Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway
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Title
Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway
Authors
Keywords
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Journal
Stem Cells International
Volume 2022, Issue -, Pages 1-15
Publisher
Hindawi Limited
Online
2022-07-15
DOI
10.1155/2022/1252557
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Note: Only part of the references are listed.- Exosomes from adipose‐derived stem cells and application to skin wound healing
- (2021) Yang An et al. CELL PROLIFERATION
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- (2020) Xing-Liang Fan et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2020) Jing Li et al. Translational Vision Science & Technology
- Next-generation stem cells — ushering in a new era of cell-based therapies
- (2020) Erin A. Kimbrel et al. NATURE REVIEWS DRUG DISCOVERY
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- (2020) Guifang Zhao et al. Stem Cell Research & Therapy
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- (2020) Wei Liu et al. Stem Cell Research & Therapy
- Human mesenchymal stromal cells and derived extracellular vesicles: Translational strategies to increase their proangiogenic potential for the treatment of cardiovascular disease
- (2020) Timo Z. Nazari-Shafti et al. Stem Cells Translational Medicine
- Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
- (2019) Yong Pan et al. JOURNAL OF CLINICAL INVESTIGATION
- Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion
- (2019) Biji Mathew et al. BIOMATERIALS
- Diabetes inhibits corneal epithelial cell migration and tight junction formation in mice and human via increasing ROS and impairing Akt signaling
- (2019) Qi-wei Jiang et al. ACTA PHARMACOLOGICA SINICA
- TNF‐α‐induced exosomal miR‐146a mediates mesenchymal stem cell‐dependent suppression of urethral stricture
- (2019) Ying‐Chun Liang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential
- (2019) Li Qiao et al. JOURNAL OF CLINICAL INVESTIGATION
- PI3K/Akt/mTOR inhibitors in cancer: At the bench and bedside
- (2019) Ali S. Alzahrani SEMINARS IN CANCER BIOLOGY
- Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications
- (2019) Kenneth W. Witwer et al. Journal of Extracellular Vesicles
- An update on PTEN modulators – a patent review
- (2019) Chandra S. Boosani et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Human umbilical cord mesenchymal stem cells ameliorate liver fibrosis in vitro and in vivo: From biological characteristics to therapeutic mechanisms
- (2019) Fei Yin et al. World Journal of Stem Cells
- Exosomal miR-21 regulates the TETs/PTENp1/PTEN pathway to promote hepatocellular carcinoma growth
- (2019) Liang-qi Cao et al. Molecular Cancer
- Mesenchymal Stem Cell-Derived Extracellular Vesicles for Corneal Wound Repair
- (2019) Hongyan Tao et al. Stem Cells International
- Exosomes derived from human umbilical vein endothelial cells promote neural stem cell expansion while maintain their stemness in culture
- (2018) Yi-Zhe Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MSC exosome works through a protein-based mechanism of action
- (2018) Wei Seong Toh et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Beclin-1-Dependent Autophagy Protects the Heart During Sepsis
- (2018) Yuxiao Sun et al. CIRCULATION
- Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction
- (2018) Yaoxiang Sun et al. ACS Nano
- PI3k/AKT signaling pathway: Erythropoiesis and beyond
- (2018) Mahjoobeh Jafari et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Exosomes from normal and diabetic human corneolimbal keratocytes differentially regulate migration, proliferation and marker expression of limbal epithelial cells
- (2018) Aleksandra Leszczynska et al. Scientific Reports
- Exosomes derived from human umbilical cord mesenchymal stem cells accelerate growth of VK2 vaginal epithelial cells through MicroRNAs in vitro
- (2018) Zhongyi Zhu et al. HUMAN REPRODUCTION
- Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers
- (2018) Chandan Kanta Das et al. MOLECULAR PHARMACEUTICS
- Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
- (2017) Francisco Vizoso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MiR-21/PTEN Axis Promotes Skin Wound Healing by Dendritic Cells Enhancement
- (2017) Zhaofeng Han et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- A microRNA feedback loop regulates global microRNA abundance during aging
- (2017) Sachi Inukai et al. RNA
- Concise Review: MSC-Derived Exosomes for Cell-Free Therapy
- (2017) Donald G. Phinney et al. STEM CELLS
- Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms
- (2017) Ben Mead et al. Stem Cells Translational Medicine
- Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth
- (2016) M.A. Lopez-Verrilli et al. NEUROSCIENCE
- Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomal MicroRNAs Suppress Myofibroblast Differentiation by Inhibiting the Transforming Growth Factor-β/SMAD2 Pathway During Wound Healing
- (2016) Shuo Fang et al. Stem Cells Translational Medicine
- MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential
- (2016) Ana Marote et al. Frontiers in Pharmacology
- Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
- (2015) Nina Heldring et al. HUMAN GENE THERAPY
- Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
- (2015) Lin Zhang et al. NATURE
- PTEN
- (2014) Carolyn A. Worby et al. Annual Review of Biochemistry
- Quantitative and stoichiometric analysis of the microRNA content of exosomes
- (2014) J. R. Chevillet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue factor triggers procoagulation in transplanted mesenchymal stem cells leading to thromboembolism
- (2013) Kohei Tatsumi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MicroRNA: Function, Detection, and Bioanalysis
- (2013) Haifeng Dong et al. CHEMICAL REVIEWS
- The widespread regulation of microRNA biogenesis, function and decay
- (2010) Jacek Krol et al. NATURE REVIEWS GENETICS
- Fate Of Culture-Expanded Mesenchymal Stem Cells in The Microvasculature
- (2008) Catalin Toma et al. CIRCULATION RESEARCH
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