In vitro review of nanoparticles attacking macrophages: Interaction and cell death

Toxicity of curcumin nanoparticles towards alveolar macrophage: Effects of surface charges

(2022) Ching-Yee Loo et al.   FOOD AND CHEMICAL TOXICOLOGY

Fetotoxicity of Nanoparticles: Causes and Mechanisms

(2021) Chuanfeng Teng et al.   Nanomaterials

Protein corona mitigated the cytotoxicity of CdTe QDs to macrophages by targeting mitochondria

(2021) Na Liu et al.   NanoImpact

Safe-by-design of Glucan Nanoparticles: the size matters when assessing the immunotoxicity

(2020) Mariana Colaço et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Differences in toxicity, mitochondrial function and miRNome in human cells exposed in vitro to Cd as CdS quantum dots or ionic Cd

(2020) Laura Paesano et al.   JOURNAL OF HAZARDOUS MATERIALS

Neurotoxicity of nanoparticles entering the brain via sensory nerve-to-brain pathways: injuries and mechanisms

(2020) Yuqing Lin et al.   ARCHIVES OF TOXICOLOGY

Nanomedicine: a new paradigm to overcome drug incompatibilities

(2020) Ayat Abdelkader et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Neurotoxicity of metal‐containing nanoparticles and implications in glial cells

(2020) Xiaoru Chang et al.   JOURNAL OF APPLIED TOXICOLOGY

Neutrophils and Macrophages as Targets for Development of Nanotherapeutics in Inflammatory Diseases

(2020) Yujie Su et al.   Pharmaceutics

Iron oxide nanoparticles promote macrophage autophagy and inflammatory response through activation of toll-like Receptor-4 signaling

(2019) Rongrong Jin et al.   BIOMATERIALS

Molecular Responses in THP-1 Macrophage-Like Cells Exposed to Diverse Nanoparticles

(2019) Brzicova et al.   Nanomaterials

Diminished amyloid-β uptake by mouse microglia upon treatment with quantum dots, silver or cerium oxide nanoparticles: Nanoparticles and amyloid-β uptake by microglia

(2019) K Sikorska et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Nanomaterials for Healthcare Biosensing Applications

(2019) Muqsit Pirzada et al.   SENSORS

Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes

(2018) Vahid Mirshafiee et al.   ACS Nano

Titanium dioxide nanoparticle stimulating pro-inflammatory responses in vitro and in vivo for inhibited cancer metastasis

(2018) Fenghui Zhao et al.   LIFE SCIENCES

Gold nanoparticles: Distribution, bioaccumulation and toxicity. In vitro and in vivo studies

(2018) Carlos Lopez-Chaves et al.   Nanomedicine-Nanotechnology Biology and Medicine

Macrophage Recognition of Crystals and Nanoparticles

(2018) Masafumi Nakayama   Frontiers in Immunology

The toxicity of silica nanoparticles to the immune system

(2018) Liangjiao Chen et al.   Nanomedicine

Life, death and autophagy

(2018) Johnna Doherty et al.   NATURE CELL BIOLOGY

Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage

(2018) Lina Xu et al.   Particle and Fibre Toxicology

Zinc oxide nanoparticles impacts: cytotoxicity, genotoxicity, developmental toxicity, and neurotoxicity

(2018) Sanjiv Singh   TOXICOLOGY MECHANISMS AND METHODS

Mechanisms of DNA damage, repair, and mutagenesis

(2017) Nimrat Chatterjee et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

The Toxicity of Nanoparticles Depends on Multiple Molecular and Physicochemical Mechanisms

(2017) Yue-Wern Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of Systematic Variation in Size and Surface Coating of Silver Nanoparticles on Their In Vitro Toxicity to Macrophage RAW 264.7 Cells

(2017) Sunday Makama et al.   TOXICOLOGICAL SCIENCES

Impact of cerium oxide nanoparticles shape on their in vitro cellular toxicity

(2017) Valérie Forest et al.   TOXICOLOGY IN VITRO

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Physico-chemical characteristics, biocompatibility, and MRI applicability of novel monodisperse PEG-modified magnetic Fe3O4&SiO2 core–shell nanoparticles

(2017) Uliana Kostiv et al.   RSC Advances

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation

(2017) Misato Tsugita et al.   Cell Reports

Eu, Gd-Codoped Yttria Nanoprobes for Optical and T1-Weighted Magnetic Resonance Imaging

(2017) Timur Atabaev et al.   Nanomaterials

Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific

(2017) Nobuo Nishijima et al.   Frontiers in Immunology

Differential Protein Adsorption and Cellular Uptake of Silica Nanoparticles Based on Size and Porosity

(2016) Jiban Saikia et al.   ACS Applied Materials & Interfaces

Cytotoxicity and DNA damage in mouse macrophages exposed to silica nanoparticles

(2016) H. Yang et al.   GENETICS AND MOLECULAR RESEARCH

Nanotoxicity: emerging concerns regarding nanomaterial safety and occupational hard metal (WC-Co) nanoparticle exposure

(2016) Andrea L Armstead et al.   International Journal of Nanomedicine

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

(2016) Yi-Nan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

In vitrogenotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment

(2016) Naouale El Yamani et al.   MUTAGENESIS

Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation

(2016) Sergio Arancibia et al.   Nanomedicine

Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice

(2016) Xiaomei Wang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

(2015) Hui-Wen Chiu et al.   Nanoscale

AMP-Conjugated Quantum Dots: Low Immunotoxicity Both In Vitro and In Vivo

(2015) Tongcheng Dai et al.   Nanoscale Research Letters

Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages

(2015) Yiru Qin et al.   TOXICOLOGY

The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice

(2015) Denise Bargheer et al.   Beilstein Journal of Nanotechnology

AMP-Conjugated Quantum Dots: Low Immunotoxicity Both In Vitro and In Vivo

(2015) Tongcheng Dai et al.   Nanoscale Research Letters

Toxic Metals and Autophagy

(2014) Sarmishtha Chatterjee et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Rod-shaped iron oxide nanoparticles are more toxic than sphere-shaped nanoparticles to murine macrophage cells

(2014) Jang Han Lee et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Analysis of cellular responses of macrophages to zinc ions and zinc oxide nanoparticles: a combined targeted and proteomic approach

(2014) Sarah Triboulet et al.   Nanoscale

Physicochemical Properties of Nanomaterials: Implication in Associated Toxic Manifestations

(2014) Manzoor Ahmad Gatoo et al.   Biomed Research International

Nanoparticle clearance is governed by Th1/Th2 immunity and strain background

(2013) Stephen W. Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency

(2013) Anna Lesniak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of Phospholipids in Endocytosis, Phagocytosis, and Macropinocytosis

(2013) Michal Bohdanowicz et al.   PHYSIOLOGICAL REVIEWS

Quantum dots induced monocyte chemotactic protein-1 expression via MyD88-dependent Toll-like receptor signaling pathways in macrophages

(2013) Chia-Chi Ho et al.   TOXICOLOGY

Cytotoxicity and immune response of CdSe/ZnS Quantum dots towards a murine macrophage cell line

(2013) Guimiao Lin et al.   RSC Advances

Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity

(2013) Amruta Manke et al.   Biomed Research International

Cytotoxicity of quantum dots and graphene oxide to erythroid cells and macrophages

(2013) Guangbo Qu et al.   Nanoscale Research Letters

Comprehensive Analysis of the Effects of CdSe Quantum Dot Size, Surface Charge, and Functionalization on Primary Human Lung Cells

(2012) Amber Nagy et al.   ACS Nano

PEGylation of Nanosubstrates (Titania) with Multifunctional Reagents: At the Crossroads between Nanoparticles and Nanocomposites

(2012) Tania Kotsokechagia et al.   LANGMUIR

Cadmium telluride quantum dot nanoparticle cytotoxicity and effects on model immune responses toPseudomonas aeruginosa

(2012) Kathy C Nguyen et al.   Nanotoxicology

Redox active metal-induced oxidative stress in biological systems

(2012) Klaudia Jomova et al.   TRANSITION METAL CHEMISTRY

Phagocytosis and Endocytosis of Silver Nanoparticles Induce Interleukin-8 Production in Human Macrophages

(2012) Seungjae Kim et al.   YONSEI MEDICAL JOURNAL

Impact of Silica Nanoparticle Design on Cellular Toxicity and Hemolytic Activity

(2011) Tian Yu et al.   ACS Nano

Size dependent macrophage responses and toxicological effects of Ag nanoparticles

(2011) Jeongsin Park et al.   CHEMICAL COMMUNICATIONS

Multiwalled Carbon Nanotubes Induce a Fibrogenic Response by Stimulating Reactive Oxygen Species Production, Activating NF-κB Signaling, and Promoting Fibroblast-to-Myofibroblast Transformation

(2011) Xiaoqing He et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The uptake of PLGA micro or nanoparticles by macrophages provokes distinct in vitro inflammatory response

(2011) Roberto Nicolete et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Induction of Inflammasome-dependent Pyroptosis by Carbon Black Nanoparticles

(2011) Anna C. Reisetter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of Nanoparticles on the Immune System

(2011) PremendraD. Dwivedi et al.   Journal of Biomedical Nanotechnology

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of various physicochemical characteristics on the toxicities of ZnO and TiO2 nanoparticles toward human lung epithelial cells

(2011) I-Lun Hsiao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

(2011) Feng Zhao et al.   Small

The uptake and intracellular fate of a series of different surface coated quantum dots in vitro

(2011) Martin J.D. Clift et al.   TOXICOLOGY

Cytotoxic effects and the mechanism of three types of magnetic nanoparticles on human hepatoma BEL-7402 cells

(2011) Wei Kai et al.   Nanoscale Research Letters

Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages

(2011) Hiromi Nabeshi et al.   Nanoscale Research Letters

Nanosized Aluminum Altered Immune Function

(2010) Laura K. Braydich-Stolle et al.   ACS Nano

Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress

(2010) Naqvi et al.   International Journal of Nanomedicine

Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats

(2010) Jane Y. Ma et al.   Nanotoxicology

Cellular uptake and intracellular fate of engineered nanoparticles: A review on the application of imaging techniques

(2010) Ratna Tantra et al.   Nanotoxicology

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

Toxicity of Transition Metal Oxide Nanoparticles: Recent Insights from in vitro Studies

(2010) Yue-Wern Huang et al.   Materials

Potential Health Impact of Nanoparticles

(2009) Tian Xia et al.   Annual Review of Public Health

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Nanoparticles up-regulate tumor necrosis factor-α and CXCL8 via reactive oxygen species and mitogen-activated protein kinase activation

(2009) Hye-Mi Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano