Pharmacological inhibition of the cGAS-STING signaling pathway suppresses microglial M1-polarization in the spinal cord and attenuates neuropathic pain

STING controls nociception via type I interferon signalling in sensory neurons

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STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

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Role of peripheral and central sensitization in the anti-hyperalgesic effect of hecogenin acetate, an acetylated sapogenin, complexed with β-cyclodextrin: Involvement of NFκB and p38 MAPK pathways

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The Complexity of the cGAS-STING Pathway in CNS Pathologies

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PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway

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cGAS knockdown promotes microglial M2 polarization to alleviate neuroinflammation by inhibiting cGAS-STING signaling pathway in cerebral ischemic stroke

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The cannabinoid system and microglia in health and disease

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Angiotensin II type 1 receptor blockade attenuates posttraumatic stress disorder-related chronic pain by inhibiting glial activation in the spinal cord

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STING/NF-κB/IL-6-Mediated Inflammation in Microglia Contributes to Spared Nerve Injury (SNI)-Induced Pain Initiation

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STING Signaling and Sterile Inflammation

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Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity

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Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage

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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

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Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway

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Perioperative activation of spinal α7 nAChR promotes recovery from preoperative stress-induced prolongation of postsurgical pain

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Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway

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Neuroinflammation and Central Sensitization in Chronic and Widespread Pain

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Cytosolic DNA Sensing Promotes Macrophage Transformation and Governs Myocardial Ischemic Injury

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Parkin and PINK1 mitigate STING-induced inflammation

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Targeting STING with covalent small-molecule inhibitors

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STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis

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Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

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(2013) Andrea Ablasser et al.   NATURE

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

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