Virofree, an Herbal Medicine-Based Formula, Interrupts the Viral Infection of Delta and Omicron Variants of SARS-CoV-2

Molecular mechanism, diagnosis, and potential treatment for novel coronavirus (COVID-19): a current literature review and perspective

(2021) Yashwant Kumar Ratre et al.   3 Biotech

SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines

(2021) Yuichiro J. Suzuki et al.   Vaccines

Honeysuckle Aqueous Extracts Induced let-7a Suppress EV71 Replication and Pathogenesis In Vitro and In Vivo and Is Predicted to Inhibit SARS-CoV-2

(2021) Ying-Ray Lee et al.   Viruses-Basel

Syncytia formation during SARS-CoV-2 lung infection: a disastrous unity to eliminate lymphocytes

(2021) Liangyu Lin et al.   CELL DEATH AND DIFFERENTIATION

The emergence of new strains of SARS-CoV-2. What does it mean for COVID-19 vaccines?

(2021) Md Kamal Hossain et al.   Expert Review of Vaccines

Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia

(2021) Luca Braga et al.   NATURE

From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?

(2021) Jacob E. Michalski et al.   Translational Research

Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection

(2021) Ryan J. Farr et al.   PLoS Pathogens

Remdesivir treatment in hospitalized patients with COVID-19: a comparative analysis of in-hospital all-cause mortality in a large multi-center observational cohort

(2021) Essy Mozaffari et al.   CLINICAL INFECTIOUS DISEASES

SARS‐CoV‐2 Alpha, Beta, and Delta variants display enhanced Spike‐mediated syncytia formation

(2021) Maaran Michael Rajah et al.   EMBO JOURNAL

Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors

(2021) Sarah Huff et al.   JOURNAL OF MEDICINAL CHEMISTRY

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

(2021) Salim S Abdool Karim et al.   LANCET

Omicron likely to weaken COVID vaccine protection

(2021) Ewen Callaway   NATURE

Circulating microRNA profiles predict the severity of COVID-19 in hospitalized patients

(2021) DAVID de GONZALO-CALVO et al.   Translational Research

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

First Case of 2019 Novel Coronavirus in the United States

(2020) Michelle L. Holshue et al.   NEW ENGLAND JOURNAL OF MEDICINE

DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression

(2020) Hongyan Guo et al.   Viruses-Basel

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

(2020) Yeming Wang et al.   LANCET

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

Remdesivir for 5 or 10 Days in Patients with Severe Covid-19

(2020) Jason D. Goldman et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

(2020) Wenhao Dai et al.   SCIENCE

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Molecular immune pathogenesis and diagnosis of COVID-19

(2020) Xiaowei Li et al.   Journal of Pharmaceutical Analysis

Potential of Flavonoid-Inspired Phytomedicines against COVID-19

(2020) Wilfred Ngwa et al.   MOLECULES

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

(2020) Antonio E. Muruato et al.   Nature Communications

Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infection

(2020) Müşerref Duygu Saçar Demirci et al.   PeerJ

The Lung Macrophage in SARS-CoV-2 Infection: A Friend or a Foe?

(2020) Zaid Abassi et al.   Frontiers in Immunology

Serum Iron Level as a Potential Predictor of Coronavirus Disease 2019 Severity and Mortality: A Retrospective Study

(2020) Kang Zhao et al.   Open Forum Infectious Diseases

Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage

(2020) Tzu-Hau Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Syncytia formation by SARS‐CoV‐2 infected cells

(2020) Julian Buchrieser et al.   EMBO JOURNAL

COVID-19: fighting the invisible enemy with microRNAs

(2020) Neeraj Chauhan et al.   Expert Review of Anti-Infective Therapy

In-silico screening of plant-derived antivirals against main protease, 3CLpro and endoribonuclease, NSP15 proteins of SARS-CoV-2

(2020) Aniket Sharma et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Ferritin in the coronavirus disease 2019 (COVID‐19): A systematic review and meta‐analysis

(2020) Linlin Cheng et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

COVID-19 and multiorgan failure: A narrative review on potential mechanisms

(2020) Tahmineh Mokhtari et al.   JOURNAL OF MOLECULAR HISTOLOGY

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects

(2020) Ya-Wen Cheng et al.   Cell Reports

Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3’UTR of pro-inflammatory mRNAs

(2020) Jessica Gasparello et al.   MEDICAL HYPOTHESES

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

(2020) Shalki Choudhary et al.   MICROBIAL PATHOGENESIS

SARS-CoV-2 infection: can ferroptosis be a potential treatment target for multiple organ involvement?

(2020) Ming Yang et al.   Cell Death Discovery

SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells

(2020) Yuichiro J. Suzuki et al.   VASCULAR PHARMACOLOGY

In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small‐cell lung cancer

(2019) Tse‐Hung Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo

(2019) Yuki Shibata et al.   PLoS One

Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights

(2018) Diego de Sá Coutinho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells

(2018) Mami Sato et al.   Scientific Reports

Human Disease Ontology 2018 update: classification, content and workflow expansion

(2018) Lynn M Schriml et al.   NUCLEIC ACIDS RESEARCH

Anti-TNFα therapy in inflammatory lung diseases

(2017) Rama Malaviya et al.   PHARMACOLOGY & THERAPEUTICS

Macrophages and Iron Metabolism

(2016) Miguel P. Soares et al.   IMMUNITY

An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy

(2016) Thanigaimalai Pillaiyar et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Papyro Comparison of TMM (edgeR), RLE (DESeq2), and MRN Normalization Methods for a Simple Two-Conditions-Without-Replicates RNA-Seq Experimental Design

(2016) Elie Maza   Frontiers in Genetics

Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models

(2014) Hamideh Parhiz et al.   PHYTOTHERAPY RESEARCH

TNF-α/NF-κB Signaling in the CNS: Possible Connection to EPHB2

(2013) Paul D. Pozniak et al.   Journal of Neuroimmune Pharmacology

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Control of Cytokine mRNA Expression by RNA-binding Proteins and microRNAs

(2012) V. Palanisamy et al.   JOURNAL OF DENTAL RESEARCH

From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations

(2009) P. Du et al.   BIOINFORMATICS

DEGseq: an R package for identifying differentially expressed genes from RNA-seq data

(2009) Likun Wang et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS