Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 12, Issue 4, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-04-07
DOI
10.1038/s41419-021-03664-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses
- (2020) Longfei Chen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models
- (2020) Ru Li et al. Nature Communications
- Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation
- (2020) Jianye Xu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Transfer of microRNA via Macrophage-Derived Extracellular Vesicles Promotes Proneural-to-Mesenchymal Transition in Glioma Stem Cells
- (2020) Zongpu Zhang et al. Cancer Immunology Research
- The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target
- (2020) V. Gambardella et al. CANCER TREATMENT REVIEWS
- Origin and Function of Stress-Induced IL-6 in Murine Models
- (2020) Hua Qing et al. CELL
- Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
- (2020) Ayuko Hoshino et al. CELL
- Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/β-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma
- (2020) Wencheng Dai et al. Cell Death & Disease
- What is the burden of proof for tumor mutational burden in gliomas?
- (2020) Mustafa Khasraw et al. NEURO-ONCOLOGY
- Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma
- (2020) Lakshana Sreenivasan et al. Cell Death & Disease
- Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer
- (2019) Tong Liu et al. Molecular Cancer
- Glioblastoma-Derived IL-6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth
- (2019) Jonathan B Lamano et al. CLINICAL CANCER RESEARCH
- Reassessment of Exosome Composition
- (2019) Dennis K. Jeppesen et al. CELL
- Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways
- (2019) Mingyu Qian et al. ONCOGENE
- MicroRNA-155-3p promotes breast cancer progression through down-regulating CADM1
- (2019) Guochao Zhang et al. OncoTargets and Therapy
- MIR155HG is a prognostic biomarker and associated with immune infiltration and immune checkpoint molecules expression in multiple cancers
- (2019) Lirong Peng et al. Cancer Medicine
- Methylation-mediated silencing of miR-133a-3p promotes breast cancer cell migration and stemness via miR-133a-3p/MAML1/DNMT3A positive feedback loop
- (2019) Wanyue Shi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Aggregable Nanoparticles-Enabled Chemotherapy and Autophagy Inhibition Combined with Anti-PD-L1 Antibody for Improved Glioma Treatment
- (2019) Shaobo Ruan et al. NANO LETTERS
- IL6/STAT3 Signaling Orchestrates Premetastatic Niche Formation and Immunosuppressive Traits in Lung
- (2019) Bo Jing et al. CANCER RESEARCH
- Targeting the IL-6/JAK/STAT3 signalling axis in cancer
- (2018) Daniel E. Johnson et al. Nature Reviews Clinical Oncology
- Autophagy during viral infection — a double-edged sword
- (2018) Younho Choi et al. NATURE REVIEWS MICROBIOLOGY
- Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways
- (2018) Xiaofan Guo et al. ONCOGENE
- Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
- (2018) Konrad Gabrusiewicz et al. OncoImmunology
- Dual effect of DLBCL-derived EXOs in lymphoma to improve DC vaccine efficacy in vitro while favor tumorgenesis in vivo
- (2018) Zhenzhen Chen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Primary brain tumours in adults
- (2018) Sarah Lapointe et al. LANCET
- M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer
- (2018) Jingqin Lan et al. CANCER RESEARCH
- Glioma exosomes mediate the expansion and function of myeloid‐derived suppressor cells through microRNA‐29a/ Hbp1 and microRNA‐92a/ Prkar1a pathways
- (2018) Xiaofan Guo et al. INTERNATIONAL JOURNAL OF CANCER
- Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1
- (2018) Zhi-Fa Wen et al. Journal for ImmunoTherapy of Cancer
- Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters
- (2017) Gabor J. Szebeni et al. MEDIATORS OF INFLAMMATION
- Hypoxia in the glioblastoma microenvironment: shaping the phenotype of cancer stem-like cells
- (2017) Nicole Colwell et al. NEURO-ONCOLOGY
- Blocking MIR155HG/miR-155 axis inhibits mesenchymal transition in glioma
- (2017) Xuechao Wu et al. NEURO-ONCOLOGY
- The role of exosomes in cancer metastasis
- (2017) Teresa Bernadette Steinbichler et al. SEMINARS IN CANCER BIOLOGY
- A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway
- (2016) Hao Xue et al. Autophagy
- Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype
- (2016) Ling Li et al. CANCER RESEARCH
- Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
- (2016) Mercedes Tkach et al. CELL
- The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
- (2016) Nicole E. Scharping et al. IMMUNITY
- CREBRF is a potent tumor suppressor of glioblastoma by blocking hypoxia-induced autophagy via the CREB3/ATG5 pathway
- (2016) Hao Xue et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- MicroRNA-155-3p promotes hepatocellular carcinoma formation by suppressing FBXW7 expression
- (2016) Bo Tang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The role of microglia and macrophages in glioma maintenance and progression
- (2016) Dolores Hambardzumyan et al. NATURE NEUROSCIENCE
- Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
- (2016) Christine E. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR
- (2016) Xiaofan Guo et al. Oncotarget
- Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization
- (2015) Kun Liu et al. Autophagy
- Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
- (2015) Wenchao Zhou et al. NATURE CELL BIOLOGY
- Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization
- (2014) Min Yang et al. Molecular Cancer
- Self-consumption: the interplay of autophagy and apoptosis
- (2014) Guillermo Mariño et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells
- (2013) Hiroko Tadokoro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway
- (2012) Rui Kang et al. Autophagy
- Hypoxic enhancement of exosome release by breast cancer cells
- (2012) Hamish W King et al. BMC CANCER
- Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway
- (2012) X.-z. Ye et al. JOURNAL OF IMMUNOLOGY
- Exosomes and Cancer: A Newly Described Pathway of Immune Suppression
- (2011) H.-G. Zhang et al. CLINICAL CANCER RESEARCH
- The brain tumor microenvironment
- (2011) Nikki A. Charles et al. GLIA
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Malignant Gliomas in Adults
- (2008) Patrick Y. Wen et al. NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More