Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons

AAV ablates neurogenesis in the adult murine hippocampus

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Adeno-associated virus (AAV) cell entry: structural insights

(2021) Nancy L. Meyer et al.   TRENDS IN MICROBIOLOGY

Author Correction: Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life

(2020) Gabriel Berdugo-Vega et al.   Nature Communications

Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission

(2020) Jie Zheng et al.   Cell Stem Cell

Dendritic Spines: Mediators of Cognitive Resilience in Aging and Alzheimer’s Disease

(2020) Courtney K. Walker et al.   NEUROSCIENTIST

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients

(2019) Matthew K. Tobin et al.   Cell Stem Cell

Distinct hippocampal engrams control extinction and relapse of fear memory

(2019) Anthony F. Lacagnina et al.   NATURE NEUROSCIENCE

Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus

(2019) Victor M. Luna et al.   SCIENCE

Moving beyond P values: data analysis with estimation graphics

(2019) Joses Ho et al.   NATURE METHODS

Dendritic spines: Revisiting the physiological role

(2019) Saravana Babu Chidambaram et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Adult neurogenesis in mammals

(2019) Fred H. Gage   SCIENCE

Depletion of Caveolin-1 in Type-2 Diabetes Model Induces Alzheimer's disease Pathology Precursors

(2019) Jacqueline A. Bonds et al.   JOURNAL OF NEUROSCIENCE

Functions of adult-born neurons in hippocampal memory interference and indexing

(2019) Samara M. Miller et al.   NATURE NEUROSCIENCE

Probabilistic cell typing enables fine mapping of closely related cell types in situ

(2019) Xiaoyan Qian et al.   NATURE METHODS

Adeno-Associated Viral Vectors in Neuroscience Research

(2019) David L. Haggerty et al.   Molecular Therapy-Methods & Clinical Development

Impaired Hippocampal Neurogenesis and its Enhancement with Ghrelin in 5XFAD Mice

(2018) Minho Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

Early Impairments of Hippocampal Neurogenesis in 5xFAD Mouse Model of Alzheimer’s Disease Are Associated with Altered Expression of SOXB Transcription Factors

(2018) Ivan Zaletel et al.   JOURNAL OF ALZHEIMERS DISEASE

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment

(2018) Éric Samarut et al.   EPILEPSIA

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

(2018) Hongjun Fu et al.   NATURE NEUROSCIENCE

Dentate Gyrus Contributes to Retrieval as well as Encoding: Evidence from Context Fear Conditioning, Recall, and Extinction

(2017) Brian E. Bernier et al.   JOURNAL OF NEUROSCIENCE

Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor

(2017) Sirika Pillay et al.   JOURNAL OF VIROLOGY

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

(2017) Carolyn Hollands et al.   Molecular Neurodegeneration

Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood

(2017) Christoph Anacker et al.   NATURE REVIEWS NEUROSCIENCE

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

(2017) Hongjun Fu et al.   NEURON

Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance

(2017) Fatih Semerci et al.   eLife

Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior

(2016) J. Tiago Gonçalves et al.   CELL

Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity

(2016) Spyridon Chavlis et al.   HIPPOCAMPUS

Reduced pCREB in Alzheimer’s disease prefrontal cortex is reflected in peripheral blood mononuclear cells

(2016) N Bartolotti et al.   MOLECULAR PSYCHIATRY

Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

(2016) Dheeraj S. Roy et al.   NATURE

A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development

(2016) Joseph A. Toonen et al.   PLoS One

Hippocampal neurogenesis: Learning to remember

(2016) Orly Lazarov et al.   PROGRESS IN NEUROBIOLOGY

Transcription-Factor-Dependent Control of Adult Hippocampal Neurogenesis

(2015) Ruth Beckervordersandforth et al.   Cold Spring Harbor Perspectives in Biology

Neurogenesis in the Adult Hippocampus

(2015) Gerd Kempermann et al.   Cold Spring Harbor Perspectives in Biology

A new perspective on the role of the CREB family of transcription factors in memory consolidation via adult hippocampal neurogenesis

(2015) Sylvia Ortega-Martínez   Frontiers in Molecular Neuroscience

Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory

(2015) Jacqueline A. Bonds et al.   PLoS One

Serotype-independent Method of Recombinant Adeno-associated Virus (AAV) Vector Production and Purification

(2015) Koichi Miyake et al.   JOURNAL OF NIPPON MEDICAL SCHOOL

Anisomycin injection in area CA3 of the hippocampus impairs both short-term and long-term memories of contextual fear

(2014) J. Remaud et al.   LEARNING & MEMORY

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

GABAAreceptors can initiate the formation of functional inhibitory GABAergic synapses

(2013) Celine Fuchs et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

(2013) Usman A Khan et al.   NATURE NEUROSCIENCE

Soluble amyloid precursor protein-α rescues age-linked decline in neural progenitor cell proliferation

(2013) Michael P. Demars et al.   NEUROBIOLOGY OF AGING

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Optical controlling reveals time-dependent roles for adult-born dentate granule cells

(2012) Yan Gu et al.   NATURE NEUROSCIENCE

Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain

(2011) A. Gadadhar et al.   JOURNAL OF NEUROSCIENCE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin

(2011) Michael P Demars et al.   Stem Cell Research & Therapy

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

(2010) Michael Demars et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease

(2009) Binggui Sun et al.   Cell Stem Cell

Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

(2009) W. Deng et al.   JOURNAL OF NEUROSCIENCE

GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus

(2009) R. Jagasia et al.   JOURNAL OF NEUROSCIENCE

Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro

(2007) Douglas B. Howard et al.   VIROLOGY