Direct visualization of living bacterial genotypes using CRISPR/Cas12a-circular reporter nanoprobes

PAM-less conditional DNA substrates leverage trans-cleavage of CRISPR-Cas12a for versatile live-cell biosensing

(2022) Siyu Chen et al.   Chemical Science

Quantitative Fluorescence In Situ Hybridization (FISH) of Magnetically Confined Bacteria Enables Early Detection of Human Bacteremia

(2022) Min Seok Lee et al.   Small Methods

Enzyme‐Activated, Chemiluminescent Siderophore‐Dioxetane Probes Enable the Selective and Highly Sensitive Detection of Bacterial Pathogens

(2022) Carsten Peukert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A polyphenol-assisted IL-10 mRNA delivery system for ulcerative colitis

(2022) Zhejie Chen et al.   Acta Pharmaceutica Sinica B

Hollow covalent organic framework-sheltering CRISPR/Cas12a as an in-vivo nanosensor for ATP imaging

(2022) Yongchun Pan et al.   BIOSENSORS & BIOELECTRONICS

Imaging Commensal Microbiota and Pathogenic Bacteria in the Gut

(2021) Liyuan Lin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cyanine‐Dyad Molecular Probe for the Simultaneous Profiling of the Evolution of Multiple Radical Species During Bacterial Infections

(2021) Zhimin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adjuvant-like biomimetic nanovesicles combat New Delhi metallo-β-lactamases (NDMs) producing superbugs infections

(2021) SiXuan Wu et al.   Nano Today

Cells of the human intestinal tract mapped across space and time

(2021) Rasa Elmentaite et al.   NATURE

The architecture of the Gram-positive bacterial cell wall

(2020) L. Pasquina-Lemonche et al.   NATURE

CRISPR Mediated Biosensing Toward Understanding Cellular Biology and Point‐of‐Care Diagnosis

(2020) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly multiplexed spatial mapping of microbial communities

(2020) Hao Shi et al.   NATURE

Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

(2019) Benjamin P. Kleinstiver et al.   NATURE BIOTECHNOLOGY

Development of a Universal Fluorescent Probe for Gram-Positive Bacteria

(2019) Haw-Young Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifunctional nanoagents for ultrasensitive imaging and photoactive killing of Gram-negative and Gram-positive bacteria

(2019) Jiali Tang et al.   Nature Communications

Mechanically resolved imaging of bacteria using expansion microscopy

(2019) Youngbin Lim et al.   PLOS BIOLOGY

Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies

(2018) Spencer C. Knight et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Detecting RNA base methylations in single cells by in situ hybridization

(2018) Rohan T. Ranasinghe et al.   Nature Communications

A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of life

(2018) Donovan H Parks et al.   NATURE BIOTECHNOLOGY

Spatial organization of a model 15-member human gut microbiota established in gnotobiotic mice

(2017) Jessica L. Mark Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive detection and identification of bacterial DNA in the blood of patients with sepsis and healthy volunteers using next-generation sequencing method - the observation of DNAemia

(2016) T. Gosiewski et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Quantitative Imaging of Gut Microbiota Spatial Organization

(2015) Kristen A. Earle et al.   Cell Host & Microbe

probeBase—an online resource for rRNA-targeted oligonucleotide probes and primers: new features 2016

(2015) Daniel Greuter et al.   NUCLEIC ACIDS RESEARCH

Systems-level analysis of microbial community organization through combinatorial labeling and spectral imaging

(2011) A. M. Valm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Bacteria Using Glyco-Dendronized Polylysine Prepared by Continuous Flow Photofunctionalization

(2010) Paola Laurino et al.   NANO LETTERS

Resistance Plasmid Families in Enterobacteriaceae

(2009) A. Carattoli   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY