Pro-α-cell-derived β-cells contribute to β-cell neogenesis induced by antagonistic glucagon receptor antibody in type 2 diabetic mice

Pancreatic β cell regeneration induced by clinical and preclinical agents

(2021) Kang-Li Wang et al.   World Journal of Stem Cells

Glucagon receptor antagonist upregulates circulating GLP-1 level by promoting intestinal L-cell proliferation and GLP-1 production in type 2 diabetes

(2020) Shan Lang et al.   BMJ Open Diabetes Research & Care

Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche

(2020) Mirza Muhammad Fahd Qadir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study

(2020) Yongze Li et al.   BMJ-British Medical Journal

Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy

(2020) Gopika G. Nair et al.   Nature Reviews Endocrinology

Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice

(2020) Rui Wei et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Glucagon receptor antagonism promotes the production of gut proglucagon-derived peptides in diabetic mice

(2020) Shan Lang et al.   PEPTIDES

Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells

(2019) Kenichiro Furuyama et al.   NATURE

Artemether Does Not Turn α Cells into β Cells

(2018) Talitha van der Meulen et al.   Cell Metabolism

Effect of a glucagon receptor antibody (REMD-477) in type 1 diabetes: A randomized controlled trial

(2018) Jeremy Pettus et al.   DIABETES OBESITY & METABOLISM

Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice

(2018) Ankit X. Sharma et al.   Cell Reports

Stem cells in the treatment of diabetes mellitus — Focus on mesenchymal stem cells

(2018) Günter Päth et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The New Biology and Pharmacology of Glucagon

(2017) T. D. Müller et al.   PHYSIOLOGICAL REVIEWS

Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice

(2017) Haruka Okamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lineage Reprogramming: A Promising Road for Pancreatic β Cell Regeneration

(2016) Rui Wei et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

GLP-1 Analog Liraglutide Enhances Proinsulin Processing in Pancreatic β-Cells via a PKA-Dependent Pathway

(2014) Liang Wang et al.   ENDOCRINOLOGY

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

(2014) Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action

(2013) Jonathan E. Campbell et al.   Cell Metabolism

Adult Duct-Lining Cells Can Reprogram into β-like Cells Able to Counter Repeated Cycles of Toxin-Induced Diabetes

(2013) Keith Al-Hasani et al.   DEVELOPMENTAL CELL

Incretin Action in the Pancreas: Potential Promise, Possible Perils, and Pathological Pitfalls

(2013) D. J. Drucker   DIABETES

Predominance of β-Cell Neogenesis Rather Than Replication in Humans With an Impaired Glucose Tolerance and Newly Diagnosed Diabetes

(2013) S. Yoneda et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells

(2013) Monica Courtney et al.   PLoS Genetics

Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

(2011) Y. Lee et al.   DIABETES

Novel insight into glucagon receptor action: lessons from knockout and transgenic mouse models

(2011) P. M. Vuguin et al.   DIABETES OBESITY & METABOLISM

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

(2009) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transdifferentiation of pancreatic ductal cells to endocrine β-cells

(2008) Susan Bonner-Weir et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

Novel Effectors of Directed and Ngn3-Mediated Differentiation of Mouse Embryonic Stem Cells into Endocrine Pancreas Progenitors

(2007) Ioannis Serafimidis et al.   STEM CELLS