Viral Circular RNAs and Their Possible Roles in Virus-Host Interaction

Human Papillomavirus Type 16 Circular RNA Is Barely Detectable for the Claimed Biological Activity

(2022) Lulu Yu et al.   mBio

hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs

(2022) Xi Zhang et al.   Emerging Microbes & Infections

Regulation of IRF3 activation in human antiviral signaling pathways

(2022) Mariya AL Hamrashdi et al.   BIOCHEMICAL PHARMACOLOGY

Circular RNAs in atherosclerosis

(2022) Xiaoni Huang et al.   CLINICA CHIMICA ACTA

Micropeptide vsp21 translated by Reovirus circular RNA 000048 attenuates viral replication

(2022) Yunshan Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Marek’s Disease Virus Virulence Genes Encode Circular RNAs

(2022) Alexis S. Chasseur et al.   JOURNAL OF VIROLOGY

A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma

(2022) Jin-Ling Duan et al.   Molecular Cancer

Thymus capitatus flavonoids inhibit infection of Kaposi's sarcoma‐associated herpesvirus

(2022) Marwa Mekni‐Toujani et al.   FEBS Open Bio

CircRPAP2 regulates the alternative splicing of PTK2 by binding to SRSF1 in breast cancer

(2022) Yunhe Yu et al.   Cell Death Discovery

circRNA circ_102049 Implicates in Pancreatic Ductal Adenocarcinoma Progression through Activating CD80 by Targeting miR-455-3p

(2021) Jie Zhu et al.   MEDIATORS OF INFLAMMATION

CircINSR Regulates Fetal Bovine Muscle and Fat Development

(2021) Xuemei Shen et al.   Frontiers in Cell and Developmental Biology

Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus

(2021) Rong Yang et al.   PLoS Pathogens

HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic Protein

(2021) Yan Li et al.   Advanced Science

Reverse complementary matches simultaneously promote both back-splicing and exon-skipping

(2021) Dong Cao   BMC GENOMICS

AVPIden: a new scheme for identification and functional prediction of antiviral peptides based on machine learning approaches

(2021) Yuxuan Pang et al.   BRIEFINGS IN BIOINFORMATICS

Epstein-Barr virus-encoded circular RNA circBART2.2 promotes immune escape of nasopharyngeal carcinoma by regulating PD-L1

(2021) Junshang Ge et al.   CANCER RESEARCH

circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating the Wnt/beta-catenin pathway

(2021) Yaming Li et al.   MOLECULAR THERAPY

NOVA2 regulates neural circRNA biogenesis

(2021) David Knupp et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of a novel Epstein-Barr Virus-encoded circular RNA from LMP-2 Gene

(2021) Ke-En Tan et al.   Scientific Reports

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

(2021) Jessica SY Ho et al.   eLife

Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs

(2021) Takanobu Tagawa et al.   Frontiers in Microbiology

Hepatocellular carcinoma progression mediated by hepatitis B virus-encoded circRNA HBV_circ_1 through interaction with CDK1

(2021) Min Zhu et al.   Molecular Therapy-Nucleic Acids

Characterizing viral circRNAs and their application in identifying circRNAs in viruses

(2021) Mengting Niu et al.   BRIEFINGS IN BIOINFORMATICS

FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development

(2021) Teresa Chioccarelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection

(2021) Yunshan Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Circular RNA mediated gene regulation in chronic diabetic complications

(2021) Nikhil S. Patil et al.   Scientific Reports

A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6

(2021) Lu Wang et al.   Clinical and Translational Medicine

m6A-dependent biogenesis of circular RNAs in male germ cells

(2020) Chong Tang et al.   CELL RESEARCH

Biogenesis and Functions of Circular RNAs Come into Focus

(2020) Mei-Sheng Xiao et al.   TRENDS IN CELL BIOLOGY

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

(2020) Bizunesh Abere et al.   mBio

Epstein–Barr virus‐derived circular RNA LMP 2A induces stemness in EBV ‐associated gastric cancer

(2020) Li‐ping Gong et al.   EMBO REPORTS

Identification of circRNA-Associated-ceRNA Networks Involved in Milk Fat Metabolism under Heat Stress

(2020) Dongyang Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p/MMP2 pathway

(2020) Xiaobai Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Identification and functional prediction of soybean CircRNAs involved in low-temperature responses

(2020) Xuesong Wang et al.   JOURNAL OF PLANT PHYSIOLOGY

The Race between Host Antiviral Innate Immunity and the Immune Evasion Strategies of Herpes Simplex Virus 1

(2020) Huifang Zhu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Regulation of the parental gene GRM4 by circGrm4 RNA transcript and glutamate-mediated neurovascular toxicity in eyes

(2020) Wintana Eyob et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Arabidopsis thaliana cbp80, c2h2, and flk Knockout Mutants Accumulate Increased Amounts of Circular RNAs

(2020) Anna Philips et al.   Cells

Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network

(2020) Bizunesh Abere et al.   mBio

Grass carp reovirus encoding circular RNAs with antiviral activity

(2020) Jun Pan et al.   AQUACULTURE

Circular RNA: an important player with multiple facets to regulate its parental gene expression

(2020) Tong Shao et al.   Molecular Therapy-Nucleic Acids

Identification of virus-encoded circular RNA

(2019) Jun-ting Huang et al.   VIROLOGY

Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity

(2019) Chu-Xiao Liu et al.   CELL

Molecular determinants of metazoan tricRNA biogenesis

(2019) Casey A Schmidt et al.   NUCLEIC ACIDS RESEARCH

Gammaherpesvirus RNAs Come Full Circle

(2019) Nathan A. Ungerleider et al.   mBio

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

(2019) Jiawei Zhao et al.   Nature Communications

Pre-mRNA structures forming circular RNAs

(2019) Justin R. Welden et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

NUDT21 regulates circRNA cyclization and ceRNA crosstalk in hepatocellular carcinoma

(2019) Xiaojing Li et al.   ONCOGENE

Knockdown of EBV-encoded circRNA circRPMS1 suppresses nasopharyngeal carcinoma cell proliferation and metastasis through sponging multiple miRNAs

(2019) Qianwen Liu et al.   Cancer Management and Research

Comprehensive analysis of circRNA expression pattern and circRNA–mRNA–miRNA network in Ctenopharyngodon idellus kidney (CIK) cells after grass carp reovirus (GCRV) infection

(2019) Bo Liu et al.   AQUACULTURE

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization

(2019) Vittoria Pagliarini et al.   NUCLEIC ACIDS RESEARCH

A Tug of War: DNA-Sensing Antiviral Innate Immunity and Herpes Simplex Virus Type I Infection

(2019) Yingying Lin et al.   Frontiers in Microbiology

Grass carp reovirus capsid protein interacts with cellular proteasome subunit beta-type 7: Evidence for the involvement of host proteasome during aquareovirus infection

(2019) Longlong Wang et al.   FISH & SHELLFISH IMMUNOLOGY

miR-26a Inhibits Feline Herpesvirus 1 Replication by Targeting SOCS5 and Promoting Type I Interferon Signaling

(2019) Jikai Zhang et al.   Viruses-Basel

RNA-binding protein trinucleotide repeat-containing 6A regulates the formation of circular RNA circ0006916, with important functions in lung cancer cells

(2018) Xin Dai et al.   CARCINOGENESIS

A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs

(2018) Chuan Huang et al.   GENES & DEVELOPMENT

Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1

(2018) Chunfu Zheng   JOURNAL OF VIROLOGY

DHX9 regulates production of hepatitis B virus-derived circular RNA and viral protein levels

(2018) Kazuma Sekiba et al.   Oncotarget

Circular RNA ciRS-7 triggers the migration and invasion of esophageal squamous cell carcinoma via miR-7/KLF4 and NF-κB signals

(2018) Hairong Huang et al.   CANCER BIOLOGY & THERAPY

Circular RNA alterations in the Bombyx mori midgut following B. mori nucleopolyhedrovirus infection

(2018) Xiaolong Hu et al.   MOLECULAR IMMUNOLOGY

Circular DNA tumor viruses make circular RNAs

(2018) Tuna Toptan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Epstein Barr virus circRNAome

(2018) Nathan Ungerleider et al.   PLoS Pathogens

Comparative analysis of gammaherpesvirus circRNA repertoires: conserved and unique viral circRNAs.

(2018) Nathan Ungerleider et al.   JOURNAL OF VIROLOGY

Antisense RNA: the new favorite in genetic research

(2018) Jian-zhong Xu et al.   Journal of Zhejiang University-SCIENCE B

Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA

(2018) Takanobu Tagawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nuclear export of circular RNAs is primarily defined by their length

(2018) Zhengguo Li et al.   RNA Biology

Sensing Self and Foreign Circular RNAs by Intron Identity

(2017) Y. Grace Chen et al.   MOLECULAR CELL

Antiviral Immunity and Circular RNA: No End in Sight

(2017) Cristhian Cadena et al.   MOLECULAR CELL

Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection

(2017) Xiang Li et al.   MOLECULAR CELL

Identification and characterization of circular RNAs in the silkworm midgut following Bombyx mori cytoplasmic polyhedrosis virus infection

(2017) Xiaolong Hu et al.   RNA Biology

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

(2017) Lorenzo Errichelli et al.   Nature Communications

A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair

(2017) Yan Zeng et al.   Theranostics

The neurogenetics of alternative splicing

(2016) Celine K. Vuong et al.   NATURE REVIEWS NEUROSCIENCE

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Evasion of host antiviral innate immunity by HSV-1, an update

(2016) Chenhe Su et al.   Virology Journal

The Biogenesis of Nascent Circular RNAs

(2016) Yang Zhang et al.   Cell Reports

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Combinatorial control ofDrosophilacircular RNA expression by intronic repeats, hnRNPs, and SR proteins

(2015) Marianne C. Kramer et al.   GENES & DEVELOPMENT

Transcriptome-wide investigation of circular RNAs in rice

(2015) Tingting Lu et al.   RNA

Exon Circularization Requires Canonical Splice Signals

(2015) Stefan Starke et al.   Cell Reports

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

(2015) Andranik Ivanov et al.   Cell Reports

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

Short intronic repeat sequences facilitate circular RNA production

(2014) Dongming Liang et al.   GENES & DEVELOPMENT

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Circular RNAs: diversity of form and function

(2014) Erika Lasda et al.   RNA

Transcriptome-wide discovery of circular RNAs in Archaea

(2011) Miri Danan et al.   NUCLEIC ACIDS RESEARCH

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS