Therapeutic role of extracellular vesicles derived from stem cells in cutaneous wound models: A systematic review

Advances in Analysis of Biodistribution of Exosomes by Molecular Imaging

(2020) Yong Weon Yi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exosomal miR-135a derived from human amnion mesenchymal stem cells promotes cutaneous wound healing in rats and fibroblast migration by directly inhibiting LATS2 expression

(2020) Shaoying Gao et al.   Stem Cell Research & Therapy

The proangiogenic effects of extracellular vesicles secreted by dental pulp stem cells derived from periodontally compromised teeth

(2020) Huan Zhou et al.   Stem Cell Research & Therapy

Role of TGF-β in Skin Chronic Wounds: A Keratinocyte Perspective

(2020) Sergio Liarte et al.   Cells

Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p/SIRT1-mediated autophagy

(2020) Rongfeng Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Extracellular Vesicles Derived From Human Adipose-Derived Stem Cell Prevent the Formation of Hypertrophic Scar in a Rabbit Model

(2020) Yuan-zheng Zhu et al.   ANNALS OF PLASTIC SURGERY

Engineered Human Adipose Stem-Cell-Derived Exosomes Loaded with miR-21-5p to Promote Diabetic Cutaneous Wound Healing

(2020) Qijun Lv et al.   MOLECULAR PHARMACEUTICS

Toxicological evaluation of exosomes derived from human adipose tissue-derived mesenchymal stem/stromal cells

(2020) Dae Hyun Ha et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Regenerative and protective effects of dMSC-sEVs on high-glucose-induced senescent fibroblasts by suppressing RAGE pathway and activating Smad pathway

(2020) Xiaowei Bian et al.   Stem Cell Research & Therapy

MSC-derived exosomes attenuate cell death through suppressing AIF nucleus translocation and enhance cutaneous wound healing

(2020) Guifang Zhao et al.   Stem Cell Research & Therapy

Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

(2020) Tiechao Jiang et al.   Stem Cell Research & Therapy

Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis

(2020) Kyong-Oh Shin et al.   Cells

Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration

(2020) Dae Hyun Ha et al.   Cells

Reproducible Large-Scale Isolation of Exosomes from Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells and Their Application in Acute Kidney Injury

(2020) Jun Ho Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Promising effects of exosomes isolated from menstrual blood-derived mesenchymal stem cell on wound healing process in diabetic mouse model

(2019) Razieh Dalirfardouei et al.   Journal of Tissue Engineering and Regenerative Medicine

Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap

(2019) Jüri Reimand et al.   Nature Protocols

Human embryonic stem cell-derived exosomes promote pressure ulcer healing in aged mice by rejuvenating senescent endothelial cells

(2019) Bi Chen et al.   Stem Cell Research & Therapy

Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Stimulated by Deferoxamine Accelerate Cutaneous Wound Healing by Promoting Angiogenesis

(2019) Jianing Ding et al.   Biomed Research International

Thrombin Preconditioning of Extracellular Vesicles Derived from Mesenchymal Stem Cells Accelerates Cutaneous Wound Healing by Boosting Their Biogenesis and Enriching Cargo Content

(2019) Dong Kyung Sung et al.   Journal of Clinical Medicine

Efficient Angiogenesis-Based Diabetic Wound Healing/Skin Reconstruction through Bioactive Antibacterial Adhesive Ultraviolet Shielding Nanodressing with Exosome Release

(2019) Min Wang et al.   ACS Nano

Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular vesicles

(2019) Kyong-Su Park et al.   Stem Cell Research & Therapy

MSC-Derived Exosome Promotes M2 Polarization and Enhances Cutaneous Wound Healing

(2019) Xiaoning He et al.   Stem Cells International

Exosome loaded alginate hydrogel promotes tissue regeneration in full‐thickness skin wounds: An in vivo study

(2019) Shilan Shafei et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The MSC-Derived Exosomal lncRNA H19 Promotes Wound Healing in Diabetic Foot Ulcers by Upregulating PTEN via MicroRNA-152-3p

(2019) Bo Li et al.   Molecular Therapy-Nucleic Acids

Noninvasive Assessment of Exosome Pharmacokinetics In Vivo: A Review

(2019) Do Hee Kim et al.   Pharmaceutics

Preparation of Engineered Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells with Ultrasonication for Skin Rejuvenation

(2019) Lixue Wang et al.   ACS Omega

Allogeneic mesenchymal stem cells improve the wound healing process of sheep skin

(2018) T. Martinello et al.   BMC Veterinary Research

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway

(2018) Wei Zhang et al.   EXPERIMENTAL CELL RESEARCH

Extracellular vesicles derived from mesenchymal cells: perspective treatment for cutaneous wound healing in pediatrics

(2018) Gloria Pelizzo et al.   Regenerative Medicine

An Economic Evaluation of the Impact, Cost, and Medicare Policy Implications of Chronic Nonhealing Wounds

(2018) Samuel R. Nussbaum et al.   VALUE IN HEALTH

Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis

(2018) Byong Seung Cho et al.   Stem Cell Research & Therapy

Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function

(2018) Yin Hu et al.   Theranostics

Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis

(2018) Chun-Yuan Chen et al.   Theranostics

Isolation of Extracellular Vesicles: General Methodologies and Latest Trends

(2018) Maria Yu. Konoshenko et al.   Biomed Research International

Exosomes produced from three-dimensional cultures of mesenchymal stem cells by tangential flow filtration show higher yield and improved activity

(2018) Reka Agnes Haraszti et al.   MOLECULAR THERAPY

Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid

(2018) Sara Busatto et al.   Cells

Exosomes derived from human amniotic epithelial cells accelerate wound healing and inhibit scar formation

(2017) Bin Zhao et al.   JOURNAL OF MOLECULAR HISTOLOGY

Pharmacokinetics of Exosomes—An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics

(2017) Masaki Morishita et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model

(2017) Quan Shi et al.   Frontiers in Physiology

Financial burden of diabetic foot ulcers to world: a progressive topic to discuss always

(2017) Alok Raghav et al.   Therapeutic Advances in Endocrinology and Metabolism

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

(2017) Lu Wang et al.   Scientific Reports

Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis

(2016) Pengzi Zhang et al.   ANNALS OF MEDICINE

Transition from inflammation to proliferation: a critical step during wound healing

(2016) Ning Xu Landén et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Safety evaluation of exosomes derived from human umbilical cord mesenchymal stromal cell

(2016) Li Sun et al.   CYTOTHERAPY

Exosomes Derived from Human Endothelial Progenitor Cells Accelerate Cutaneous Wound Healing by Promoting Angiogenesis Through Erk1/2 Signaling

(2016) Jieyuan Zhang et al.   International Journal of Biological Sciences

Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a

(2016) Xiaolei Liang et al.   JOURNAL OF CELL SCIENCE

Human endothelial progenitor cells-derived exosomes accelerate cutaneous wound healing in diabetic rats by promoting endothelial function

(2016) Xiaocong Li et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action

(2016) Giusy Lombardo et al.   Scientific Reports

Illuminating the physiology of extracellular vesicles

(2016) Hongyoon Choi et al.   Stem Cell Research & Therapy

Chitosan Wound Dressings Incorporating Exosomes Derived from MicroRNA-126-Overexpressing Synovium Mesenchymal Stem Cells Provide Sustained Release of Exosomes and Heal Full-Thickness Skin Defects in a Diabetic Rat Model

(2016) Shi-Cong Tao et al.   Stem Cells Translational Medicine

Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomal MicroRNAs Suppress Myofibroblast Differentiation by Inhibiting the Transforming Growth Factor-β/SMAD2 Pathway During Wound Healing

(2016) Shuo Fang et al.   Stem Cells Translational Medicine

Fabrication of hydroxyapatite/chitosan composite hydrogels loaded with exosomes derived from miR-126-3p overexpressed synovial mesenchymal stem cells for diabetic chronic wound healing

(2016) Min Li et al.   Journal of Materials Chemistry B

Cellular mechanisms of skin repair in humans and other mammals

(2016) Laure Rittié   Journal of Cell Communication and Signaling

Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation

(2016) Xiao Li et al.   EBioMedicine

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

(2016) Li Hu et al.   Scientific Reports

Pathologic function and therapeutic potential of exosomes in cardiovascular disease

(2015) Shaina Ailawadi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

(2015) Henry Heberle et al.   BMC BIOINFORMATICS

Systematic review of factors influencing extracellular vesicle yield from cell cultures

(2015) Johann Mar Gudbergsson et al.   CYTOTECHNOLOGY

Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair

(2015) Giovanna Leoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Keratinocyte Microvesicles Regulate the Expression of Multiple Genes in Dermal Fibroblasts

(2015) Ping Huang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

(2015) Dongdong Ti et al.   Journal of Translational Medicine

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

(2015) Jieyuan Zhang et al.   Journal of Translational Medicine

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

(2015) Joel Z. Nordin et al.   Nanomedicine-Nanotechnology Biology and Medicine

HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing

(2015) Bin Zhang et al.   STEM CELLS

Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro

(2015) Arsalan Shabbir et al.   STEM CELLS AND DEVELOPMENT

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

The murine excisional wound model: Contraction revisited

(2015) Lin Chen et al.   WOUND REPAIR AND REGENERATION

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

(2015) Charles P. Lai et al.   Nature Communications

Human Umbilical Cord Mesenchymal Stem Cell Exosomes Enhance Angiogenesis Through the Wnt4/β-Catenin Pathway

(2015) Bin Zhang et al.   Stem Cells Translational Medicine

SYRCLE’s risk of bias tool for animal studies

(2014) Carlijn R Hooijmans et al.   BMC Medical Research Methodology

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging

(2014) CRISTINA GRANGE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Paracrine effects of stem cells in wound healing and cancer progression

(2014) JÜRGEN DITTMER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type

(2014) M. Sasaki et al.   JOURNAL OF IMMUNOLOGY

Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial Microparticles

(2013) Felix Jansen et al.   CIRCULATION

A multinational health professional perspective of the prevalence of mood disorders in patients with acute and chronic wounds

(2013) Dominic Upton et al.   International Wound Journal

The Complete Exosome Workflow Solution: From Isolation to Characterization of RNA Cargo

(2013) Jeoffrey Schageman et al.   Biomed Research International

Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration

(2012) T. Dinh et al.   DIABETES

Bone Marrow-Derived Mesenchymal Stem Cells Repaired but Did Not Prevent Gentamicin-Induced Acute Kidney Injury through Paracrine Effects in Rats

(2012) Luciana A. Reis et al.   PLoS One

Mesenchymal Stem Cell Therapy for Cutaneous Wounds

(2012) Anne M. Hocking   Advances in Wound Care

Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases

(2011) Bas W.M. van Balkom et al.   KIDNEY INTERNATIONAL

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Factors Affecting Wound Healing

(2010) S. Guo et al.   JOURNAL OF DENTAL RESEARCH

Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts

(2010) Abelardo Medina et al.   WOUND REPAIR AND REGENERATION