Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review
Authors
Keywords
-
Journal
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
Volume 20, Issue 1, Pages 324-336
Publisher
Informa UK Limited
Online
2019-04-15
DOI
10.1080/14686996.2019.1590126
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Zwitterionic Nanocages Overcome the Efficacy Loss of Biologic Drugs
- (2018) Bowen Li et al. ADVANCED MATERIALS
- Polypeptides with High Zwitterion Density for Safe and Effective Therapeutics
- (2018) Peng Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A hydroxyl PEG version of PEGylated liposomes and its impact on anti-PEG IgM induction and on the accelerated clearance of PEGylated liposomes
- (2018) Taro Shimizu et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens
- (2018) Hidenori Ando et al. JOURNAL OF CONTROLLED RELEASE
- Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro
- (2018) Barry Neun et al. MOLECULES
- Evaluating the Accelerated Blood Clearance Phenomenon of PEGylated Nanoemulsions in Rats by Intraperitoneal Administration
- (2018) Yuqing Su et al. AAPS PHARMSCITECH
- Antibody–Antigen Interaction Dynamics Revealed by Analysis of Single-Molecule Equilibrium Fluctuations on Individual Plasmonic Nanoparticle Biosensors
- (2018) Srdjan S. Aćimović et al. ACS Nano
- Enhanced Opsonization-Independent Phagocytosis and High Response Ability to Opsonized Antigen–Antibody Complexes: A New Role of Kupffer Cells in the Accelerated Blood Clearance Phenomenon upon Repeated Injection of PEGylated Emulsions
- (2018) Xiaobo Cheng et al. MOLECULAR PHARMACEUTICS
- A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics
- (2018) Taro Shimizu et al. PHARMACEUTICAL RESEARCH
- Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity
- (2017) Yu Mima et al. JOURNAL OF CONTROLLED RELEASE
- Complement activation turnover on surfaces of nanoparticles
- (2017) S.M. Moghimi et al. Nano Today
- Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a C-C-O Backbone
- (2017) Justin McCallen et al. ACS Biomaterials-Science & Engineering
- Nanoparticle Interactions with the Immune System: Clinical Implications for Liposome-Based Cancer Chemotherapy
- (2017) Ninh M. La-Beck et al. Frontiers in Immunology
- Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a C-C-O Backbone
- (2017) Justin McCallen et al. ACS Biomaterials Science & Engineering
- Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
- (2016) Nancy J. Ganson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Exploring the relationship between anti-PEG IgM behaviors and PEGylated nanoparticles and its significance for accelerated blood clearance
- (2016) Kouichi Shiraishi et al. JOURNAL OF CONTROLLED RELEASE
- Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation
- (2016) Peng Zhang et al. JOURNAL OF CONTROLLED RELEASE
- PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs
- (2016) Peter L. Turecek et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
- (2016) Fangfang Chen et al. Nature Nanotechnology
- The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?
- (2016) Christian Lubich et al. PHARMACEUTICAL RESEARCH
- A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity
- (2016) Yizhi Qi et al. Nature Biomedical Engineering
- Development of a Generic Anti-PEG Antibody Assay Using BioScale’s Acoustic Membrane MicroParticle Technology
- (2015) Huijin Dong et al. AAPS Journal
- Protein–polymer conjugation—moving beyond PEGylation
- (2015) Yizhi Qi et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells
- (2015) Taro Shimizu et al. IMMUNOBIOLOGY
- Determination of polymeric micelles' structural characteristics, and effect of the characteristics on pharmacokinetic behaviors
- (2015) Kouichi Shiraishi et al. JOURNAL OF CONTROLLED RELEASE
- Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity
- (2015) Peng Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PEGylated Biopharmaceuticals
- (2015) Inge A. Ivens et al. TOXICOLOGIC PATHOLOGY
- Anti-PEG immunity: emergence, characteristics, and unaddressed questions
- (2015) Qi Yang et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Modulation of Complement Activation and Amplification on Nanoparticle Surfaces by Glycopolymer Conformation and Chemistry
- (2014) Kai Yu et al. ACS Nano
- Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics
- (2014) Johan J.F. Verhoef et al. DRUG DISCOVERY TODAY
- Cancer nanomedicine and the complement system activation paradigm: Anaphylaxis and tumour growth
- (2014) S.M. Moghimi JOURNAL OF CONTROLLED RELEASE
- Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial
- (2014) Nicola Longo et al. LANCET
- Evading Immune Cell Uptake and Clearance Requires PEG Grafting at Densities Substantially Exceeding the Minimum for Brush Conformation
- (2014) Qi Yang et al. MOLECULAR PHARMACEUTICS
- Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients
- (2014) Michael S Hershfield et al. ARTHRITIS RESEARCH & THERAPY
- Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout
- (2014) Peter E Lipsky et al. ARTHRITIS RESEARCH & THERAPY
- Single-Walled Carbon Nanotube Surface Control of Complement Recognition and Activation
- (2013) Alina J. Andersen et al. ACS Nano
- Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration
- (2013) Amr S. Abu Lila et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Complement monitoring of Pluronic 127 gel and micelles: Suppression of copolymer-mediated complement activation by elevated serum levels of HDL, LDL, and apolipoproteins AI and B-100
- (2013) Islam Hamad et al. JOURNAL OF CONTROLLED RELEASE
- Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins
- (2013) Mark G.P. Saifer et al. MOLECULAR IMMUNOLOGY
- The Immunogenicity of Polyethylene Glycol: Facts and Fiction
- (2013) Huub Schellekens et al. PHARMACEUTICAL RESEARCH
- Role of the Methoxy Group in Immune Responses to mPEG-Protein Conjugates
- (2012) Merry R. Sherman et al. BIOCONJUGATE CHEMISTRY
- Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents
- (2012) Ricardo P Garay et al. Expert Opinion on Drug Delivery
- Doxil® — The first FDA-approved nano-drug: Lessons learned
- (2012) Yechezkel (Chezy) Barenholz JOURNAL OF CONTROLLED RELEASE
- Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon
- (2012) Kouichi Shiraishi et al. JOURNAL OF CONTROLLED RELEASE
- Composition Dependence of the Micellar Architecture Made from Poly(ethylene glycol)-block-Poly(partially benzyl-esterified aspartic acid)
- (2012) Yusuke Sanada et al. JOURNAL OF PHYSICAL CHEMISTRY B
- PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics
- (2012) Jillian L. Perry et al. NANO LETTERS
- Material properties in complement activation
- (2011) S. Moein Moghimi et al. ADVANCED DRUG DELIVERY REVIEWS
- Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake
- (2011) Carl D. Walkey et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Distinct Polymer Architecture Mediates Switching of Complement Activation Pathways at the Nanosphere−Serum Interface: Implications for Stealth Nanoparticle Engineering
- (2010) Islam Hamad et al. ACS Nano
- Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
- (2010) Katrin Knop et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Evasion of the Accelerated Blood Clearance Phenomenon by Coating of Nanoparticles with Various Hydrophilic Polymers
- (2010) Tsutomu Ishihara et al. BIOMACROMOLECULES
- Polymeric micelles as a new drug carrier system and their required considerations for clinical trials
- (2010) Masayuki Yokoyama Expert Opinion on Drug Delivery
- T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes
- (2010) Hiroyuki Koide et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Complement activation cascade triggered by PEG–PL engineered nanomedicines and carbon nanotubes: The challenges ahead
- (2010) S.M. Moghimi et al. JOURNAL OF CONTROLLED RELEASE
- Complement: a key system for immune surveillance and homeostasis
- (2010) Daniel Ricklin et al. NATURE IMMUNOLOGY
- Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats
- (2010) Masako Ichihara et al. Pharmaceutics
- Emerging PEGylated drugs
- (2009) Jung Seok Kang et al. EXPERT OPINION ON EMERGING DRUGS
- Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control
- (2009) Taku Satoh et al. JOURNAL OF CONTROLLED RELEASE
- Histological study on side effects and tumor targeting of a block copolymer micelle on rats
- (2009) Takanori Kawaguchi et al. JOURNAL OF CONTROLLED RELEASE
- Preparation and in vivo imaging of PEG-poly(L-lysine)-based polymeric micelle MRI contrast agents
- (2009) Kouichi Shiraishi et al. JOURNAL OF CONTROLLED RELEASE
- Accelerated Blood Clearance Was Not Induced for a Gadolinium-Containing PEG-poly(L-lysine)-Based Polymeric Micelle in Mice
- (2009) Huili Ma et al. PHARMACEUTICAL RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More