Amyloid aggregates exert cell toxicity causing irreversible damages in the endoplasmic reticulum

A unifying framework for amyloid-mediated membrane damage: The lipid-chaperone hypothesis

(2022) Carmelo Tempra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Nanoscale Structural Analysis of a Lipid-Driven Aggregation of Insulin

(2022) Stanislav Rizevsky et al.   Journal of Physical Chemistry Letters

Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes

(2021) Danilo Milardi et al.   CHEMICAL REVIEWS

A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

(2021) Rodrigo Cataldi et al.   Communications Biology

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

(2021) Marie P. Schützmann et al.   Nature Communications

Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease

(2021) Sandra Villegas et al.   Neural Regeneration Research

Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway

(2020) Karen E. Marshall et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nanoscale Structural Characterization of Individual Viral Particles Using Atomic Force Microscopy Infrared Spectroscopy (AFM-IR) and Tip-Enhanced Raman Spectroscopy (TERS)

(2020) Tianyi Dou et al.   ANALYTICAL CHEMISTRY

Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy

(2020) Francesco Simone Ruggeri et al.   Nature Communications

Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome

(2020) Dirk Fitzner et al.   Cell Reports

Nanometre-scale spectroscopic visualization of catalytic sites during a hydrogenation reaction on a Pd/Au bimetallic catalyst

(2020) Hao Yin et al.   Nature Catalysis

Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins

(2020) Michele F. Sciacca et al.   ACS Chemical Neuroscience

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor

(2019) Megan C. Kopp et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes

(2018) Federica Scollo et al.   Journal of Physical Chemistry Letters

A new era for understanding amyloid structures and disease

(2018) Matthew G. Iadanza et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Huntington's disease: a clinical review

(2017) P. McColgan et al.   EUROPEAN JOURNAL OF NEUROLOGY

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β

(2017) Kyle J. Korshavn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

AFM-IR: Technology and Applications in Nanoscale Infrared Spectroscopy and Chemical Imaging

(2016) Alexandre Dazzi et al.   CHEMICAL REVIEWS

Lipid-assisted protein transport: A diffusion-reaction model supported by kinetic experiments and molecular dynamics simulations

(2016) Carmelo La Rosa et al.   JOURNAL OF CHEMICAL PHYSICS

Exploring the structure and formation mechanism of amyloid fibrils by Raman spectroscopy: a review

(2015) Dmitry Kurouski et al.   ANALYST

Absorption Spectroscopy and Imaging from the Visible through Mid-Infrared with 20 nm Resolution

(2015) Aaron M. Katzenmeyer et al.   ANALYTICAL CHEMISTRY

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

(2015) Céline Galvagnion et al.   Nature Chemical Biology

Tip-enhanced infrared nanospectroscopy via molecular expansion force detection

(2014) Feng Lu et al.   Nature Photonics

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nanoscale Infrared Spectroscopy: Improving the Spectral Range of the Photothermal Induced Resonance Technique

(2013) Aaron M. Katzenmeyer et al.   ANALYTICAL CHEMISTRY

Pathogenic Serum Amyloid A 1.1 Shows a Long Oligomer-rich Fibrillation Lag Phase Contrary to the Highly Amyloidogenic Non-pathogenic SAA2.2

(2012) Saipraveen Srinivasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Composition of Insulin Fibril Surfaces Probed by TERS

(2012) Dmitry Kurouski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system

(2012) Lin Zheng et al.   Translational Neurodegeneration

Spontaneous inter-conversion of insulin fibril chirality

(2011) Dmitry Kurouski et al.   CHEMICAL COMMUNICATIONS

The binary switch that controls the life and death decisions of ER stressed β cells

(2010) Christine M Oslowski et al.   CURRENT OPINION IN CELL BIOLOGY

Theory of infrared nanospectroscopy by photothermal induced resonance

(2010) A. Dazzi et al.   JOURNAL OF APPLIED PHYSICS

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

(2010) Sonya G. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION

Seeded growth of  -amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

(2009) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update of the LIPID MAPS comprehensive classification system for lipids

(2008) Eoin Fahy et al.   JOURNAL OF LIPID RESEARCH

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY