Progranulin Controls Sepsis via C/EBPα-RegulatedIl10Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Progranulin Controls Sepsis via C/EBPα-RegulatedIl10Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation
Authors
Keywords
-
Journal
JOURNAL OF IMMUNOLOGY
Volume 197, Issue 8, Pages 3393-3405
Publisher
The American Association of Immunologists
Online
2016-09-13
DOI
10.4049/jimmunol.1600862
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock
- (2016) Yuan Yu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- C/EBPα regulates macrophage activation and systemic metabolism
- (2014) Bonggi Lee et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Interleukin (IL)-32β-mediated CCAAT/Enhancer-binding Protein α (C/EBPα) Phosphorylation by Protein Kinase Cδ (PKCδ) Abrogates the Inhibitory Effect of C/EBPα on IL-10 Production
- (2013) Jeong-Woo Kang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- E3 Ubiquitin Ligase E6AP Negatively Regulates Adipogenesis by Downregulating Proadipogenic Factor C/EBPalpha
- (2013) Pooja Pal et al. PLoS One
- E6AP, an E3 ubiquitin ligase negatively regulates granulopoiesis by targeting transcription factor C/EBPα for ubiquitin-mediated proteasome degradation
- (2013) P Pal et al. Cell Death & Disease
- Insights into the role of progranulin in immunity, infection, and inflammation
- (2012) J. Jian et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Prevention of LPS-Induced Acute Lung Injury in Mice by Progranulin
- (2012) Zhongliang Guo et al. MEDIATORS OF INFLAMMATION
- Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice
- (2012) Y. Tanaka et al. NEUROSCIENCE
- Neuroprotective effects of progranulin in ischemic mice
- (2011) Jiang Tao et al. BRAIN RESEARCH
- Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling
- (2011) Boyoun Park et al. IMMUNITY
- HDL/Apolipoprotein A-I Binds to Macrophage-Derived Progranulin and Suppresses its Conversion into Proinflammatory Granulins
- (2011) Hanayuki Okura et al. Journal of Atherosclerosis and Thrombosis
- Mal Mediates TLR-Induced Activation of CREB and Expression of IL-10
- (2011) M. Mellett et al. JOURNAL OF IMMUNOLOGY
- Cellular Effects of Progranulin in Health and Disease
- (2011) Louis De Muynck et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Synaptic dysfunction in progranulin-deficient mice
- (2011) Terri L. Petkau et al. NEUROBIOLOGY OF DISEASE
- Progranulin, a Glycoprotein Deficient in Frontotemporal Dementia, Is a Novel Substrate of Several Protein Disulfide Isomerase Family Proteins
- (2011) Sandra Almeida et al. PLoS One
- The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice
- (2011) W. Tang et al. SCIENCE
- Nonresolving Inflammation
- (2010) Carl Nathan et al. CELL
- Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis
- (2010) Jian Q. Feng et al. FASEB JOURNAL
- Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia
- (2010) Fangfang Yin et al. FASEB JOURNAL
- Triptolide Inhibits IL-12/IL-23 Expression in APCs via CCAAT/Enhancer-Binding Protein
- (2010) Y. Zhang et al. JOURNAL OF IMMUNOLOGY
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
- (2010) Vivianna M Van Deerlin et al. NATURE GENETICS
- Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin
- (2010) Fenghua Hu et al. NEURON
- The granulin gene family: from cancer to dementia
- (2009) Andrew Bateman et al. BIOESSAYS
- Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
- (2009) Fangfang Yin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Immunodesign of experimental sepsis by cecal ligation and puncture
- (2009) Daniel Rittirsch et al. Nature Protocols
- Protein Kinase Cδ Stimulates Proteasome-Dependent Degradation of C/EBPα during Apoptosis Induction of Leukemic Cells
- (2009) Meng Zhao et al. PLoS One
- C/EBPα S248A mutation reduces granulocytic differentiation in human leukemic K562 cells
- (2008) Sheo M. Singh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started