Molecular mechanism, diagnosis, and potential treatment for novel coronavirus (COVID-19): a current literature review and perspective
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanism, diagnosis, and potential treatment for novel coronavirus (COVID-19): a current literature review and perspective
Authors
Keywords
-
Journal
3 Biotech
Volume 11, Issue 2, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-26
DOI
10.1007/s13205-021-02657-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China
- (2020) Yueying Pan et al. EUROPEAN RADIOLOGY
- The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
- (2020) Calvin J Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens
- (2020) Jasper Fuk-Woo Chan et al. JOURNAL OF CLINICAL MICROBIOLOGY
- The 2019‐new coronavirus epidemic: Evidence for virus evolution
- (2020) Domenico Benvenuto et al. JOURNAL OF MEDICAL VIROLOGY
- Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China
- (2020) Fei Yu et al. MICROBES AND INFECTION
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
- (2020) Guangdi Li et al. NATURE REVIEWS DRUG DISCOVERY
- Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
- (2020) Emmie de Wit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing
- (2020) Xingzhi Xie et al. RADIOLOGY
- Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission
- (2020) Xintian Xu et al. Science China-Life Sciences
- Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts’ consensus statement
- (2020) Kunling Shen et al. World Journal of Pediatrics
- HIV-1 did not contribute to the 2019-nCoV genome
- (2020) Chuan Xiao et al. Emerging Microbes & Infections
- Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
- (2020) Jasper Fuk-Woo Chan et al. Emerging Microbes & Infections
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome
- (2020) Zhe Xu et al. Lancet Respiratory Medicine
- Recent advances and perspectives of nucleic acid detection for coronavirus
- (2020) Minzhe Shen et al. Journal of Pharmaceutical Analysis
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
- (2020) Shuai Xia et al. CELL RESEARCH
- High-resolution computed tomography manifestations of COVID-19 infections in patients of different ages
- (2020) Zuhua Chen et al. EUROPEAN JOURNAL OF RADIOLOGY
- The epidemiology, diagnosis and treatment of COVID-19
- (2020) Pan Zhai et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
- (2020) Jacques Fantini et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Clinical characteristics of 25 death cases with COVID-19: A retrospective review of medical records in a single medical center, Wuhan, China
- (2020) Xun Li et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)
- (2020) Phulen Sarma et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Convalescent plasma transfusion for the treatment of COVID‐19: Systematic review
- (2020) Karthick Rajendran et al. JOURNAL OF MEDICAL VIROLOGY
- How will country-based mitigation measures influence the course of the COVID-19 epidemic?
- (2020) Roy M Anderson et al. LANCET
- New therapeutic opportunities for COVID-19 patients with Tocilizumab: Possible correlation of interleukin-6 receptor inhibitors with osteonecrosis of the jaws
- (2020) Francesco Bennardo et al. ORAL ONCOLOGY
- In Silico Discovery of Candidate Drugs against Covid-19
- (2020) Claudia Cava et al. Viruses-Basel
- Molecular Mechanism of Evolution and Human Infection with SARS-CoV-2
- (2020) Jiahua He et al. Viruses-Basel
- Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
- (2020) Xiuyuan Ou et al. Nature Communications
- Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths
- (2020) William B. Grant et al. Nutrients
- Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
- (2020) Wei Tang et al. BMJ-British Medical Journal
- Covid-19: WHO declares pandemic because of “alarming levels” of spread, severity, and inaction
- (2020) Elisabeth Mahase BMJ-British Medical Journal
- Molecular immune pathogenesis and diagnosis of COVID-19
- (2020) Xiaowei Li et al. Journal of Pharmaceutical Analysis
- SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far
- (2020) Firas A. Rabi et al. Pathogens
- Organ-specific manifestations of COVID-19 infection
- (2020) Maria Gavriatopoulou et al. CLINICAL AND EXPERIMENTAL MEDICINE
- Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic
- (2020) Amin Gasmi et al. CLINICAL IMMUNOLOGY
- Herd immunity – estimating the level required to halt the COVID-19 epidemics in affected countries
- (2020) Kin On Kwok et al. JOURNAL OF INFECTION
- Drug treatments for covid-19: living systematic review and network meta-analysis
- (2020) Reed AC Siemieniuk et al. BMJ-British Medical Journal
- COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses
- (2020) Muhammad Adnan Shereen et al. Journal of Advanced Research
- Current updates on the European and WHO registered clinical trials of coronavirus disease 2019 (COVID-19)
- (2020) Henu Kumar Verma et al. Biomedical Journal
- The Outcome of Hydroxychloroquine in Patients Treated for COVID-19: Systematic Review and Meta-Analysis
- (2020) Teshale Ayele Mega et al. Canadian Respiratory Journal
- Decreased Mortality in Coronavirus Disease 2019 Patients Treated With Tocilizumab: A Rapid Systematic Review and Meta-analysis of Observational Studies
- (2020) Jishnu Malgie et al. CLINICAL INFECTIOUS DISEASES
- Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis
- (2020) Thibault Fiolet et al. CLINICAL MICROBIOLOGY AND INFECTION
- Dynamic Propagation and Impact of Pandemic Influenza A (2009 H1N1) in Children: A Detailed Review
- (2020) Yashwant Kumar Ratre et al. CURRENT MICROBIOLOGY
- Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis
- (2019) Adrian R Martineau et al. HEALTH TECHNOLOGY ASSESSMENT
- Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
- (2019) Alexandra C. Walls et al. CELL
- The Third Plague Pandemic in Europe
- (2019) Barbara Bramanti et al. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Molecular epidemiology, evolution and phylogeny of SARS coronavirus
- (2019) Hayes K.H. Luk et al. INFECTION GENETICS AND EVOLUTION
- SHERLOCK: nucleic acid detection with CRISPR nucleases
- (2019) Max J. Kellner et al. Nature Protocols
- Gangliosides interact with synaptotagmin to form the high-affinity receptor complex for botulinum neurotoxin B
- (2019) Alessandra Flores et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds—Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds
- (2018) Mariangela Rondanelli et al. Evidence-based Complementary and Alternative Medicine
- Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology
- (2017) Rudragouda Channappanavar et al. Seminars in Immunopathology
- Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming
- (2017) Fazle Rabbi Chowdhury et al. Annals of Clinical Microbiology and Antimicrobials
- Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data
- (2017) Adrian R Martineau et al. BMJ-British Medical Journal
- Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data
- (2017) Adrian R Martineau et al. BMJ-British Medical Journal
- Effect of vitamin D supplementation on non-skeletal disorders: a systematic review of meta-analyses and randomised trials
- (2017) Philippe Autier et al. Lancet Diabetes & Endocrinology
- Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data
- (2017) Lars Rejnmark et al. PLoS One
- Pre-fusion structure of a human coronavirus spike protein
- (2016) Robert N. Kirchdoerfer et al. NATURE
- SARS and MERS: recent insights into emerging coronaviruses
- (2016) Emmie de Wit et al. NATURE REVIEWS MICROBIOLOGY
- Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection
- (2015) Xinyi Tu et al. JOURNAL OF INFECTION
- Combined DNA, toxicological and heavy metal analyses provides an auditing toolkit to improve pharmacovigilance of traditional Chinese medicine (TCM)
- (2015) Megan L. Coghlan et al. Scientific Reports
- Deciphering the Glycolipid Code of Alzheimer's and Parkinson's Amyloid Proteins Allowed the Creation of a Universal Ganglioside-Binding Peptide
- (2014) Nouara Yahi et al. PLoS One
- Substitution at Aspartic Acid 1128 in the SARS Coronavirus Spike Glycoprotein Mediates Escape from a S2 Domain-Targeting Neutralizing Monoclonal Antibody
- (2014) Oi-Wing Ng et al. PLoS One
- Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
- (2014) Jean Kaoru Millet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Age-Associated Changes in Immune Function: Impact of Vitamin E Intervention and the Underlying Mechanisms
- (2014) Dayong Wu et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- The mercurial nature of neutrophils: still an enigma in ARDS?
- (2013) Andrew E. Williams et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein
- (2013) A. Heurich et al. JOURNAL OF VIROLOGY
- Vitamin D and Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- (2013) Peter Bergman et al. PLoS One
- A hexapeptide of the receptor-binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2
- (2012) Anna-Winona Struck et al. ANTIVIRAL RESEARCH
- Traditional Chinese herbal medicine as a source of molecules with antiviral activity
- (2012) Ting Li et al. ANTIVIRAL RESEARCH
- Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing
- (2012) Hatem A. Elshabrawy et al. PLoS One
- Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential
- (2011) Melissa M. Coughlin et al. REVIEWS IN MEDICAL VIROLOGY
- Human-Leukocyte Antigen Class I Cw 1502 and Class II DR 0301 Genotypes Are Associated with Resistance to Severe Acute Respiratory Syndrome (SARS) Infection
- (2011) Sheng-Fan Wang et al. VIRAL IMMUNOLOGY
- Novel Immunodominant Peptide Presentation Strategy: a Featured HLA-A*2402-Restricted Cytotoxic T-Lymphocyte Epitope Stabilized by Intrachain Hydrogen Bonds from Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein
- (2010) J. Liu et al. JOURNAL OF VIROLOGY
- Neutralizing epitopes of the SARS-CoV S-protein cluster independent of repertoire, antigen structure or mAb technology
- (2010) Jody D. Berry et al. mAbs
- Trilogy of ACE2: A peptidase in the renin–angiotensin system, a SARS receptor, and a partner for amino acid transporters
- (2010) Keiji Kuba et al. PHARMACOLOGY & THERAPEUTICS
- Mechanisms underlying the effect of vitamin D on the immune system
- (2010) Margherita T. Cantorna PROCEEDINGS OF THE NUTRITION SOCIETY
- Association of human leukocyte antigen class II alleles with severe acute respiratory syndrome in the Vietnamese population
- (2009) Naoto Keicho et al. HUMAN IMMUNOLOGY
- Coronaviruses post-SARS: update on replication and pathogenesis
- (2009) Stanley Perlman et al. NATURE REVIEWS MICROBIOLOGY
- Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
- (2009) S. Belouzard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started