Mesenchymal stem cell-derived exosomes altered neuron cholesterol metabolism via Wnt5a-LRP1 axis and alleviated cognitive impairment in a progressive Parkinson’s disease model

Cholesterol and Alzheimer’s Disease; From Risk Genes to Pathological Effects

(2021) Femke M. Feringa et al.   Frontiers in Aging Neuroscience

Exosomes isolated during dopaminergic neuron differentiation suppressed neuronal inflammation in a rodent model of Parkinson’s disease

(2021) Yongang Li et al.   NEUROSCIENCE LETTERS

Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged Mice

(2021) Chen Wang et al.   STROKE

Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in aged rats

(2021) Danut-Adrian Dumbrava et al.   GeroScience

LRP1 is a master regulator of tau uptake and spread

(2020) Jennifer N. Rauch et al.   NATURE

Mesenchymal Stromal Cell–Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils

(2020) Chen Wang et al.   STROKE

Mesenchymal stem cell-derived exosome: a promising alternative in the therapy of Alzheimer’s disease

(2020) Mengtian Guo et al.   Alzheimers Research & Therapy

Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

(2020) Sepideh Nikfarjam et al.   Journal of Translational Medicine

The Role of Cholesterol in α‐Synuclein and Lewy Body Pathology in GBA1 Parkinson's Disease

(2020) Patricia García‐Sanz et al.   MOVEMENT DISORDERS

The Role of Lipids in Parkinson’s Disease

(2019) Helena Xicoy et al.   Cells

LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer’s Disease

(2019) Bart Van Gool et al.   MOLECULAR NEUROBIOLOGY

Dysregulated Lipid Metabolism and Its Role in α-Synucleinopathy in Parkinson’s Disease

(2019) Irina Alecu et al.   Frontiers in Neuroscience

Mesenchymal Stem Cells for Regenerative Medicine

(2019) Yu Han et al.   Cells

Ganglioside Metabolism and Parkinson's Disease

(2018) John Forsayeth et al.   Frontiers in Neuroscience

A53T mutant alpha-synuclein induces tau dependent postsynaptic impairment independent of neurodegenerative changes

(2018) Peter J. Teravskis et al.   JOURNAL OF NEUROSCIENCE

The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson’s Disease

(2017) Céline Galvagnion   Journal of Parkinsons Disease

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation

(2016) Zeina El Asmar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Classic and New Animal Models of Parkinson's Disease

(2012) Javier Blesa et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid- 

(2012) T. Kanekiyo et al.   JOURNAL OF NEUROSCIENCE

Lipid Rafts and Alzheimer’s Disease: Protein-Lipid Interactions and Perturbation of Signaling

(2012) David A. Hicks et al.   Frontiers in Physiology

Structure of the Minimal Interface Between ApoE and LRP

(2010) Miklos Guttman et al.   JOURNAL OF MOLECULAR BIOLOGY

LDL Receptor-Related Protein 1 Regulates the Abundance of Diverse Cell-Signaling Proteins in the Plasma Membrane Proteome

(2010) Alban Gaultier et al.   JOURNAL OF PROTEOME RESEARCH

Morris Water Maze Experiment

(2008) Joseph Nunez   Jove-Journal of Visualized Experiments

Mutant α-synuclein exacerbates age-related decrease of neurogenesis

(2007) Beate Winner et al.   NEUROBIOLOGY OF AGING