Human NOP2/NSUN1 regulates ribosome biogenesis through non-catalytic complex formation with box C/D snoRNPs

Mitochondrial RNA modifications shape metabolic plasticity in metastasis

(2022) Sylvain Delaunay et al.   NATURE

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

(2021) Edward L. Huttlin et al.   CELL

Nucleolar maturation of the human small subunit processome

(2021) Sameer Singh et al.   SCIENCE

p53 induces a survival transcriptional response after nucleolar stress

(2021) Han Liao et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation

(2020) Weili Kong et al.   PLoS Pathogens

Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in Caenorhabditis elegans

(2020) Isabela Cunha Navarro et al.   EMBO JOURNAL

The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

(2020) Clemens Heissenberger et al.   eLife

Eukaryotic 5-methylcytosine (m5C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease

(2019) Katherine Bohnsack et al.   Genes

Uncovering the assembly pathway of human ribosomes and its emerging links to disease

(2019) Katherine E Bohnsack et al.   EMBO JOURNAL

RNA modifications regulating cell fate in cancer

(2019) Sylvain Delaunay et al.   NATURE CELL BIOLOGY

Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation

(2019) Abdulrahim A. Sajini et al.   Nature Communications

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF

(2019) Rainer W. J. Kaiser et al.   Scientific Reports

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program

(2019) Maxime Janin et al.   ACTA NEUROPATHOLOGICA

Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth

(2019) Clemens Heissenberger et al.   NUCLEIC ACIDS RESEARCH

Effect of NOP2 knockdown on colon cancer cell proliferation, migration, and invasion

(2019) Jinling Bi et al.   Translational Cancer Research

OUP accepted manuscript

(2018)   BIOINFORMATICS

RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia

(2018) Jason X. Cheng et al.   Nature Communications

Transient N-6-Methyladenosine Transcriptome Sequencing Reveals a Regulatory Role of m6A in Splicing Efficiency

(2018) Annita Louloupi et al.   Cell Reports

The Role of m6A/m-RNA Methylation in Stress Response Regulation

(2018) Mareen Engel et al.   NEURON

Landscape of the complete RNA chemical modifications in the human 80S ribosome

(2018) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

m6A modification controls the innate immune response to infection by targeting type I interferons

(2018) Roni Winkler et al.   NATURE IMMUNOLOGY

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

(2017) Tom Smith et al.   GENOME RESEARCH

RNA Chemical Proteomics Reveals the N6-Methyladenosine (m6A)-Regulated Protein–RNA Interactome

(2017) A. Emilia Arguello et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualization of chemical modifications in the human 80S ribosome structure

(2017) S. Kundhavai Natchiar et al.   NATURE

Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6

(2017) Ru-Juan Liu et al.   NUCLEIC ACIDS RESEARCH

N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

(2017) Nian Liu et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure

(2016) Zhipeng Lu et al.   CELL

NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNAMet

(2016) Saori Nakano et al.   Nature Chemical Biology

Assembly and trafficking of box C/D and H/ACA snoRNPs

(2016) Séverine Massenet et al.   RNA Biology

UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

(2016) Mirjam Hunziker et al.   Nature Communications

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

(2016) Jean-Louis Langhendries et al.   Oncotarget

NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs

(2015) Sara Haag et al.   RNA

Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120

(2015) Gabrielle Bourgeois et al.   PLoS One

p53 and ribosome biogenesis stress: The essentials

(2014) Lior Golomb et al.   FEBS LETTERS

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

(2014) Eliezer Calo et al.   NATURE

The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21

(2014) Katherine E. Sloan et al.   NUCLEIC ACIDS RESEARCH

Structural and functional studies of Bud23–Trm112 reveal 18S rRNAN7-G1575 methylation occurs on late 40S precursor ribosomes

(2014) Juliette Létoquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA

(2014) K. E. Sloan et al.   RNA

WBSCR22/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N7-methylation of G1639 in human 18S rRNA

(2014) Sara Haag et al.   RNA

NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly

(2014) Metodi Dimitrov Metodiev et al.   PLoS Genetics

Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively

(2013) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

(2013) Shobbir Hussain et al.   Cell Reports

The 5S RNP Couples p53 Homeostasis to Ribosome Biogenesis and Nucleolar Stress

(2013) Katherine E. Sloan et al.   Cell Reports

Mutation in NSUN2, which Encodes an RNA Methyltransferase, Causes Autosomal-Recessive Intellectual Disability

(2012) Muzammil Ahmad Khan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mapping the cleavage sites on mammalian pre-rRNAs: Where do we stand?

(2012) Sahra-Taylor Mullineux et al.   BIOCHIMIE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

The effect of methylation on the hydrogen-bonding and stacking interaction of nucleic acid bases

(2012) Qixia Song et al.   STRUCTURAL CHEMISTRY

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

Single-vector inducible lentiviral RNAi system for oncology target validation

(2011) Dmitri Wiederschain et al.   CELL CYCLE

Eukaryotic 5S rRNA biogenesis

(2011) Martin Ciganda et al.   Wiley Interdisciplinary Reviews-RNA

The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer

(2010) Denis Drygin et al.   Annual Review of Pharmacology and Toxicology

Defects in 18 S or 28 S rRNA Processing Activate the p53 Pathway

(2010) Michael Hölzel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian DEAD Box Protein Ddx51 Acts in 3' End Maturation of 28S rRNA by Promoting the Release of U8 snoRNA

(2010) L. Srivastava et al.   MOLECULAR AND CELLULAR BIOLOGY

Evidence that the AAA+ Proteins TIP48 and TIP49 Bridge Interactions between 15.5K and the Related NOP56 and NOP58 Proteins during Box C/D snoRNP Biogenesis

(2009) K. S. McKeegan et al.   MOLECULAR AND CELLULAR BIOLOGY

Ribosomal Protein S7 Is Both a Regulator and a Substrate of MDM2

(2009) Yan Zhu et al.   MOLECULAR CELL

Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

(2009) Stefano Fumagalli et al.   NATURE CELL BIOLOGY

Bud23 Methylates G1575 of 18S rRNA and Is Required for Efficient Nuclear Export of Pre-40S Subunits

(2008) J. White et al.   MOLECULAR AND CELLULAR BIOLOGY