Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models

Engineering exosome polymer hybrids by atom transfer radical polymerization

(2021) Sushil Lathwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular vesicles as antigen carriers for novel vaccination avenues

(2021) Mina Mehanny et al.   ADVANCED DRUG DELIVERY REVIEWS

Mononuclear phagocyte system blockade using extracellular vesicles modified with CD47 on membrane surface for myocardial infarction reperfusion injury treatment

(2021) Zilun Wei et al.   BIOMATERIALS

A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

(2020) Katherine J Susa et al.   eLife

Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

(2019) Mauro Poggio et al.   CELL

Decoy exosomes as a novel biologic reagent to antagonize inflammation

(2019) Natalie Duong et al.   International Journal of Nanomedicine

Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review

(2019) Kouichi Shiraishi et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Transfer of Functional Cargo in Exomeres

(2019) Qin Zhang et al.   Cell Reports

Hydrogel-Mediated Sustained Systemic Delivery of Mesenchymal Stem Cell-Derived Extracellular Vesicles Improves Hepatic Regeneration in Chronic Liver Failure

(2019) Soura Mardpour et al.   ACS Applied Materials & Interfaces

Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance

(2019) Akihiro Matsumoto et al.   Journal of Extracellular Vesicles

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity

(2018) Junxia Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells

(2018) Peng Wang et al.   Theranostics

Stabilization of the CD81 Large Extracellular Loop with De Novo Disulfide Bonds Improves Its Amenability for Peptide Grafting

(2018) Stefan Vogt et al.   Pharmaceutics

Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy

(2018) Parisa Yousefpour et al.   NANO LETTERS

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

Extracellular vesicles for drug delivery

(2016) Pieter Vader et al.   ADVANCED DRUG DELIVERY REVIEWS

Albumin Carriers for Cancer Theranostics: A Conventional Platform with New Promise

(2016) Qian Chen et al.   ADVANCED MATERIALS

Efficient production and enhanced tumor delivery of engineered extracellular vesicles

(2016) Dionysios C. Watson et al.   BIOMATERIALS

Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket

(2016) Brandon Zimmerman et al.   CELL

Albumin-Based Nanodevices as Drug Carriers

(2016) Ana Loureiro et al.   CURRENT PHARMACEUTICAL DESIGN

PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time

(2016) S.A.A. Kooijmans et al.   JOURNAL OF CONTROLLED RELEASE

Cell-derived vesicles for drug therapy and diagnostics: Opportunities and challenges

(2015) Gregor Fuhrmann et al.   Nano Today

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

In vivo albumin labeling and lymphatic imaging

(2014) Yu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-chain Variable Fragment Albumin Fusions Bind the Neonatal Fc Receptor (FcRn) in a Species-dependent Manner

(2013) Jan Terje Andersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

(2013) Yuki Takahashi et al.   JOURNAL OF BIOTECHNOLOGY

THE ALBUMIN-BINDING DOMAIN AS A SCAFFOLD FOR PROTEIN ENGINEERING

(2013) Johan Nilvebrant et al.   Computational and Structural Biotechnology Journal

The CD47 pathway is deregulated in human immune thrombocytopenia

(2011) Lucia Catani et al.   EXPERIMENTAL HEMATOLOGY

Binding of Albumin Promotes Bacterial Survival at the Epithelial Surface

(2010) Arne Egesten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

(2010) M. P. Chao et al.   Science Translational Medicine

Lateral organization of membrane proteins: tetraspanins spin their web

(2009) Stéphanie Charrin et al.   BIOCHEMICAL JOURNAL

Histological study on side effects and tumor targeting of a block copolymer micelle on rats

(2009) Takanori Kawaguchi et al.   JOURNAL OF CONTROLLED RELEASE

Protein nanoparticles as drug carriers in clinical medicine

(2008) Michael J. Hawkins et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering of a femtomolar affinity binding protein to human serum albumin

(2008) A. Jonsson et al.   PROTEIN ENGINEERING DESIGN & SELECTION