The substitution at residue 218 of the NS5 protein methyltransferase domain of Tembusu virus impairs viral replication and translation and may triggers RIG-I-like receptor signaling

cis-Acting Sequences and Secondary Structures in Untranslated Regions of Duck Tembusu Virus RNA Are Important for Cap-Independent Translation and Viral Proliferation

(2020) Tao Wang et al.   JOURNAL OF VIROLOGY

Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase

(2020) Rostom Ahmed-Belkacem et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Genetically stable reporter virus, subgenomic replicon and packaging system of duck Tembusu virus based on a reverse genetics system

(2019) Yu He et al.   VIROLOGY

Binding of the Duck Tembusu Virus Protease to STING Is Mediated by NS2B and Is Crucial for STING Cleavage and for Impaired Induction of IFN-β

(2019) Zhen Wu et al.   JOURNAL OF IMMUNOLOGY

Establishment of reverse genetics system for duck Tembusu virus to study virulence and screen antiviral genes

(2018) Shun Chen et al.   ANTIVIRAL RESEARCH

Evolution of Tembusu Virus in Ducks, Chickens, Geese, Sparrows, and Mosquitoes in Northern China

(2018) Guanliu Yu et al.   Viruses-Basel

An updated review of avian-origin Tembusu virus: a newly emerging avian Flavivirus

(2017) Wei Zhang et al.   JOURNAL OF GENERAL VIROLOGY

Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations

(2017) Yazan M. Abbas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo RNA synthesis catalyzed by the Zika Virus RNA polymerase domain

(2017) Christina Calmels et al.   Scientific Reports

Causes and Consequences of Flavivirus RNA Methylation

(2017) Shelton S. Bradrick   Frontiers in Microbiology

A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

(2017) Yujiao Yang et al.   EBioMedicine

Flavivirus RNA transactions from viral entry to genome replication

(2016) Mariano A. Garcia-Blanco et al.   ANTIVIRAL RESEARCH

Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA

(2016) Junyong Wang et al.   JOURNAL OF IMMUNOLOGY

Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

(2016) Swapnil C. Devarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evasion of early innate immune response by 2′- O -methylation of dengue genomic RNA

(2016) David C. Chang et al.   VIROLOGY

Zika Virus Replicons for Drug Discovery

(2016) Xuping Xie et al.   EBioMedicine

Identification and molecular characterization of a novel duck Tembusu virus isolate from Southwest China

(2015) Kesen Zhu et al.   ARCHIVES OF VIROLOGY

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA

(2015) Christine Schuberth-Wagner et al.   IMMUNITY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

(2015) Yongqian Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of age and inoculation route on the infection of duck Tembusu virus in Goslings

(2015) Jinfeng Ti et al.   VETERINARY MICROBIOLOGY

Flaviviral Replication Complex: Coordination between RNA Synthesis and 5’-RNA Capping

(2015) Valerie Klema et al.   Viruses-Basel

Flavivirus RNA methylation

(2014) H. Dong et al.   JOURNAL OF GENERAL VIROLOGY

Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

(2014) G. E. Katibah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ifit1 Inhibits Japanese Encephalitis Virus Replication through Binding to 5' Capped 2'-O Unmethylated RNA

(2013) T. Kimura et al.   JOURNAL OF VIROLOGY

Rational Design of a Flavivirus Vaccine by Abolishing Viral RNA 2'-O Methylation

(2013) S.-H. Li et al.   JOURNAL OF VIROLOGY

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs

(2013) P. Kumar et al.   NUCLEIC ACIDS RESEARCH

Duck egg drop syndrome virus: an emerging Tembusu-related flavivirus in China

(2013) PeiPei Liu et al.   Science China-Life Sciences

Tembusu Virus in Human, China

(2013) Y. Tang et al.   Transboundary and Emerging Diseases

Molecular characterization of a duck Tembusu virus from China

(2013) XiaoFei Bai et al.   VIRUS GENES

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

(2013) Matthias Habjan et al.   PLoS Pathogens

Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques

(2013) Roland Züst et al.   PLoS Pathogens

Selective inhibition of the West Nile virus methyltransferase by nucleoside analogs

(2012) Hui Chen et al.   ANTIVIRAL RESEARCH

Adapted Tembusu-Like Virus in Chickens and Geese in China

(2012) M. Liu et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Complete Genomic Sequence of Duck Flavivirus from China

(2012) M. Liu et al.   JOURNAL OF VIROLOGY

Streaming fragment assignment for real-time analysis of sequencing experiments

(2012) Adam Roberts et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Identification and molecular characterization of a novel flavivirus isolated from geese in China

(2012) Xinmei Huang et al.   RESEARCH IN VETERINARY SCIENCE

Characterization of a Tembusu Virus Isolated from Naturally Infected House Sparrows (Passer domesticus) in Northern China

(2012) Y. Tang et al.   Transboundary and Emerging Diseases

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

The Endoplasmic Reticulum Provides the Membrane Platform for Biogenesis of the Flavivirus Replication Complex

(2010) Leah K. Gillespie et al.   JOURNAL OF VIROLOGY

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Biochemical and genetic characterization of dengue virus methyltransferase

(2010) Hongping Dong et al.   VIROLOGY