The effect of natural polyphenols Resveratrol, Gallic acid, and Kuromanin chloride on human telomerase reverse transcriptase (hTERT) expression in HepG2 hepatocellular carcinoma: role of SIRT1/Nrf2 signaling pathway and oxidative stress

Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

(2022) Ruozhi Dang et al.   Journal of Neuroinflammation

Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway

(2022) Junqiang Zhang et al.   Cells

Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug Resistant Human Leukemia Cells

(2021) Maiara Bernardes Marques et al.   Anti-Cancer Agents in Medicinal Chemistry

Gallic acid attenuates isoniazid and rifampicin-induced liver injury by improving hepatic redox homeostasis through influence on Nrf2 and NF-κB signalling cascades in Wistar Rats

(2021) Sukumaran Sanjay et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Quercetin promotes osteogenic differentiation and antioxidant responses of mouse bone mesenchymal stem cells through activation of the AMPK / SIRT1 signaling pathway

(2021) Nan Wang et al.   PHYTOTHERAPY RESEARCH

Plant Natural Products: Promising Resources for Cancer Chemoprevention

(2021) Li Ma et al.   MOLECULES

Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry-Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells

(2021) Delaram Moghadam et al.   Anti-Cancer Agents in Medicinal Chemistry

Casein Kinase-1-Alpha Inhibitor (D4476) Sensitizes Microsatellite Instable Colorectal Cancer Cells to 5-Fluorouracil via Authophagy Flux Inhibition

(2021) Morvarid Siri et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Role of Phytochemicals in Cancer Chemoprevention: Insights

(2021) Blassan P. George et al.   Antioxidants

Gallic acid attenuates cadmium mediated cardiac hypertrophic remodelling through upregulation of Nrf2 and PECAM-1signalling in rats

(2021) Sasikumar Sundaresan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

A review study on the modulation of SIRT1 expression by miRNAs in aging and age-associated diseases

(2021) Aliabbas Zia et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Nrf2 attenuates ferroptosis-mediated IIR-ALI by modulating TERT and SLC7A11

(2021) Hui Dong et al.   Cell Death & Disease

Nutraceuticals and Cancer: Potential for Natural Polyphenols

(2021) Jessica Maiuolo et al.   Nutrients

The NRF2-dependent transcriptional axis, XRCC5/hTERT drives tumor progression and 5-Fu insensitivity in hepatocellular carcinoma

(2021) Tianze Liu et al.   Molecular Therapy-Oncolytics

TERT—Regulation and Roles in Cancer Formation

(2020) Marta Dratwa et al.   Frontiers in Immunology

Telomeres and telomerase: three decades of progress

(2019) Jerry W. Shay et al.   NATURE REVIEWS GENETICS

Leptin induces SIRT1 expression through activation of NF-E2-related factor 2: Implications for obesity-associated colon carcinogenesis

(2018) Na-Young Song et al.   BIOCHEMICAL PHARMACOLOGY

Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1

(2018) Lei Zhang et al.   Frontiers in Pharmacology

The prognostic significance of hTERT overexpression in cancers

(2018) Kai Wang et al.   MEDICINE

Blackberry Extract Inhibits Telomerase Activity in Human Colorectal Cancer Cells

(2018) Mohsen Tatar et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Gallic acid, a natural polyphenol, protects against tert -butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response

(2017) Rui-Bing Feng et al.   FOOD AND CHEMICAL TOXICOLOGY

Antioxidant ameliorating effects against H2O2-induced cytotoxicity in primary endometrial cells

(2017) F. Zal et al.   TOXICOLOGY MECHANISMS AND METHODS

Antioxidant ameliorating effects against H2O2-induced cytotoxicity in primary endometrial cells

(2017) F. Zal et al.   TOXICOLOGY MECHANISMS AND METHODS

Nrf2/antioxidant defense pathway is involved in the neuroprotective effects of Sirt1 against focal cerebral ischemia in rats after hyperbaric oxygen preconditioning

(2016) Fen Xue et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of blueberry anthocyanins on retinal oxidative stress and inflammation in diabetes through Nrf2/HO-1 signaling

(2016) Yu Song et al.   JOURNAL OF NEUROIMMUNOLOGY

Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma

(2016) F Ahmad et al.   Cell Death & Disease

A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells

(2015) Peixin Huang et al.   Oncotarget

Depletion of Sirtuin 1 (SIRT1) Leads to Epigenetic Modifications of Telomerase (TERT) Gene in Hepatocellular Carcinoma Cells

(2014) Bin Zhang et al.   PLoS One

Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis

(2013) Chatchawan Singhapol et al.   PLoS One

Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells

(2009) Huei-Mei Chen et al.   CANCER LETTERS

Telomerase, mitochondria and oxidative stress

(2009) Gabriele Saretzki   EXPERIMENTAL GERONTOLOGY

Resveratrol protects primary rat hepatocytes against oxidative stress damage:

(2008) Juan Andrés Rubiolo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

(2008) S. Ahmed et al.   JOURNAL OF CELL SCIENCE