Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3

(2022) Ziwen Pan et al.   Molecular Cancer

Cancer exosomes and natural killer cells dysfunction: biological roles, clinical significance and implications for immunotherapy

(2022) Reza Hosseini et al.   Molecular Cancer

Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications

(2022) Guangpeng He et al.   Molecular Cancer

Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness

(2022) Chaoyi Chen et al.   Molecular Cancer

Dual role of ARPC1B in regulating the network between tumor-associated macrophages and tumor cells in glioblastoma

(2022) Tianqi Liu et al.   OncoImmunology

Frontiers in the treatment of glioblastoma: Past, present and emerging

(2021) Taskeen Iqbal Janjua et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor‐associated macrophages in immunotherapy

(2021) Shijia Yan et al.   FEBS Journal

Redirecting macrophage function to sustain their “defender” antitumor activity

(2021) Stephanie L. Tzetzo et al.   CANCER CELL

Cbl-b deficiency prevents functional but not phenotypic T cell anergy

(2021) Trang T.T. Nguyen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

(2021) Ana Rita Pombo Antunes et al.   NATURE NEUROSCIENCE

Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction

(2021) Jianye Xu et al.   Cell Death & Disease

CBLB ablation with CRISPR/Cas9 enhances cytotoxicity of human placental stem cell-derived NK cells for cancer immunotherapy

(2021) Xuan Guo et al.   Journal for ImmunoTherapy of Cancer

Nanocomplex‐Mediated In Vivo Programming to Chimeric Antigen Receptor‐M1 Macrophages for Cancer Therapy

(2021) Mikyung Kang et al.   ADVANCED MATERIALS

Brain and other central nervous system tumor statistics, 2021

(2021) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy

(2021) Yujue Wang et al.   CANCER CELL

Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

(2021) Samantha M. Morrissey et al.   Cell Metabolism

Prior nasal delivery of antagomiR-122 prevents radiation-induced brain injury

(2021) Haihong Zhou et al.   MOLECULAR THERAPY

Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells

(2021) Wei Qiu et al.   MOLECULAR THERAPY

The Interplay between Glioblastoma and Its Microenvironment

(2021) Mark Dapash et al.   Cells

Glioma: molecular signature and crossroads with tumor microenvironment

(2021) Lennart Barthel et al.   CANCER AND METASTASIS REVIEWS

Emerging role of tumor-derived extracellular vesicles in T cell suppression and dysfunction in the tumor microenvironment

(2021) Feiya Ma et al.   Journal for ImmunoTherapy of Cancer

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Exosomal noncoding RNAs in Glioma: biological functions and potential clinical applications

(2020) Jian Cheng et al.   Molecular Cancer

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transfer of microRNA via Macrophage-Derived Extracellular Vesicles Promotes Proneural-to-Mesenchymal Transition in Glioma Stem Cells

(2020) Zongpu Zhang et al.   Cancer Immunology Research

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

(2020) Ayuko Hoshino et al.   CELL

Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing

(2020) Xin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ERK signalling: a master regulator of cell behaviour, life and fate

(2020) Hugo Lavoie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery

(2020) Yuqiong Xia et al.   ADVANCED MATERIALS

Macrophage-based approaches for cancer immunotherapy

(2020) Nicholas R. Anderson et al.   CANCER RESEARCH

Challenges to curing primary brain tumours

(2019) Kenneth Aldape et al.   Nature Reviews Clinical Oncology

Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

(2019) Peiwen Chen et al.   CANCER CELL

miR‐122‐5p promotes aggression and epithelial‐mesenchymal transition in triple‐negative breast cancer by suppressing charged multivesicular body protein 3 through mitogen‐activated protein kinase signaling

(2019) Zheng Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma

(2019) Virginie Vignard et al.   Cancer Immunology Research

CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies

(2017) Kaosheng Lv et al.   GENES & DEVELOPMENT

An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

(2017) Yang Li et al.   Nature Communications

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

(2017) Yun Teng et al.   Nature Communications

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

(2017) Akiko Takahashi et al.   Nature Communications

Exosome secretion is a key pathway for clearance of pathological TDP-43

(2016) Yohei Iguchi et al.   BRAIN

PI3Kγ is a molecular switch that controls immune suppression

(2016) Megan M. Kaneda et al.   NATURE

The cellular and molecular origin of tumor-associated macrophages

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