DNA Oxidative Damage as a Sensitive Genetic Endpoint to Detect the Genotoxicity Induced by Titanium Dioxide Nanoparticles

Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines

(2022) Pégah Jalili et al.   Particle and Fibre Toxicology

The application of existing genotoxicity methodologies for grouping of nanomaterials: towards an integrated approach to testing and assessment

(2022) Rachel Verdon et al.   Particle and Fibre Toxicology

Titanium dioxide nanoparticles induced reactive oxygen species (ROS) related changes of metabolomics signatures in human normal bronchial epithelial (BEAS-2B) cells

(2022) Jiahe Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of Titanium Dioxide Nanoparticles on Cell Growth and Migration of A549 Cells under Simulated Microgravity

(2022) Mei Wang et al.   Nanomaterials

Industrial-relevant TiO2 types do not promote cytotoxicity in the A549 or TK6 cell lines regardless of cell specific interaction

(2022) Stephen J. Evans et al.   TOXICOLOGY IN VITRO

In Vitro Three‐Dimensional Liver Models for Nanomaterial DNA Damage Assessment

(2021) Samantha V. Llewellyn et al.   Small

Analysis of cytotoxicity and genotoxicity in a short-term dependent manner induced by a new titanium dioxide nanoparticle in murine fibroblast cells

(2021) Matheus Pedrino et al.   TOXICOLOGY MECHANISMS AND METHODS

Advances in genotoxicity of titanium dioxide nanoparticles in vivo and in vitro

(2021) Jiaqi Shi et al.   NanoImpact

Synthesis of encapsulated fish oil using whey protein isolate to prevent the oxidative damage and cytotoxicity of titanium dioxide nanoparticles in rats

(2021) Mosaad A. Abdel-Wahhab et al.   Heliyon

Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vitro: a Systematic Review of the Literature and Meta-analysis

(2020) Chunmei Ling et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Rethinking Nano‐TiO 2 Safety: Overview of Toxic Effects in Humans and Aquatic Animals

(2020) Zhen Luo et al.   Small

Titanium dioxide nanoparticle genotoxicity: A review of recent in vivo and in vitro studies

(2020) Mohammad Rafiq Wani et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Genotoxicity of Nanomaterials: Advanced In Vitro Models and High Throughput Methods for Human Hazard Assessment—A Review

(2020) Yvonne Kohl et al.   Nanomaterials

Tissue-specific genotoxicity and antioxidant imbalance of titanium dioxide nanoparticles (NPTiO2) and inorganic lead (PbII) in a neotropical fish species

(2020) Laís Fernanda Oya-Silva et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Shape-engineered titanium dioxide nanoparticles (TiO2-NPs): cytotoxicity and genotoxicity in bronchial epithelial cells

(2019) Marta Gea et al.   FOOD AND CHEMICAL TOXICOLOGY

The size‐dependent genotoxic potentials of titanium dioxide nanoparticles to endothelial cells

(2019) Fen Liao et al.   ENVIRONMENTAL TOXICOLOGY

Mechanisms of titanium dioxide nanoparticle‐induced oxidative stress and modulation of plasma glucose in mice

(2019) Hailong Hu et al.   ENVIRONMENTAL TOXICOLOGY

Evaluation of cytogenotoxicity and oxidative stress parameters in male Swiss mice co-exposed to titanium dioxide and zinc oxide nanoparticles

(2019) Opeoluwa Fadoju et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Understanding of ROS-Inducing Strategy in Anticancer Therapy

(2019) Su Ji Kim et al.   Oxidative Medicine and Cellular Longevity

Genotoxicity Assessment of Nanomaterials: Recommendations on Best Practices, Assays, and Methods

(2018) Rosalie Elespuru et al.   TOXICOLOGICAL SCIENCES

Critical review of the safety assessment of titanium dioxide additives in food

(2018) Hans Christian Winkler et al.   JOURNAL OF NANOBIOTECHNOLOGY

Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials

(2017) Glen M DeLoid et al.   Nature Protocols

Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles

(2016) M. Biola-Clier et al.   MUTAGENESIS

NanoGenotoxicology: present and the future

(2016) Shareen H. Doak et al.   MUTAGENESIS

Genotoxicity and gene expression analyses of liver and lung tissues of mice treated with titanium dioxide nanoparticles

(2016) Yan Li et al.   MUTAGENESIS

Toxicity of Nano-Titanium Dioxide (TiO2-NP) Through Various Routes of Exposure: a Review

(2015) Muhammad Shakeel et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms

(2015) Nazanin Golbamaki et al.   Nanoscale

Advanced computational modeling for in vitro nanomaterial dosimetry

(2015) Glen M. DeLoid et al.   Particle and Fibre Toxicology

DNA Damaging Potential of Photoactivated P25 Titanium Dioxide Nanoparticles

(2014) Elijah J. Petersen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genotoxicity of titanium dioxide nanoparticles

(2014) Tao Chen et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro

(2014) Zhangjian Chen et al.   TOXICOLOGY LETTERS

Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

Oxidative Stress Generated Damage to DNA by Gastrointestinal Exposure to Insoluble Particles

(2012) P. Moller et al.   CURRENT MOLECULAR MEDICINE

Cytotoxicity of titanium dioxide nanoparticles differs in four liver cells from human and rat

(2011) BaoYong Sha et al.   COMPOSITES PART B-ENGINEERING

Titanium Dioxide Nanoparticles Induce Oxidative Stress-Mediated Apoptosis in Human Keratinocyte Cells

(2011) RiteshK. Shukla et al.   Journal of Biomedical Nanotechnology

Titanium dioxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in human amnion epithelial (WISH) cells

(2011) Quaiser Saquib et al.   TOXICOLOGY IN VITRO

Rationale of genotoxicity testing of nanomaterials: Regulatory requirements and appropriateness of available OECD test guidelines

(2010) David B. Warheit et al.   Nanotoxicology

Chemoprotective effect of N-acetylcysteine (NAC) on cellular oxidative damages and apoptosis induced by nano titanium dioxide under UVA irradiation

(2010) Chengbin Xue et al.   TOXICOLOGY IN VITRO

Intracellular distribution, geno- and cytotoxic effects of nanosized titanium dioxide particles in the anatase crystal phase on human nasal mucosa cells

(2010) Stephan Hackenberg et al.   TOXICOLOGY LETTERS

Estimates of Upper Bounds and Trends in Nano-TiO2Production As a Basis for Exposure Assessment

(2009) Christine Ogilvie Robichaud et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Combining the in vivo comet and micronucleus assays: a practical approach to genotoxicity testing and data interpretation

(2009) Marie Z. Vasquez   MUTAGENESIS

Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells

(2009) Kirsten Gerloff et al.   Nanotoxicology

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells

(2009) Kunal Bhattacharya et al.   Particle and Fibre Toxicology

Cytotoxicity of Titanium Dioxide Nanoparticles in Mouse Fibroblast Cells

(2008) Cheng-Yu Jin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genotoxic and cytotoxic potential of titanium dioxide (TiO2) nanoparticles on fish cells in vitro

(2008) William F. Vevers et al.   ECOTOXICOLOGY

Genotoxicity investigations on nanomaterials: Methods, preparation and characterization of test material, potential artifacts and limitations—Many questions, some answers

(2008) Robert Landsiedel et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH