Beneficial Effects of lncRNA-UC.360+ shRNA on Diabetic Cardiac Sympathetic Damage via NLRP3 Inflammasome-Induced Pyroptosis in Stellate Ganglion

Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis

(2022) Yan Jiao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Paeoniflorin Upregulates Mitochondrial Thioredoxin of Schwann Cells to Improve Diabetic Peripheral Neuropathy Indicated by 4D Label-Free Quantitative Proteomics

(2022) Xinwei Yang et al.   Oxidative Medicine and Cellular Longevity

LncRNA UC.360+ shRNA Improves Diabetic Cardiac Sympathetic Dysfunction Mediated by the P2X4 Receptor in the Stellate Ganglion

(2021) Liran Shi et al.   ACS Chemical Neuroscience

Acinar cell NLRP3 inflammasome and GSDMD activation mediates pyroptosis and systemic inflammation in acute pancreatitis

(2021) Lin Gao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy

(2021) Nikole J. Byrne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Crocin alleviates the inflammation and oxidative stress responses associated with diabetic nephropathy in rats via NLRP3 inflammasomes

(2021) Linjuan Zhang et al.   LIFE SCIENCES

Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis

(2021) Renyikun Yuan et al.   PHARMACOLOGICAL RESEARCH

NLRP3 Inflammasome in Diabetic Cardiomyopathy and Exercise Intervention

(2021) Yi Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway

(2021) Jia-shang Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protective effect of sinomenine against inflammation and oxidative stress in gestational diabetes mellitus in female rats via TLR4/MyD88/NF‐κB signaling pathway

(2021) Yanbing Li et al.   JOURNAL OF FOOD BIOCHEMISTRY

The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages

(2021) Wenyun Zeng et al.   Scientific Reports

Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells

(2021) Lei Hong et al.   Frontiers in Molecular Biosciences

The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis

(2021) Bo Shu et al.   Cell Death Discovery

Sirtuin 3 deficiency exacerbates diabetic cardiomyopathy via necroptosis enhancement and NLRP3 activation

(2020) Shu Song et al.   ACTA PHARMACOLOGICA SINICA

TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage

(2020) Pengfei Xu et al.   Translational Stroke Research

Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia

(2018) Xuan Sheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TRPM2 dependence of ROS-induced NLRP3 activation in Alzheimer's disease

(2018) Malihe Aminzadeh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protective effect of ginsenoside metabolite compound K against diabetic nephropathy by inhibiting NLRP3 inflammasome activation and NF-κB/p38 signaling pathway in high-fat diet/streptozotocin-induced diabetic mice

(2018) Wu Song et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease

(2017) Honglei Guo et al.   MEDIATORS OF INFLAMMATION

AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication

(2017) Thinesshwary Yogarajah et al.   Scientific Reports

A Mechanistic Review of Cell Death in Alcohol-Induced Liver Injury

(2016) Shaogui Wang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Screening and validation of lncRNAs and circRNAs as miRNA sponges

(2016) Giuseppe Militello et al.   BRIEFINGS IN BIOINFORMATICS

Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression

(2016) Arif Yurdagul et al.   JOURNAL OF CELL SCIENCE

Caspase-1 as a multifunctional inflammatory mediator: noncytokine maturation roles

(2016) Qian Sun et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Uncovering the roles of long noncoding RNAs in neural development and glioma progression

(2016) Alexander D. Ramos et al.   NEUROSCIENCE LETTERS

Basic biology and therapeutic implications of lncRNA

(2015) O. Khorkova et al.   ADVANCED DRUG DELIVERY REVIEWS

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Study of baicalin on sympathoexcitation induced by myocardial ischemia via P2X3 receptor in superior cervical ganglia

(2015) Jun Zhang et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Inhibiting the Inflammasome: A Chemical Perspective

(2015) Alex G. Baldwin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells

(2013) Atsushi Sato et al.   Stem Cell Research

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

(2013) B. G. Byrne et al.   mBio

Caspase-1 Deficiency Decreases Atherosclerosis in Apolipoprotein E-Null Mice

(2012) Jessica Gage et al.   CANADIAN JOURNAL OF CARDIOLOGY