Functions of adult-born neurons in hippocampal memory interference and indexing

Re-evaluating Circuit Mechanisms Underlying Pattern Separation

(2019) N. Alex Cayco-Gajic et al.   NEURON

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Distinct hippocampal engrams control extinction and relapse of fear memory

(2019) Anthony F. Lacagnina et al.   NATURE NEUROSCIENCE

Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus

(2019) Victor M. Luna et al.   SCIENCE

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Preferential Targeting of Lateral Entorhinal Inputs onto Newly Integrated Granule Cells

(2018) Nicholas I. Woods et al.   JOURNAL OF NEUROSCIENCE

Elevation of Hippocampal Neurogenesis Induces a Temporally Graded Pattern of Forgetting of Contextual Fear Memories

(2018) Aijing Gao et al.   JOURNAL OF NEUROSCIENCE

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization

(2018) Nannan Guo et al.   NATURE MEDICINE

Integrating new findings and examining clinical applications of pattern separation

(2018) Stephanie L. Leal et al.   NATURE NEUROSCIENCE

On How the Dentate Gyrus Contributes to Memory Discrimination

(2018) Milenna Tamara van Dijk et al.   NEURON

Dorsal and ventral hippocampal adult-born neurons contribute to context fear memory

(2018) Kylie A. Huckleberry et al.   NEUROPSYCHOPHARMACOLOGY

The hippocampal engram maps experience but not place

(2018) Kazumasa Z. Tanaka et al.   SCIENCE

Egocentric coding of external items in the lateral entorhinal cortex

(2018) Cheng Wang et al.   SCIENCE

Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus

(2018) Claudia Espinoza et al.   Nature Communications

Feedforward inhibition is randomly wired from individual granule cells onto CA3 pyramidal cells

(2017) Máté Neubrandt et al.   HIPPOCAMPUS

Short-Term Facilitation at a Detonator Synapse Requires the Distinct Contribution of Multiple Types of Voltage-Gated Calcium Channels

(2017) Simon Chamberland et al.   JOURNAL OF NEUROSCIENCE

Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood

(2017) Christoph Anacker et al.   NATURE REVIEWS NEUROSCIENCE

In Vivo Imaging of Dentate Gyrus Mossy Cells in Behaving Mice

(2017) Nathan B. Danielson et al.   NEURON

Phase-Locked Inhibition, but Not Excitation, Underlies Hippocampal Ripple Oscillations in Awake Mice In Vivo

(2017) Jian Gan et al.   NEURON

Physiological Properties and Behavioral Correlates of Hippocampal Granule Cells and Mossy Cells

(2017) Yuta Senzai et al.   NEURON

Spatial Representations of Granule Cells and Mossy Cells of the Dentate Gyrus

(2017) Douglas GoodSmith et al.   NEURON

Proximodistal Heterogeneity of Hippocampal CA3 Pyramidal Neuron Intrinsic Properties, Connectivity, and Reactivation during Memory Recall

(2017) Qian Sun et al.   NEURON

Targeting Adult Neurogenesis to Optimize Hippocampal Circuits in Aging

(2017) Kathleen M. McAvoy et al.   Neurotherapeutics

Hippocampal GABAergic Inhibitory Interneurons

(2017) Kenneth A. Pelkey et al.   PHYSIOLOGICAL REVIEWS

Engrams and circuits crucial for systems consolidation of a memory

(2017) Takashi Kitamura et al.   SCIENCE

Extended Interneuronal Network of the Dentate Gyrus

(2017) Gergely G. Szabo et al.   Cell Reports

Silent synapses generate sparse and orthogonal action potential firing in adult-born hippocampal granule cells

(2017) Liyi Li et al.   eLife

Adult-born neurons modify excitatory synaptic transmission to existing neurons

(2017) Elena W Adlaf et al.   eLife

Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity

(2016) Spyridon Chavlis et al.   HIPPOCAMPUS

Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons

(2016) Liam J. Drew et al.   HIPPOCAMPUS

Strong Evidence for Pattern Separation in Human Dentate Gyrus

(2016) D. Berron et al.   JOURNAL OF NEUROSCIENCE

In vivo imaging of dendritic pruning in dentate granule cells

(2016) J Tiago Gonçalves et al.   NATURE NEUROSCIENCE

Bidirectional GABAergic control of action potential firing in newborn hippocampal granule cells

(2016) Stefanie Heigele et al.   NATURE NEUROSCIENCE

Tracking the flow of hippocampal computation: Pattern separation, pattern completion, and attractor dynamics

(2016) James J. Knierim et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Running rewires the neuronal network of adult-born dentate granule cells

(2016) Carmen Vivar et al.   NEUROIMAGE

Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits

(2016) Kathleen M. McAvoy et al.   NEURON

Neuregulin-1/ErbB4 Signaling Regulates Visual Cortical Plasticity

(2016) Yanjun Sun et al.   NEURON

Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding

(2016) Nathan B. Danielson et al.   NEURON

Hippocampal Somatostatin Interneurons Control the Size of Neuronal Memory Ensembles

(2016) Thomas Stefanelli et al.   NEURON

Neuronal Allocation to a Hippocampal Engram

(2016) Sungmo Park et al.   NEUROPSYCHOPHARMACOLOGY

Low excitatory innervation balances high intrinsic excitability of immature dentate neurons

(2016) Cristina V. Dieni et al.   Nature Communications

Young adult born neurons enhance hippocampal dependent performance via influences on bilateral networks

(2016) Jia-Min Zhuo et al.   eLife

Development of Adult-Generated Cell Connectivity with Excitatory and Inhibitory Cell Populations in the Hippocampus

(2015) L. Restivo et al.   JOURNAL OF NEUROSCIENCE

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABA A Receptors Reduces Memory Interference

(2015) Elif Engin et al.   JOURNAL OF NEUROSCIENCE

Experience-Dependent Regulation of Dentate Gyrus Excitability by Adult-Born Granule Cells

(2015) Eun Hye Park et al.   JOURNAL OF NEUROSCIENCE

Neurogliaform cells in cortical circuits

(2015) Linda Overstreet-Wadiche et al.   NATURE REVIEWS NEUROSCIENCE

A Critical Period for Experience-Dependent Remodeling of Adult-Born Neuron Connectivity

(2015) Matteo Bergami et al.   NEURON

Delayed Coupling to Feedback Inhibition during a Critical Period for the Integration of Adult-Born Granule Cells

(2015) Silvio G. Temprana et al.   NEURON

Neural Population Evidence of Functional Heterogeneity along the CA3 Transverse Axis: Pattern Completion versus Pattern Separation

(2015) Heekyung Lee et al.   NEURON

Adult Hippocampal Neurogenesis, Fear Generalization and Stress

(2015) Antoine Besnard et al.   NEUROPSYCHOPHARMACOLOGY

Influence of ontogenetic age on the role of dentate granule neurons

(2014) Sophie Tronel et al.   Brain Structure & Function

Characterization of the role of adult neurogenesis in touch-screen discrimination learning

(2014) Alicia A. Swan et al.   HIPPOCAMPUS

Rapid Dynamic Changes of Dendritic Inhibition in the Dentate Gyrus by Presynaptic Activity Patterns

(2014) Y.-C. Liu et al.   JOURNAL OF NEUROSCIENCE

Genetic Activation of ERK5 MAP Kinase Enhances Adult Neurogenesis and Extends Hippocampus-Dependent Long-Term Memory

(2014) W. Wang et al.   JOURNAL OF NEUROSCIENCE

Ezh2 Regulates Adult Hippocampal Neurogenesis and Memory

(2014) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Functional organization of the hippocampal longitudinal axis

(2014) Bryan A. Strange et al.   NATURE REVIEWS NEUROSCIENCE

CA3 Retrieves Coherent Representations from Degraded Input: Direct Evidence for CA3 Pattern Completion and Dentate Gyrus Pattern Separation

(2014) Joshua P. Neunuebel et al.   NEURON

Cortical Representations Are Reinstated by the Hippocampus during Memory Retrieval

(2014) Kazumasa Z. Tanaka et al.   NEURON

Hippocampal Memory Traces Are Differentially Modulated by Experience, Time, and Adult Neurogenesis

(2014) Christine A. Denny et al.   NEURON

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

Temporally selective contextual encoding in the dentate gyrus of the hippocampus

(2014) L.M. Rangel et al.   Nature Communications

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

GABA Depolarization Is Required for Experience-Dependent Synapse Unsilencing in Adult-Born Neurons

(2013) J. H. Chancey et al.   JOURNAL OF NEUROSCIENCE

Distinct Determinants of Sparse Activation during Granule Cell Maturation

(2013) C. V. Dieni et al.   JOURNAL OF NEUROSCIENCE

Seamless Reconstruction of Intact Adult-Born Neurons by Serial End-Block Imaging Reveals Complex Axonal Guidance and Development in the Adult Hippocampus

(2013) G. J. Sun et al.   JOURNAL OF NEUROSCIENCE

The Sparseness of Mixed Selectivity Neurons Controls the Generalization-Discrimination Trade-Off

(2013) O. Barak et al.   JOURNAL OF NEUROSCIENCE

Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb

(2013) A. Deshpande et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hilar mossy cells of the dentate gyrus: a historical perspective

(2013) Helen E. Scharfman et al.   Frontiers in Neural Circuits

Adult neurogenesis modifies excitability of the dentate gyrus

(2013) Taruna Ikrar et al.   Frontiers in Neural Circuits

Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice

(2013) Wei Deng et al.   eLife

Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion

(2012) Toshiaki Nakashiba et al.   CELL

A fight for survival: The challenges faced by a newborn neuron integrating in the adult hippocampus

(2012) Matteo Bergami et al.   Developmental Neurobiology

Adult-born hippocampal neurons promote cognitive flexibility in mice

(2012) Nesha S. Burghardt et al.   HIPPOCAMPUS

NR2B-Dependent Plasticity of Adult-Born Granule Cells is Necessary for Context Discrimination

(2012) M. A. Kheirbek et al.   JOURNAL OF NEUROSCIENCE

Spatial Firing Correlates of Physiologically Distinct Cell Types of the Rat Dentate Gyrus

(2012) J. P. Neunuebel et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Adult Neurogenesis by Inducible and Targeted Deletion of ERK5 Mitogen-Activated Protein Kinase Specifically in Adult Neurogenic Regions Impairs Contextual Fear Extinction and Remote Fear Memory

(2012) Y.-W. Pan et al.   JOURNAL OF NEUROSCIENCE

Long-Lasting Plasticity of Hippocampal Adult-Born Neurons

(2012) V. Lemaire et al.   JOURNAL OF NEUROSCIENCE

Optogenetic stimulation of a hippocampal engram activates fear memory recall

(2012) Xu Liu et al.   NATURE

Optical controlling reveals time-dependent roles for adult-born dentate granule cells

(2012) Yan Gu et al.   NATURE NEUROSCIENCE

Hilar Mossy Cell Degeneration Causes Transient Dentate Granule Cell Hyperexcitability and Impaired Pattern Separation

(2012) Seiichiro Jinde et al.   NEURON

Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network

(2012) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons

(2012) Antonia Marín-Burgin et al.   SCIENCE

Competition from newborn granule cells does not drive axonal retraction of silenced old granule cells in the adult hippocampus

(2012) Carla M. Lopez et al.   Frontiers in Neural Circuits

Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region

(2012) Yosuke Niibori et al.   Nature Communications

Monosynaptic inputs to new neurons in the dentate gyrus

(2012) Carmen Vivar et al.   Nature Communications

Posttraining Ablation of Adult-Generated Neurons Degrades Previously Acquired Memories

(2011) M. Arruda-Carvalho et al.   JOURNAL OF NEUROSCIENCE

Learning-related feedforward inhibitory connectivity growth required for memory precision

(2011) Sarah Ruediger et al.   NATURE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Resolving New Memories: A Critical Look at the Dentate Gyrus, Adult Neurogenesis, and Pattern Separation

(2011) James B. Aimone et al.   NEURON

Pattern Separation: A Common Function for New Neurons in Hippocampus and Olfactory Bulb

(2011) Amar Sahay et al.   NEURON

Compensatory network changes in the dentate gyrus restore long-term potentiation following ablation of neurogenesis in young-adult mice

(2011) B. H. Singer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months

(2011) S. J. Kohler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional convergence of developmentally and adult-generated granule cells in dentate gyrus circuits supporting hippocampus-dependent memory

(2010) Scellig S.D. Stone et al.   HIPPOCAMPUS

Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus

(2010) Clay O. Lacefield et al.   HIPPOCAMPUS

Adult-born neurons are necessary for extended contextual discrimination

(2010) Sophie Tronel et al.   HIPPOCAMPUS

Frequency-Tuned Distribution of Inhibition in the Dentate Gyrus

(2010) L. A. Ewell et al.   JOURNAL OF NEUROSCIENCE

Role of microcircuit structure and input integration in hippocampal interneuron recruitment and plasticity

(2010) Marlene Bartos et al.   NEUROPHARMACOLOGY

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years

(2010) Rolf Knoth et al.   PLoS One

Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory

(2009) Takashi Kitamura et al.   CELL

Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

(2009) W. Deng et al.   JOURNAL OF NEUROSCIENCE

GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus

(2009) R. Jagasia et al.   JOURNAL OF NEUROSCIENCE

Adult-Born Hippocampal Neurons Are More Numerous, Faster Maturing, and More Involved in Behavior in Rats than in Mice

(2009) J. S. Snyder et al.   JOURNAL OF NEUROSCIENCE

The Input-Output Transformation of the Hippocampal Granule Cells: From Grid Cells to Place Fields

(2009) L. de Almeida et al.   JOURNAL OF NEUROSCIENCE

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

(2009) Alexander Garthe et al.   PLoS One

Reliable Activation of Immature Neurons in the Adult Hippocampus

(2009) Lucas A. Mongiat et al.   PLoS One

Feed-forward inhibition as a buffer of the neuronal input-output relation

(2009) M. Ferrante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

The effects of running and of inhibiting adult neurogenesis on learning and memory in rats

(2008) J. Martin Wojtowicz et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A role for hilar cells in pattern separation in the dentate gyrus: A computational approach

(2008) Catherine E. Myers et al.   HIPPOCAMPUS

Neurons born in the adult dentate gyrus form functional synapses with target cells

(2008) Nicolas Toni et al.   NATURE NEUROSCIENCE

Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

(2008) R. L. Faulkner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pattern Separation in the Human Hippocampal CA3 and Dentate Gyrus

(2008) A. Bakker et al.   SCIENCE