Binding of the Duck Tembusu Virus Protease to STING Is Mediated by NS2B and Is Crucial for STING Cleavage and for Impaired Induction of IFN-β

IRF7 Is Involved in Both STING and MAVS Mediating IFN-β Signaling in IRF3-Lacking Chickens

(2019) Yuqiang Cheng et al.   JOURNAL OF IMMUNOLOGY

Establishment of reverse genetics system for duck Tembusu virus to study virulence and screen antiviral genes

(2018) Shun Chen et al.   ANTIVIRAL RESEARCH

Duck interferon regulatory factor 7 (IRF7) can control duck Tembusu virus (DTMUV) infection by triggering type I interferon production and its signal transduction pathway

(2018) Shun Chen et al.   CYTOKINE

Duck stimulator of interferon genes plays an important role in host anti-duck plague virus infection through an IFN-dependent signalling pathway

(2018) Shun Chen et al.   CYTOKINE

Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

(2018) Qiang Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved Active-Site Residues Associated with OAS Enzyme Activity and Ubiquitin-Like Domains Are Not Required for the Antiviral Activity of goOASL Protein against Avian Tembusu Virus

(2018) Shun Chen et al.   Viruses-Basel

Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir

(2018) Alex C Stabell et al.   eLife

The Unique Cofactor Region of Zika Virus NS2B–NS3 Protease Facilitates Cleavage of Key Host Proteins

(2018) Maureen E. Hill et al.   ACS Chemical Biology

An updated review of avian-origin Tembusu virus: a newly emerging avian Flavivirus

(2017) Wei Zhang et al.   JOURNAL OF GENERAL VIROLOGY

Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB

(2017) Jing Ye et al.   JOURNAL OF VIROLOGY

Differential immune-related gene expression in the spleens of duck Tembusu virus-infected goslings

(2017) Yu He et al.   VETERINARY MICROBIOLOGY

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

(2017) Shun Chen et al.   Viruses-Basel

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

(2017) Sebastian Aguirre et al.   Nature Microbiology

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

Molecular cloning and functional characterization of duck mitochondrial antiviral-signaling protein (MAVS)

(2016) Huilin Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA

(2016) Junyong Wang et al.   JOURNAL OF IMMUNOLOGY

Identification of2′-5′-Oligoadenylate Synthetase-LikeGene in Goose: Gene Structure, Expression Patterns, and Antiviral Activity Against Newcastle Disease Virus

(2016) Chao Yang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Emerging Duck Flavivirus Is Not Pathogenic for Primates and Is Highly Sensitive to Mammalian Interferon Antiviral Signaling

(2016) Hong-Jiang Wang et al.   JOURNAL OF VIROLOGY

Duck Tembusu Virus Exhibits Pathogenicity to Kunming Mice by Intracerebral Inoculation

(2016) Jinfeng Ti et al.   Frontiers in Microbiology

Identification and molecular characterization of a novel duck Tembusu virus isolate from Southwest China

(2015) Kesen Zhu et al.   ARCHIVES OF VIROLOGY

Porcine Epidemic Diarrhea Virus 3C-Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO

(2015) Dang Wang et al.   JOURNAL OF VIROLOGY

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

(2015) S. Liu et al.   SCIENCE

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

(2015) Nadine A. Dalrymple et al.   mBio

Enterovirus 2Apro Targets MDA5 and MAVS in Infected Cells

(2014) Q. Feng et al.   JOURNAL OF VIROLOGY

Tembusu Virus in Human, China

(2013) Y. Tang et al.   Transboundary and Emerging Diseases

Duck Tembusu virus exhibits neurovirulence in BALB/c mice

(2013) Shuang Li et al.   Virology Journal

Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity

(2012) Sayuri Nitta et al.   HEPATOLOGY

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

(2012) Y. Tanaka et al.   Science Signaling

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

(2012) Chia-Yi Yu et al.   PLoS Pathogens

STING is a direct innate immune sensor of cyclic di-GMP

(2011) Dara L. Burdette et al.   NATURE

Duck Egg-Drop Syndrome Caused by BYD Virus, a New Tembusu-Related Flavivirus

(2011) Jingliang Su et al.   PLoS One

An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China

(2011) Pixi Yan et al.   VIROLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

(2009) Andrea Ablasser et al.   NATURE IMMUNOLOGY

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

Interferon Regulatory Factor IRF-7 Induces the Antiviral Alpha Interferon Response and Protects against Lethal West Nile Virus Infection

(2008) S. Daffis et al.   JOURNAL OF VIROLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE