Exploring Quercetin Anti-Osteoporosis Pharmacological Mechanisms with In Silico and In Vivo Models

Reveals of quercetin’s therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation

(2022) Zhibai Zhao et al.   Scientific Reports

Cyanidin-3-glucoside Regulates Osteoblast Differentiation via the ERK1/2 Signaling Pathway

(2021) Bosen Hu et al.   ACS Omega

Systemic NF-κB-mediated inflammation promotes an aging phenotype in skeletal stem/progenitor cells

(2021) Anne Marie Josephson et al.   Aging-US

Investigating the Mechanism of Scutellariae barbata Herba in the Treatment of Colorectal Cancer by Network Pharmacology and Molecular Docking

(2021) Xiangjun Qi et al.   Evidence-based Complementary and Alternative Medicine

Network Pharmacology-Based Investigation on the Anti-Osteoporosis Mechanism of Astragaloside IV

(2021) Li Ou et al.   Natural Product Communications

Analysis of Molecular Mechanism of Erxian Decoction in Treating Osteoporosis Based on Formula Optimization Model

(2021) Lang Yang et al.   Oxidative Medicine and Cellular Longevity

Artemisinin Reverses Glucocorticoid-Induced Injury in Bone Marrow-Derived Mesenchymal Stem Cells through Regulation of ERK1/2-CREB Signaling Pathway

(2021) Jiankang Fang et al.   Oxidative Medicine and Cellular Longevity

Potential modulatory mechanisms of action by long-chain polyunsaturated fatty acids on bone cell and chondrocyte metabolism

(2021) Maryam Abshirini et al.   PROGRESS IN LIPID RESEARCH

Use of Network Pharmacology and Molecular Docking Technology to Analyze the Mechanism of Action of Velvet Antler in the Treatment of Postmenopausal Osteoporosis

(2021) Kuiting Guo et al.   Evidence-based Complementary and Alternative Medicine

Animal Model for Glucocorticoid Induced Osteoporosis: A Systematic Review from 2011 to 2021

(2021) Andy Xavier et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic target database update 2022: facilitating drug discovery with enriched comparative data of targeted agents

(2021) Ying Zhou et al.   NUCLEIC ACIDS RESEARCH

A network pharmacology approach to explore the potential targets underlying the effect of sinomenine on rheumatoid arthritis

(2020) Xiang Guo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Uncovering the Pharmacological Mechanism of Stemazole in the Treatment of Neurodegenerative Diseases Based on a Network Pharmacology Approach

(2020) Jing Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Baicalin Ameliorates Dexamethasone-Induced Osteoporosis by Regulation of the RANK/RANKL/OPG Signaling Pathway

(2020) Ye Zhao et al.   Drug Design Development and Therapy

Exploring the mechanism of action Xianlingubao Prescription in the treatment of osteoporosis by network pharmacology

(2020) Naiqiang Zhu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Evaluation of genetic variants in IL‐1B and its interaction with the predisposition of osteoporosis in the northwestern Chinese Han population

(2020) Zhiyi He et al.   JOURNAL OF GENE MEDICINE

Quercetin as an Agent for Protecting the Bone: A Review of the Current Evidence

(2020) Sok Kuan Wong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Network Pharmacology Analysis to Uncover the Potential Mechanisms of Lycium barbarum on Colorectal Cancer

(2020) Yi Lu et al.   Interdisciplinary Sciences-Computational Life Sciences

Molecular Mechanism of the Effect of Huanglian Jiedu Decoction on Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking

(2020) Bei Yin et al.   Journal of Diabetes Research

Exosomes as a Novel Approach to Reverse Osteoporosis: A Review of the Literature

(2020) Xudong Xie et al.   Frontiers in Bioengineering and Biotechnology

Zebrafish as an Emerging Model for Osteoporosis: A Primary Testing Platform for Screening New Osteo-Active Compounds

(2019) Dylan J. M. Bergen et al.   Frontiers in Endocrinology

The epidemiology of osteoporosis, associated fragility fractures, and management gap in China

(2019) Fan Yu et al.   Archives of Osteoporosis

Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment

(2019) Runzhi Zhang et al.   Frontiers in Pharmacology

Toxic effects of oxine-copper on development and behavior in the embryo-larval stages of zebrafish

(2019) Honglei Wang et al.   AQUATIC TOXICOLOGY

The DisGeNET knowledge platform for disease genomics: 2019 update

(2019) Janet Piñero et al.   NUCLEIC ACIDS RESEARCH

The role of IL-1B in breast cancer bone metastasis

(2018) Claudia Tulotta et al.   ENDOCRINE-RELATED CANCER

Computational modeling of human oral bioavailability: what will be next?

(2018) Miguel Ángel Cabrera-Pérez et al.   Expert Opinion on Drug Discovery

A large lung gene expression study identifying IL1B as a novel player in airway inflammation in COPD airway epithelial cells

(2018) Gao Yi et al.   INFLAMMATION RESEARCH

3′-UTR Polymorphisms of MTHFR and TS Associated with Osteoporotic Vertebral Compression Fracture Susceptibility in Postmenopausal Women

(2018) Tae-Keun Ahn et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers

(2018) Arjun Patra et al.   International Journal of Nanomedicine

A global transcriptional network connecting noncoding mutations to changes in tumor gene expression

(2018) Wei Zhang et al.   NATURE GENETICS

Antioxidant and anti-inflammatory activities of quercetin and its derivatives

(2018) Marija Lesjak et al.   Journal of Functional Foods

TNF and Bone Remodeling

(2017) Baohong Zhao   Current Osteoporosis Reports

Genetic association study identified a 20 kb regulatory element in WLS associated with osteoporosis and bone mineral density in Han Chinese

(2017) Dangfeng Zhang et al.   Scientific Reports

CytoNCA: A cytoscape plugin for centrality analysis and evaluation of protein interaction networks

(2015) Yu Tang et al.   BIOSYSTEMS

Projection of osteoporosis-related fractures and costs in China: 2010–2050

(2015) L. Si et al.   OSTEOPOROSIS INTERNATIONAL

Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells

(2015) Rinaldo Florencio-Silva et al.   Biomed Research International

Disruption of NF-κB1 prevents bone loss caused by mechanical unloading

(2013) Hitomi Nakamura et al.   JOURNAL OF BONE AND MINERAL RESEARCH

DoGSiteScorer: a web server for automatic binding site prediction, analysis and druggability assessment

(2012) A. Volkamer et al.   BIOINFORMATICS

In SilicoSyndrome Prediction for Coronary Artery Disease in Traditional Chinese Medicine

(2012) Peng Lu et al.   Evidence-based Complementary and Alternative Medicine

c-Jun/AP-1 transcription factor regulates laminin-1-induced neurite outgrowth in human bone marrow mesenchymal stem cells: Role of multiple signaling pathways

(2011) S. Mruthyunjaya et al.   FEBS LETTERS

A 1HNMR-Based Metabonomics Study of Postmenopausal Osteoporosis and Intervention Effects of Er-Xian Decoction in Ovariectomized Rats

(2011) Liming Xue et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Timing of Decompressive Surgery of Spinal Cord after Traumatic Spinal Cord Injury: An Evidence-Based Examination of Pre-Clinical and Clinical Studies

(2009) Julio C. Furlan et al.   JOURNAL OF NEUROTRAUMA

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice

(2008) Sergio Vaira et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of quercetin on bone formation

(2008) Ricky W.K. Wong et al.   JOURNAL OF ORTHOPAEDIC RESEARCH