TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt

Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension

(2021) Rhéure Alves-Lopes et al.   HYPERTENSION

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival

(2019) Lorenz Mittermeier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Functional Analysis of Selenium-Related Genes and Magnesium-Related Genes in the Gene Expression Profile Microarray in the Peripheral Blood Mononuclear Cells of Keshan Disease

(2019) Sen Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis

(2019) Francisco J Rios et al.   CARDIOVASCULAR RESEARCH

Primary Aldosteronism

(2019) John W. Funder   HYPERTENSION

Clinical significance of serum magnesium levels in patients with heart failure with preserved ejection fraction

(2019) Taiki Nishihara et al.   MEDICINE

Protein phosphatase magnesium-dependent 1A induces inflammation in rheumatoid arthritis

(2019) Beomgu Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein phosphatase Mg 2+ /Mn 2+ dependent‐1A and PTEN deregulation in renal fibrosis: Novel mechanisms and co‐dependency of expression

(2019) Jiaqi Tang et al.   FASEB JOURNAL

Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness

(2018) Guanghong Jia et al.   HYPERTENSION

Role of kinase-coupled TRP channels in mineral homeostasis

(2018) Vladimir Chubanov et al.   PHARMACOLOGY & THERAPEUTICS

Mineralocorticoid Receptor and Cardiovascular Disease

(2018) Mathieu Buonafine et al.   AMERICAN JOURNAL OF HYPERTENSION

TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut

(2017) Andrea Romagnani et al.   Nature Communications

Transient Receptor Potential Melastatin 7 Cation Channel KinaseNovelty and Significance

(2016) Tayze T. Antunes et al.   HYPERTENSION

Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg2+ homeostasis and cytoskeletal architecture

(2016) Simon Stritt et al.   Nature Communications

NADPH Oxidase 4 Induces Cardiac Fibrosis and Hypertrophy Through Activating Akt/mTOR and NF B Signaling Pathways

(2015) Q. D. Zhao et al.   CIRCULATION

Results from the Atherosclerosis Risk in Communities study suggest that low serum magnesium is associated with incident kidney disease

(2015) Adrienne Tin et al.   KIDNEY INTERNATIONAL

Mg2+ homeostasis

(2014) Jenny van der Wijst et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Inactivation of TRPM7 kinase activity does not impair its channel function in mice

(2014) Taku Kaitsuka et al.   Scientific Reports

CNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia

(2014) Francisco J. Arjona et al.   PLoS Genetics

Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domain

(2013) Alvaro Yogi et al.   CELLULAR SIGNALLING

Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease

(2013) Andreas Tomaschitz et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Contribution of aldosterone to cardiovascular and renal inflammation and fibrosis

(2013) Nancy J. Brown   Nature Reviews Nephrology

Cleavage of TRPM7 Releases the Kinase Domain from the Ion Channel and Regulates Its Participation in Fas-Induced Apoptosis

(2012) Bimal N. Desai et al.   DEVELOPMENTAL CELL

Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake

(2012) A D Rao et al.   JOURNAL OF HUMAN HYPERTENSION

Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia

(2011) Alvaro Yogi et al.   JOURNAL OF HYPERTENSION

Transient Receptor Potential Melastatin 7 (TRPM7) Cation Channels, Magnesium and the Vascular System in Hypertension

(2010) Alvaro Yogi et al.   CIRCULATION JOURNAL

TRPM7 is essential for Mg2+ homeostasis in mammals

(2010) Lillia V. Ryazanova et al.   Nature Communications

Downregulation of Renal TRPM7 and Increased Inflammation and Fibrosis in Aldosterone-Infused Mice

(2008) Bruno Sontia et al.   HYPERTENSION

Regulation of the novel Mg2+ transporter transient receptor potential melastatin 7 (TRPM7) cation channel by bradykinin in vascular smooth muscle cells

(2008) Glaucia E Callera et al.   JOURNAL OF HYPERTENSION