravelling Synthesis and Chemistry of Stable, Acyclic and Double-Deficient 1,3-Butadienes: An endo-selective Diels-Alder Route to Hedgehog Pathway Inhibitors

(2018) Kamal Kumar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Participation of β-Ketothioamides in N-Heterocyclic Carbene-Catalyzed [3 + 3] Spiroannulation: Asymmetric Synthesis of Functionalized Spiro-piperidinone Derivatives

(2018) Hong Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrochemical synthesis of diverse sulfonamide derivatives depending on the potential electrode and their antimicrobial activity evaluation

(2017) F. Varmaghani et al.   NEW JOURNAL OF CHEMISTRY

Esters as Alkynyl Acyl Ammonium and Azolium Precursors: A Formal [2 + 3] Annulation with Amidomalonates via Lewis Base/Lewis Acid Cooperative Catalysis

(2017) Jing Cao et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium

(2017) Changhe Zhang et al.   ACS Catalysis

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Preorganization of Atropisomers to Increase Target Selectivity

(2016) Jeffrey Gustafson et al.   SYNLETT

Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

(2016) Ji-Wei Zhang et al.   Nature Communications

N-Heterocyclic Carbene Catalyzed Dynamic Kinetic Resolution of Pyranones

(2015) Changgui Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in asymmetric organocatalysis mediated by bifunctional amine–thioureas bearing multiple hydrogen-bonding donors

(2015) Xin Fang et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

An Efficient and Convenient Approach for the Synthesis of Novel Pyrazolo[1,2-a]triazole-triones and Evaluation of their Antimicrobial Activities

(2014) Pooja Saluja et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Cooperative N-heterocyclic carbene (NHC)–Lewis acid-mediated regioselective umpolung formal [3 + 2] annulations of alkynyl aldehydes with isatins

(2014) Yu Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Task-specific ionic liquid catalyzed synthesis of novel naphthoquinone–urazole hybrids and evaluation of their antioxidant and in vitro anticancer activity

(2014) Pooja Saluja et al.   RSC Advances

Diaminocyclopropenylidene Organocatalysts: Beyond N-Heterocyclic Carbenes

(2013) Stephen J. Connon   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Biological Stereoselectivity of Atropisomeric Natural Products and Drugs

(2013) Arie Zask et al.   CHIRALITY

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Discovery and Characterization of Atropisomer PH-797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate

(2011) Li Xing et al.   ChemMedChem

Catalytic Asymmetric Synthesis of Axially Chiral o-Iodoanilides by Phase-Transfer Catalyzed Alkylations

(2011) Seiji Shirakawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atropisomerism Observed in Indometacin Derivatives

(2011) Hideyo Takahashi et al.   ORGANIC LETTERS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Activation

(2010) Suman De Sarkar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

(Thio)urea organocatalysis—What can be learnt from anion recognition?

(2009) Zhiguo Zhang et al.   CHEMICAL SOCIETY REVIEWS